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个人简介

1989.4---至今,山东大学药学院新药药理教研室,从事药理学实验教学及科研工作; 2000.10 晋升为高级实验师。

近期论文

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1.Subo Wang,Yanna Cheng, Fengshan Wang, Lirui Sun, Chunhui Liu, Guanjun Chen, Yuhua Li, S.G. Ward, Xianjun Qu*. Inhibition activity of sulfated polysaccharide of Sepiella maindroni ink on matrix metalloproteinase (MMP)-2. Biomedicine & Pharmacotherapy; 2008, 62(5): 297-302. 2.Ming-hui Chen, Shu-xiang Cui,Yan-na Cheng, Li-rui Sun, Qian-bin Li, Wen-fang Xu, S.G Ward, Wei Tang, Xian-jun Qu*. Galloyl cyclic-imide derivative CH1104I inhibits tumor invasion via suppressing matrix metalloproteinase activity. Anti-cancer drugs, 2008; 19(10):957-965. 3.Su-Bo Wang,Yan-Na Cheng, Shu-Xiang Cui, Julia Li Zhong, S. G. Ward, Li-Rui Sun, Ming-Hui Chen, Norihiro Kokudo, Wei Tang, Xian-Jun Qu*. Des-c-carboxy prothrombin stimulates human vascular endothelial cell growth and migration. Clin Exp Metastasis ; 2009, 26:469–477. 4.Li-rui Sun, Xun Li,Yan-na Cheng, Hong-yu Yuan, Ming-hui Chen, Wei Tang, Stephen Geoffrey Ward, Xian-jun Qu* Reversal effect of substituted 1,3-dimethyl-1H- quinoxalin-2-ones on multidrug resistance in adriamycin-resistant K562/A02 cells. Biomedicine & Pharmacotherapy ; 2009, 63: 202-208. 5.Ou Y, Dong X, Liu XY, Cheng XC,Cheng YN, Yu LG, Guo XL Mechanism of Tetramethylpyrazine analogue CXC195 inhibition of hydrogen peroxide- induced apoptosis in human endothelial cells. Biol Pharm Bull ; 2010 ; 33(3):432-8 6.Yang Ou, Xiu-Li Guo, Li Zhai, Xin-Yong Liu,Yan-na Cheng TMPDP, a tetramethylpyrazine derivative, protects vascular endothelial cells from oxidation damage by hydrogen peroxide. Pharmazie; 2010 Oct;65(10):755-9. 7.Gao JJ, Gao ZH, Zhao CR, Yuan Y, Cui SX, Zhang XF,Cheng YN, Xu WF, Tang W, Qu XJ. LYP, a novel bestatin derivative, inhibits cell growth and suppresses APN/CD13 activity in human ovarian carcinoma cells more potently than bestatin. Invest New Drugs ; 2011,29:574–582 SCI 8.Li-na Hao, Qing-zhu Zhang, Tian-gui Yu, Lihong Yu,Yan-na Cheng Modulation of Ultra Low Molecular Weight Heparin on [Ca2+]i in nervous cells. Brain Research Bulletin ; 2011, 86: 355-359. 9.Ting ZhaoYan-Na Cheng, Hai-Ning Tan, Jin-Feng Liu, Huan-Li Xu, Guang-Li Pang, and Feng-Shan Wang*. Site-Specific Chemical Modification of Human Serum Albumin with Polyethylene Glycol Prolongs Half-life and Improves Intravascular Retention in Mice. Biol Pharm Bull; 2012, 35(3): 280-288. 10.Xiuzhen Han, Si Gao,Yanna Cheng, Yanzhe Sun, Wei Liu, Linlin Tang, ongmei Ren. Protective effect of naringenin-7-O-glucoside against oxidative stress induced by doxorubicin in H9c2 cardiomyocytes . BioScience Trends. 2012; 6(1):19-25.

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