个人简介
2015-至今 兰州大学药学院,教授
2012-2015 东京大学药学院,博士(指导教师:金井求)
2009-2012 中国科学研究院上海有机化学研究所,硕士(指导教师:李昂)
2007-2008 助理研究员,百灵威技术有限公司
2006-2007 助理研究员,江苏豪森药业有限公司
2002-2006 兰州大学化学化学化工学院,学士
研究领域
以具有抗癌活性的天然产物为基础,以发散性和汇聚式的合成为策略,以开发新的化学反应为手段,以简洁高效为宗旨,以商业化为引擎,合成具有商业前景的复杂分子及其类似物,探寻新的抗癌药物
近期论文
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1.“Total Syntheses of Anominine and Tubingensin A”. M. Bian#,Z. Wang# (#共同一作), X. C. Xiong, Y. Sun; C. Matera,K. C. Nicolaou*, A. Li*, J. Am. Chem. Soc., 2012, 134, 8078.
2.“Palladium-Catalyzed C(sp2)-C(sp3) Coupling Reaction between Arenes and Oxiranes via C-H Bond Activation”. Z. Wang, Y. Kuninobu*, M. Kanai*, J. Am. Chem. Soc., 2015, 137, 6140.
3.“Copper-Catalyzed Intramolecular C(sp3)-H and C(sp2)-H Amidation by Oxidative Cyclization”. Z. Wang, J. Ni, Y. Kuninobu*, M. Kanai*, Angew. Chem. Int. Ed., 2014, 53, 3496.
4.“Pd-catalyzed oxidative cross-coupling between two electron rich heteroarenes”. C. Y. He, Zh. Wang, C. Z. Wu, F. L. Qing*, X. G. Zhang*, Chem. Sci., 2013, 4, 3508.
5.“Copper-Mediated Direct C(sp3)-H and C(sp2)-H Acetoxylation”. Z. Wang, Y. Kuninobu*, M. Kanai*, Org. Lett., 2014, 16, 4790.
6.“Direct Access to α-Sulfenylated Amides/Esters via Sequential Oxidative Sulfenylation and C-C Bond Cleavage of 3-Oxobutyric Amides/Esters”. Y. Jiang, J.-D. Deng, H.-H. Wang, J.-X. Zou, Y.-Q. Wang, J.-H. Chen, L.-Q. Zhu, H.-H. Zhang, X. Peng,* Z. Wang*. Chem. Commun., 2017. DOI: 10.1039/C7CC09026A.
7.“Sodium Iodide (NaI)-Catalyzed Cross-Coupling for C−S Bond Formation via Oxidative Dehydrogenation: Cheap, Direct Access to Unsymmetrical Aryl Sulfides”. Wang H.-H.; Shi T.; Gao W.-W.; Wang Y.-Q.; Li J.-F.; Jiang Y.; Hou Y.-S.; Chen C.; Peng X.* Wang Z.* Chem. Asian. J., 2017, 12, 2675.
8.“Copper-Catalyzed Intramolecular N-S Bond Formation by Oxidative Dehydrogenative Cyclization”. Zh. Wang, Y. Kuninobu*, M. Kanai*, J. Org. Chem. 2013, 78, 7337.
9.“Double 1, 4-addition of (thio)salicylamides/thiosalicylic acids with propiolate derivatives: a direct, general synthesis of diverse heterocyclic scaffolds”. Wang, H.-H.; Shi; T.; Gao, W.-W.; Zhang, H.-H.; Wang, Y.-Q.; Li, J.-F.; Jiang, Y.; Hou, Y.-S.; Chen, J.-H.; Peng, X.;* Wang, Z.*, Org. Biomol. Chem., 2017, 15, 8013.