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个人简介

2017-至今 兰州大学,功能有机分子化学国家重点实验室,教授。 2014-2016 河海大学,力材学院教授,博导。 2013-2016 南京基诺美生物科技有限公司,总经理 2010-2013 南京金斯瑞生物科技有限公司,副总裁,兼新技术开发部总监。 2007-2009 美国GenScript 公司,研发部总监。 2006-2007 美国GenScript 公司,蛋白部总监 2004-2006 美国GenScript 公司,主任研究员 1999-2004 美国PharmaSeq, Inc.,高级科学家 1998-1999 哥伦比亚大学(导师: David J. Volsky),博士后 1993-1998 罗格斯大学(导师: Tariq M. Rana),理学博士 1987-1990 兰州大学化学系,理学硕士 1982-1987 兰州大学化学系,理学学士

研究领域

高通量药物筛选,合成生物学,蛋白质和多肽,多肽药物

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.“Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: Potential role in neuropathogenesis". Zhuying Wang, Gusta Trillo Pazos, Seon Young Kim, Mario Canki, Susan Morgello, Leroy R. Sharer, Harris A. Gelbard, Zaozhong Su, Dongchul Kang, Andrew I. Brooks, Paul B. Fisher, and David J. Volsky*, J. of NeuroVirology, 2004, 10 (Suppl.1),1-8. 2.“Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp 120". Zhuying Wang, Olga Pekarskaya, Meryem Bencheikh, Wei Chao, Harris A. Gelbard, Anuja Ghorpade, Jeffrey D. Rothstein, and David J. Volsky*, Virology, 2003, 312(1), 60-73. 3.“Probing Tat Peptide-TAR Interactions by Psoralen Photo-Cross-Linking". Zhuying Wang, Kavita Shah and Tariq M. Rana*, Biochemistry, 2001, 40, 6458-6464. 4.“Probing RNA-Protein Interaction by Psoralen photocrosslinking". Zhuying Wang and Tariq M. Rana*, Methods Mol. Biol., 1999, 118, 49-62. 5.“Proximity of a Tat peptide to the HIV-1 TAR RNA loop region determined by Site-Specific Photo-Cross-linking". Zhuying Wang and Tariq M. Rana*, Bioconjugate Chemistry, 1999, 10, 512-519. 6.“RNA-Protein Interactions in the Tat-TAR Complex Determined by Site-Specific Photocrosslinking". Zhuying Wang and Tariq M. Rana*, Biochemistry, 1998, 37, 4235-4243. 7.“DNA Damage-Dependent Transcriptional Arrest and Termination of RNA Polymerase II Elongation Complexes in DNA Template Containing HIV-1 Promoter". Zhuying Wang and Tariq M. Rana*, Proc. Natl. Acad. Sci. USA, 1997, 9, 6688-6693. 8.“RNA Conformation in Tat-TAR Complex Determined by Site-Specific Photocrosslinking". Zhuying Wang and Tariq M. Rana*, Biochemistry, 1996, 35, 6491-6499. 9.“Protein Orientation in Tat-TAR Complex Determined by Psoralen Photocrosslinking". Zhuying Wang and Tariq M. Rana*, J. Biol. Chem., 1996, 271, 16995-16998. 10.“Chemical Conversion of a TAR RNA-Binding Fragment of HIV-1 Tat Protein into a Site-Specific Crosslinking Agent". Zhuying Wang, Kavita Shah and Tariq M. Rana*, J. Amer. Chem. Soc., 1995, 117, 5438-5444.

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