个人简介
1998–2002 内蒙古农业大学生物工程学院生物技术专业理学学士
2002–2005 内蒙古农业大学动物科学与医学学院动物营养专业农学硕士
2005–2008 中国农业科学院饲料研究所农业微生物专业农学博士
2008年中国农业科学院生物技术研究所参加工作
2009年晋升助理研究员
2013年至今任中国农业科学院生物技术研究所副研究员
研究领域
研究方向微生物酶基因工程和蛋白质工程。包括基因挖掘、基因表达调控、高效生物反应器(毕赤酵母,大肠杆菌,乳酸菌等)的构建、发酵工艺研究、蛋白分离纯化、蛋白性质研究和蛋白质分子改造等。
近期论文
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1.Yuhong Zhang, Pengjun Shi, Wanli Liu, Kun Meng, Yingguo Bai, Guozeng Wang, Zhichun Zhan, Bin Yao. Lipase diversity in glacier soil based on analysis of metagenomic DNA fragments and cell culture. Journal of microbiology and Biotechnology[J], 2009,19(9): 888-897.
2.Zhaowei Gao,Zhuofu Li,Yuhong Zhang,Huoqing Huang,Mu Li,Liwei Zhou,Yunming Tang,Bin Yao,Wei Zhang. High-level expression of the Penicillium notatum glucose oxidase gene in Pichia pastoris using codon optimization. Biotechnol Lett[J]. 2012,34: 507–514.
3.Zhang Yuhong, Xu Xiaolu, Zhou Xiaojin, Chen Rumei, Yang Peilong, Meng Qingchang, Meng Kun, Luo Huiying, Yuan Jianhua, Yao Bin, Zhang Wei. Overexpression of an acidic endo-β-1,3-1,4-glucanase in transgenic maize seed for direct utilization in animal feed[J]. PLoS ONE, 2013, 8(12):e81993.
4.Tian Jian, Zhang Yuhong, Liu Bo, Zuo Dongyang, Jiang Tao, Guo Jun, Zhang Wei, Wu Ningfeng, Fan Yunliu. Presep: predicting the propensity of a protein being secreted into the supernatant when expressed in Pichia pastoris[J]. PLoS One, 2013, 8(11):e79749.
5.Nie Chunming, Liu Bo, Zhang Yuhong, Zhao Guofen, Fan Xiaohu, Ning Xiaoyan, Zhang Wei. Production and secretion of Lactobacillus crispatus β-galactosidase in Pichia pastoris[J]. Protein Expres Purif, 2013, 92(1):88-93.
6.Xu Xiaolu, Zhang Yuhong, Meng Qingchang, Meng Kun, Zhang Wei, Zhou Xiaojin, Luo Huiying, Chen Rumei, Yang Peilong, Yao Bin. Overexpression of a Fungal β-Mannanase from Bispora sp. MEY-1 in Maize Seeds and Enzyme Characterization[J]. PLoS ONE, 2013, 8(2):e56146.
7.Liu Bo, Zhang Yuhong, Zhang Wei. RNA-Seq-Based Analysis of Cold Shock Response in Thermoanaerobacter tengcongensis, a Bacterium Harboring a Single Cold Shock Protein Encoding Gene[J]. PLoS ONE, 2014, 9(3):e93289.
8.Yang Wenxia, Zhang Yuhong, Zhou Xiaojin, Zhang Wei, Xu Xiaolu, Chen Rumei, Meng Qingchang, Yuan Jianhua, Yang Peilong, Yao Bin. Production of a Highly Protease-Resistant Fungal α-Galactosidase in Transgenic Maize Seeds for Simplified Feed Processing[J]. PLoS ONE, 2015, 10(6):e0129294.
9.Xu Xinxin, Li Jinyang, Zhang Wei, Huang Huoqing, Shi Pengjun, Luo Huiying, Liu Bo, Zhang Yuhong, Zhang Zhifang, Fan Yunliu, Yao Bin. A Neutral Thermostable β-1,4-Glucanase from Humicola insolens Y1 with Potential for Applications in Various Industries[J]. PLoS ONE, 2015, 10(4):e0124925.
10.Xu Shuxia, Qin Xing, Liu Bo, Zhang Deqing, Zhang Wei, Wu Kun, Zhang Yuhong. An acidic pectin lyase from Aspergillus niger with favorable efficiency in fruit juice clarification[J]. Lett Appl Microbiol, 2015, 60(2):181-187.