当前位置: X-MOL首页全球导师 国内导师 › 辛伟贤

个人简介

学历简介: 博士 2000-1 至 2004-6 香港大学 (The University of Hong Kong) 应用化学(荣誉)理学士 1996-9 至 1999-7 香港城市大学 (City University of Hong Kong) 工作经历: 2013年10月 至 2016年9月 香港大学 名誉助理教授 2009年2月 至 2013年7月 香港大学 助理教授(研究) 2006年2月 至 2009年1月 香港大学 博士后 2012年10月 至 2013年2月 英国华威大学 访问学者 2008年6月 至 2008年9月 中国科学院上海药物安全评价研究中心 访问学者

研究领域

生物无机化学研究,包括将多种在生理条件下稳定的过渡金属配合物应用于抗癌,抗癌干细胞及抗病毒药物的研究。近年也与Novus Life Sciences Limited(美國財經頻道CNBC 2014年全球20間最炙手可熱的初創企業之一)共同开发新的生物材料和应用

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

[ 1 ] Sun, R. W.-Y.(辛伟贤)*;Recent Development (from 2013 to 2015) of Gold-Based Compounds as Potential Anti-Cancer Drug Candidates;Cancer Therapy: Recent Progress and Future Perspectives, Bentham Science Publishers; [ 2 ] Sun, R. W.-Y.*(辛伟贤); Zhang, M.; Li, D.*; Zhang, Z.-F.; Cai, H.; Li, M.; Xian, Y.-J.; Ng, S. W.; Wong, A. S.-T. (*corresponding authors);Dinuclear gold(I) pyrrolidinedithiocarbamato complex: cytotoxic and antimigratory activities on cancer cells and the use of metal-organic framework;Chemistry A European Journal (impact factor: 5.731), 2015, in press.; [ 3 ] Andermark, V.; G?ke, K.; Kokoschka, M.; Abu el Maaty, M. A.; Lum, C. T.; Zou, T.; Sun, R. W.-Y.(辛伟贤); Aguiló, E.; Oehninger, L.; Rodríguez, L.; Bunjes, H.; Wolfl, S.; Che, C.-M.; Ott, Ingo.;Alkynyl gold(I) phosphane complexes: evaluation of structure-activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex;Journal of Inorganic Biochemistry (impact factor: 3.444), submitted.; [ 4 ] Hou, Y.-L.; Li, S.-X.; Sun, R. W.-Y.(辛伟贤); Liu, X.-Y.; Ng, S. W.; Li, D.;Facile preparation and dual catalytic activity of copper(I)–metallosalen coordination polymers;Dalton Transactions (impact factor: 4.197), 2015, 44, 17360.; [ 5 ] Lai, K. K. Y.; Chan, K. T.; Choi, M. Y.: Wang, H. K.; Fung, E. Y.; Lam, H. Y.; Tan, W.; Tung, L. N.; Tong, D. K. H.; Sun, R. W.-Y.(辛伟贤); Lee, N. P.; Law, S.;14-3-3σ confers cisplatin resistance in esophageal squamous cell carcinoma cells via regulating DNA repair molecules;Tumor Biology (impact factor: 3.611), 2015, in press.; [ 6 ] Ni, W.-X.; Qiu, Y.-M.; Li, M.; Sun, R. W.-Y.(辛伟贤); Zhan, S.-Z.; Ng, S. W.; Li, D.;Metallophilicity-driven dynamic aggregation of a phosphorescent gold(I)?silver(I) cluster prepared by solution-based and mechanochemical approaches;Journal of the American Chemical Society (impact factor: 12.113), 2014, 136, 9532–9535; [ 7 ] Lum, C. T.; Sun, R. W.-Y.(辛伟贤), Zou, T.; Che, C.-M.;Gold(III) complexes inhibit growth of cisplatin-resistant ovarian cancer in association with upregulation of DNA mismatch repair gene PMS2;Chemical Science (impact factor: 8.314), 2014, 5, 1579–1584.; [ 8 ] Hou, Y.; Sun, R. W.-Y.(辛伟贤), Li, D.;“A copper(I)/copper(II)-salen coordination polymer as a bimetallic catalyst for three-component strecker reactions and degradation of organic dyes”.;Chemical Communications (impact factor: 6.378), 2014, 50, 2295–2297.; [ 9 ] Lum, C. T.; Wong, A. S.-T.; Lin, M. C. M.; Che, C.-M.;* Sun, R. W.-Y.