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个人简介

1996.09-2000.07于山东大学药学院药学专业,获学士学位;2000年推荐免试为山东大学药学院药物化学专业研究生,2003.07获医学硕士学位;同年留校任教至今。2005.09聘任为讲师。于2006.09-2009.10获国家留学基金委资助,在瑞士日内瓦大学植化与生药学专业攻读博士学位,并担任助教工作,于2009年7月获理学博士学位。2010年12月起获得硕士生指导教师资格;2011年12月起聘任为山东大学副教授。2013-2015年于山东大学医学院进行博士后学习。

研究领域

长期从事活性天然产物发现,中药药效物质研究工作,对具有传统用药价值的中药进行生物活性筛选、活性物质发现、作用机制探讨等研究,并尝试与其传统应用相关联。另一方面,也关注植物中所含化学成分的生态学意义,比如化感作用。近年来,也尝试活性天然产物的结构改造及其活性研究工作。除国内合作外,与瑞士日内瓦大学、澳大利亚南澳大学的药学同行建立了长期合作关系,可协助完成生物活性研究工作。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Zhang CM, Ji JB, Ji M, Fan PH*. Acetylcholinesterase inhibitors and compounds promoting SIRT1expression from Curcuma xanthorrhiza. Phytochemistry Letters , 2015,12: 215–219 . 2. PH Fan, MT Zang, J Xing.* Oligosaccharides composition in eight food legumes species as detected by high resolution mass spectrometry. Journal of the Science of Food and Agriculture, 2015, 95:2228-2236. 3. CM Zhang, PH Fan*, M Li, and HX Lou.* Two New sesquiterpenoids from the Rhizomes of Curcuma xanthorrhiza. Helvetica Chimica Acta, 2014, 97:1295-1300. 4. PH Fan, T Zhang, K Hostettmann, Anti-inflammatory activity of the invasive neophyte Polygonum cuspidatum Sieb. And Zucc. (Polygonaceae) and the chemical comparison of the invasive and native varieties with regard to resveratrol. Journal of traditional and complementary Medicine, 2013, 3(3): 182-187. 5. PH Fan, LX Zhao, K Hostettmann, HX Lou. Chemical constituents of Asplenium ruta-muraria L.Natural Product Research, 2012, 26(15):1413-1418. 6. HY Lou, PH Fan, RG Perez, HX Lou Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death Bioorganic & Medicinal Chemistry, 2011, 19 :4021–4027. 7. PH Fan, K Hostettmann, HX Lou. Allelochemicals of the invasive neophyte Polygonum cuspidatum Sieb. & Zucc. (Polygonaceae). Chemoecology, 2010, 20:223–227. 8. PH Fan, L Terrier, AE Hay, A Marston,K Hostettmann. Antioxidant and enzyme inhibition activities and chemical profiles of the invasive plant Polygonum sachalinensis F.Schmidt ex Maxim (Polygonaceae). Fitoterapia, 2010, 81(2):124-131. 9. PH Fan, A Marston, AE Hay, K Hostettmann. Rapid separation of three glucosylated resveratrol analogues from the invasive plant Polygonum cuspidatum by high-speed countercurrent chromatography. Journal of Separation Science, 2009, 32: 2979-2984. 10. PH Fan, AE Hay, A Marston, K Hostettmann. Allelopathic potential of phenolic constituents from Polygonum cuspidatum Sieb. & Zucc (Polygonaceae), Planta Medica, 2009, 75:877-1094.

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