田志远 - 中国科学院大学 - 化学与化工学院

个人简介

教育背景 2000-09--2005-07 中国科学院化学研究所研究生（硕博连读） 1991-09--1995-07 武汉大学大学本科工作简历 2011-03~现在, 中国科学院大学, 教授、博士生导师 2005-10~2011-02,皇后大学（加拿大），华盛顿州立大学（美国）等, 博士后 2005-03~2005-04,雷根斯堡大学（德国）, 访问学生 1995-09~2000-07,原电子工业部国营第752厂（武汉）, 助理工程师

研究领域

我们课题组的研究兴趣集中在具有光学活性的功能材料及其应用研究。具体而言，我们专注于对光具有应激-响应特性的功能材料的设计与合成，以及它们在生物成像（高分辨荧光成像及多模态联用成像）、生物光学探测（肿瘤标志物的光学探测）、治疗（光激活多重机制协同抗肿瘤）等方面的潜在应用研究。我们也关注材料的光学和光子学基本光物理特性，以及这些特性在光功能材料设计方面的应用。研究组正在开展的研究包括：（1）动态对比超分辨荧光成像及其在生物影像中的应用；（2）荧光标签和传感器；（3）光学活性材料及其在肿瘤诊疗中的应用。

近期论文

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MOFs-based nanoagent enables dual mitochondrial damage in synergistic antitumor therapy via oxidative stress and calcium overload, Nature Communications, 2021, 12: 6399. Corresponding author Near-infrared light-triggered platelet arsenal for combined photothermal-immunothreapy against cancer, Science Advances, 2021, 7: eabd7614. Corresponding author Correlative dual-alternating-color photoswitching fluorescence imaging and AFM enable ultrastructural analyses of complex structures with nanoscale resolution, Nanoscale, 2020, 12, 17203. Corresponding author A long-wavelength turn-on fluorescent probe for intracellular nanomolar level peroxynitrite sensing with second-level response, Talanta, 2020, 219, 121354. Corresponding author Single-chromophore-based therapeutic agent enables green-light-triggered chemotherapy and simultaneous photodynamic therapy to cancer cells, ACS Appl. Bio Mater., 2019, 2, 3068. Corresponding author A single-chromophore-based agent enables rapid sensing of intracellular hypochlorous acid and in-situ photodynamic therapy to cancer cells, Anal. Chem. Acta, 2019, 1061, 142. Corresponding author A super-sensitive ratiometric fluorescent probe for monitoring intracellular subtle pH fluctuation, Sens. Actuators B: Chem. 2018, 273, 167. Corresponding author A turn-on fluorescent probe for detection of sub-ppm levels of a sulfur mustard simulant with high selectivity, Anal. Chem., 2018, 90, 5481. Corresponding author Cancer cell membrane-biomimetic nanoprobes with two-photon excitation and near-infrared emission for intravital tumor fluorescence imaging, ACS Nano, 2018, 12, 1350. Corresponding author A new colorimetric, near-infrared fluorescent probe for rapid detection of palladium with high sensitivity and selectivity, Talanta, 2018,183, 164. Corresponding author Beyond a carrier: graphene quantum dots as a probe for programmatically monitoring anti-cancer drug delivery, release, and response, ACS Appl. Mater. Interfaces, 2017, 9, 27396. Corresponding author A BODIPY-based fluorescent probe for detection of subnanomolar phosgene with rapid response and high selectivity, ACS Appl. Mater. Interfaces, 2017, 9, 13920. Corresponding author A flavone-basedturn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity, Talanta, 2016,146, 41. Corresponding author Photoswitching near-infrared fluorescence from polymer nanoparticles catapults signals over the region of noises and interferences for enhanced sensitivity, ACS Appl. Mater. Interfaces, 2016, 8, 4399. Corresponding author Photoswitchable fluorescent nanoparticles and their emerging applications, Nanoscale, 2015, 7, 19342. Corresponding author Conjugated polymer-based hybrid nanoparticles with two-photon excitation and near-infrared emission features for fluorescence bioimaging within the biological window, ACS Appl. Mater. Interfaces, 2015, 7, 20640. Corresponding author Erythrocyte membrane-coated NIR-triggered biomimetic nanovectors with programmed delivery for photodynamic therapy of cancer, Nanoscale, 2015, 7, 9806. Corresponding author Antiphase dual-color correlation in a reactant−product pair imparts ultrasensitivity in reaction-linked double-photoswitching fluorescence imaging, J. Am. Chem. Soc., 2015, 137, 4312. Corresponding author Single-fluorophore-based fluorescent probes enable dual-channel detection of Ag+ and Hg2+ with high selectivity and sensitivity, Anal. Chem. Acta, 2014, 839, 74. Corresponding author Al3+-induced far-red fluorescence enhancement of conjugated polymer nanoparticles and its application in live cell imaging, Nanoscale, 2013, 5, 9340, Corresponding author