(辛伟贤)* (*corresponding authors);Gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells;Chemical Communications (impact factor: 6.378), 2013, 49, 4364–4366.; [ 10 ] Sun, R. W.-Y.(辛伟贤)* (*corresponding author);Strategies to Improve the Anti-Cancer Properties of Gold(III) Complexes;Modern Chemistry & Applications (impact factor: not yet announced), 2013, 1, 102. doi: 10.4172/mca.1000102; [ 11 ] Sun, R. W.-Y.(辛伟贤); Lok, C.-N.; Fong, T. T.-H.; Li, C. K.-L.; Yang, Z.-F.; Zou, T.; Siu, A. F.-M.; Che, C.-M.;A dinuclear cyclometalated gold(III)-phosphine complex targeting thioredoxin reductase inhibits hepatocellular carcinoma in vivo;Chemical Science (impact factor: 8.314), 2013, 4, 1979–1988.; [ 12 ] Kwong, W.-L.; Sun, R. W.-Y.(辛伟贤); Lok, C.-N.; Siu, F.-M.; Wong, S.-Y.; Low, K.-H.; Che, C.-M.;An ytterbium(III) porphyrin induces endoplasmic reticulum stress and apoptosis in cancer cells: cytotoxicity and transcriptomic studies;Chemical Science (impact factor: 8.314), 2013, 4, 747–754; [ 13 ] Zhang, J. J.; Ng, K.-M.; Lok, C.-N.; Sun, R. W.-Y.(辛伟贤); Che, C.-M.;Deubiquitinases as potential anti-cancer targets for gold(III) complexes;Chemical Communications (impact factor: 6.378), 2013, 49, 5153–5155; [ 14 ] To, W.-P.; Zou, T.; Sun, R. W.-Y.(辛伟贤); Che, C.-M.;Light-Induced Catalytic and Cytotoxic Properties of Phosphorescent Transition Metal Compounds with a d8 Electronic Configuration;Philosophical Transactions of the Royal Society A (impact factor: 2.891), 2013, 371, 1995 20120126 [doi: 10.1098/rsta.2012.0126]; [ 15 ] Zhang, J. J.; Lu, W.; Sun, R. W.-Y.(辛伟贤);* Che, C.-M.* (*corresponding authors);Organogold(III) Supramolecular Polymers for Anti-Cancer Treatments;Angewandte Chemie-International Edition (impact factor: 13.734), 2012, 51, 4882–4886; [ 16 ] Zhang, J. J.; Sun, R. W.-Y.(辛伟贤); Che, C.-M.;A dual cytotoxic and anti-angiogenic water-soluble gold(III) complex induces endoplasmic reticulum damage in HeLa cells;Chemical Communications (impact factor: 6.378), 2012, 48, 3388–3390; [ 17 ] Lee, P.; Zhang, R.; Li, V.; Liu, X; Sun, R. W.-Y.(辛伟贤); Che, C.-M.; Wong, K. K. Y.;Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation;International Journal of Nanomedicine (impact factor: 3.463), 2012, 7, 731–737; [ 18 ] Liu, J.; Sun, R. W.-Y.(辛伟贤); Leung, C.-H.; Lok, C.-N.; Che, C.-M.;Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes;Chemical Communications (impact factor: 6.378), 2012, 48, 230–232; [ 19 ] Chan, S. L.-F.; Shek, L.; Huang, J.-S.; Chui, S. S.-Y.; Sun, R. W.-Y.(辛伟贤); Che, C.-M;Molecular wheels of ruthenium and osmium with bridging chalcogenolate ligands: edge-shared octahedra structures and metal ion bindings;Angewandte Chemie-International Edition (impact factor: 13.734), 2012, 51, 2614–2617; [ 20 ] Zhou, X.-P.; Liu, J.; Zhan, S.-Z.; Yang, J.-R.; Li, D.; Ng, K.-M.; Sun, R. W.-Y.(辛伟贤); Che, C.-M.;A High-symmetry Coordination Cage from 38 or 62 Components Self-Assembly;Journal of the American Chemical Society (impact factor: 10.677), 2012, 134, 8042–8045;

学术兼职

理学院国际合作交流办公室主任,理学院本科学生出国(境)学习奖学金评审小组组长,法国图卢兹大学客席教授,香港大学化学系名誉助理教授,香港大学合成化學國家重點實驗室主要成员

推荐链接
down
wechat
bug