Falke, Joseph - University of Colorado - Chemistry and Biochemistry

个人简介

Ph.D.: California Institute of Technology, 1985 Postdoctoral Fellow: NIH Postdoctoral Fellow at University of California, Berkeley, 1985-87

研究领域

Cell Signaling Membranes Molecular Biophysics Proteins & Enzymology Structural Biology Biophysics

近期论文

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Bass, R.B. and J.J. Falke (1999) The aspartate receptor cytoplasmic domain: In situ chemical analysis of structure, mechanism and dynamics. Structure 7, 829-40. Bass, R.B., Coleman M.D. and J.J. Falke (1999) Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: Cysteine and disulfide scanning studies. Biochemistry 38, 9317-27. Trammell, M.A. and J.J. Falke (1999) Identification of a site critical for kinase regulation on the central processing unit (CPU) helix of the aspartate receptor. Biochemistry 38, 329-36. Nalefski, E.A. and J.J. Falke (1998) Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2. Biochemistry 37, 17642-50 (Accelerated Publication). Hazard, A.L., S.C. Kohout, N.L. Stricker, J.A. Putkey, and J.J. Falke (1998) The kinetic cycle of cardiac troponin C: Calcium binding and dissociation at site II trigger slow conformational rearrangements. Protein Science 7, 2451-9. Bass, R.B. and J.J. Falke (1998) Detection of a conserved a-helix in the kinase docking region of the aspartate receptor by cysteine and disulfide scanning. J. Biol. Chem. 273, 25006-25014. Butler, S.B. and J.J. Falke (1998) Cysteine and disulfide scanning reveals two amphiphillic helices in the linker region of the aspartate chemoreceptor. Biochemistry 37, 10746-10756. Nalefski, N.A., T. McDonagh, W. Somers, J. Seehra, J.J. Falke, and J.D. Clark (1998) Independent folding and ligand specificity of the C2 domain of cPLA2. J. Biol. Chem. 273, 1365-1372.