羊晓东 - 云南大学

个人简介

教育经历 2005.09-2009.12，云南大学，有机化学（有机及药物合成方向），理学博士 2000.09-2003.07，云南大学，有机化学（天然药物化学方向），理学硕士 1991.09-2003.07，云南民族大学，化学，理学学士工作经历 2023.04-至今，云南大学，药学院，教育部自然资源药物化学重点实验室，教授 2016.08-2023.04，云南大学, 教育部自然资源药物化学重点实验室，教授 2015.08-2016.08，宾夕法尼亚大学，化学系，访问学者 2010.11-2015.08，云南大学，化学科学与工程学院·药学院，教授 2006.01-2010.10，云南大学，化学科学与工程学院·药学院，副教授 2003.07-2005.12，云南大学，药学院，讲师 1995.07-2003.04，云南农业大学，基础科学部，助教/讲师

研究领域

1）药物化学：药物分子的设计、合成及构效关系研究；生物活性天然产物的合成及转化。 2）有机合成化学：基于偶联反应的有机合成方法学；催化合成反应；自由基化学

近期论文

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Yonggang Jiang, Dongxiang Liu, Madeline E. Rotella, Guogang Deng, Zhengfen Liu, Wen Chen, Hongbin Zhang*, Marisa C. Kozlowski*, Patrick J. Walsh*, Xiaodong Yang*, Net-1,2-hydrogen atom transfer of amidyl radicals: Toward the synthesis of 1,2-diamine derivatives, Journal of the American Chemical Society, 2023, 145(29), 16045-16057. (IF = 15.0，中科院I区top) Shengzu Duang, Ya Du, Lingling Wang, Xun Tian, Yujin Zi, Hongbin Zhang*, Patrick J. Walsh*, Xiaodong Yang*, Catalytic chemo- and regioselective radical carbocyanation of 2-azadienes for the synthesis of α-amino nitriles, Angewandte Chemie International Edition, 2023, 62(19), e202300605. (IF = 16.823，中科院I区top) Guogang Deng, Minyan Li, Kaili Yu, Chunxiang Liu, Zhengfen Liu, Shengzu Duan, Wen Chen, Xiaodong Yang*, Hongbin Zhang*, Patrick J Walsh*, Synthesis of benzofuran derivatives through cascade radical cyclization/intermolecular coupling of 2-azaallyls, Angewandte Chemie International Edition, 2019, 58(9), 2826-2830. (IF = 16.823，中科院I区top) Guogang Deng, Shengzu Duan, Jing Wang, Zhuo Chen, Tongqi Liu, Wen Chen, Hongbin Zhang*, Xiaodong Yang*, Patrick J. Walsh*, Transition-metal-free allylation of 2-azaallyls with allyl ethers through polar and radical mechanisms, Nature Communications, 2021, 12, 3860. (IF = 17.694，中科院I区top) Wen Chen, Yonghui Ma, Wenyan He, Yinxia Wu, Yuancheng Huang, Yipeng Zhang, Hongchang Tian, Kai Wei, Xiaodong Yang*, Hongbin Zhang*, Structure units oriented approach towards collective synthesis of sarpagine-ajmaline-koumine type alkaloids, Nature Communications, 2022, 13, 908. (IF = 17.694，中科院I区top) Lun Li, Jiangtao Ren, Jingjie Zhou, Xiaomei Wu, Zhihui Shao*, Xiaodong Yang*, Deyun Qian*, Enantioselective synthesis of N-alkylindoles enabled by nickel-catalyzed C-C coupling, Nature Communications, 2022, 13, 6861. (IF = 17.694，中科院I区top) Shengzu Duan, Yujin Zi, Lingling Wang, Jielun Cong, Wen Chen, Minyan Li*, Hongbin Zhang*, Xiaodong Yang*, Patrick J. Walsh*, α-Branched amines through radical coupling with 2-azaallyl anions, redox active esters and alkenes, Chemical Science, 2022, 13(18), 3740-3747. (IF = 9.969，中科院I区top) Shengzu Duan, Guogang Deng, Yujin Zi, Xiaomei Wu, Xun Tian, Zhengfen Liu, Minyan Li*, Hongbin Zhang*, Xiaodong Yang*, Patrick J. Walsh*, Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions, Chemical Science, 2021, 12(18), 6406-6412. (IF = 9.969，中科院I区top) Zhengfen Liu, Minyan Li, Guogang Deng, Wanshi Wei, Ping Feng, Quanxing Zi, Tiantian Li, Hongbin Zhang*, Xiaodong Yang*, Patrick J. Walsh*, Transition-metal-free C(sp3)–H/C(sp3)–H dehydrogenative coupling of saturated heterocycles with N-benzyl imines, Chemical Science, 2020, 11(29), 7619-7625. (IF = 9.969，中科院I区top) Linlin Zhang, Zhengfen Liu, Xun Tian, Yujin Zi, Shengzu Duan, Yongsheng Fang, Wen Chen, Hong Jing, Lijuan Yang*, Xiaodong Yang*, Transition-metal-free C(sp3)−H coupling of cycloalkanes enabled by single-electron transfer and hydrogen atom transfer, Organic Letters, 2021, 23(5), 1714-1719. (IF = 6.072，中科院I区top) Shengzu Duan, Yujin Zi, Ya Du, Jielun Cong, Xiaotong Sun, Hong Jing, Jingfeng Zhao*, Wen Chen*, Xiaodong Yang*, Radical C(sp3)S Coupling for the Synthesis of α-Amino Sulfides, Organic Letters, 2023, 25, DOI: 10.1021/acs.orglett.3c01121. (IF = 6.072，中科院I区top)