个人简介
1970年出生,博士。1992年获复旦大学学士学位,1995年获复旦大学硕士学位,2001年获耶鲁大学博士学位。2001-2004年在耶鲁大学先作为博士后、后作为副研究员进行功能基因组及发育生物学研究。 2004至今,复旦大学生命科学学院发育生物学研究所副教授、教授。曾获新世纪优秀人才(New Century Talents),浦江人才 (Pujiang Talents) 。
研究领域
主要运用发育生物学并结合其他生物学二级学科等理论和方法以研究小鼠基因组功能及发育分子机理。目前专注于:1)和侯宪玉教授一起在生物体质量控制机制(干细胞与发育、衰老及疾病)以及肠道菌群与发育方面展开全方位合作研究,2)小鼠横纹肌发育相关疾病机制研究
近期论文
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Danni Yu, Quanhui Dai, Zixiang Wang, Steven X Hou, Ling V Sun, ARF1 maintains intestinal homeostasis by modulating gut microbiota and stem cell function, Life Sci. 2023 Sep 1:328:121902. doi: 10.1016/j.lfs.2023.121902. Epub 2023 Jun 29.
Poonam Aggarwal , Zilun Liu, Guang Qian Cheng, Shree Ram Singh, Chunmei Shi, Ying Chen, Ling V Sun, Steven X Hou, Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila, Cell Rep 2022 Jun 21;39(12):110958
Lin F-H, Wang A, Dai W, Chen S, Ding Y, Sun LV. Lmod3 promotes myoblast differentiation and proliferation via the AKT and ERK pathways. Exp Cell Res. 2020;396(2):112297.
Dong Yang, Ruiqi Liao, Yun Zheng, Ling Sun, Tian Xu.Analysisof PBase Binding Profile Indicates an Insertion Target SelectionMechanism Dependent on TTAA, But Not Transcriptional Activity. Int J Biol Sci. 2016; 12(9): 1074–1082. Published online 2016 Jul 18. doi: 10.7150/ijbs.15589, PMCID: PMC4997051
Shuang Li, Kaiqi Mo, Hong Tian, Chen Chu, Shuna Sun, Lei Tian, Sheng Ding, Tong-ruei Li, Xiaohui Wu, Fang Liu, Zhen Zhang, Tian Xu, Ling V. Sun. Lmod2piggyBac mutant mice exhibit dilatedcardiomyopathy. Cell Biosci. 2016; 6: 38. Published online 2016 Jun 4. doi: 10.1186/s13578-016-0101-y
Tian L, Ding S, You Y, Li T, Liu Y, Wu X, Sun L, Xu T. Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy. Dis Model Mech. 2015 June 1; 8(6): 635–641. doi: 10.1242/dmm.019430