个人简介
1990.7-1993.9 山东医科大学口腔医院药师
1996.7-2000.9 山东医科大学教师
2000.9-至今 山东大学教师
2003.4-2003.12 国家食品药品监督管理局药品审评中心外聘新药注册审评专家(借调工作)
1990.7本科毕业于山东医科大学,获学士学位
1996.7研究生毕业于山东医科大学,获生化与微生物药物硕士学位
2003.9毕业于沈阳药科大学,获药剂学专业博士学位
2007.2山东大学药学博士后出站
2007.3-2008.3美国俄亥俄州立大学药学院访问学者
研究领域
1.药物缓控释、靶向给药系统
2.透皮吸收及鼻粘膜给药系统
3.生物医学纳米材料及生物药物给药系统
4.促进高分子药物或难溶性药物体内吸收的研究
近期论文
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1. Du H, Liu M, Yu A, Ji J, Zhai G. Insight into the role of dual-ligand modification in low molecular weight heparin based nanocarrier for targeted delivery of doxorubicin. Int J Pharm. 2017,523(1):427-438.
2. Yang X, Cai X, Yu A, Xi Y, Zhai G. Redox-sensitive self-assembled nanoparticles based on alpha-tocopherol succinate-modified heparin for intracellular delivery of paclitaxel. J Colloid Interface Sci. 2017, 496: 311- 326.
3. Zhang H, Xu J, Xing L, Ji J, Yu A, Zhai G. Self-assembled micelles based on Chondroitin sulfate/poly (d,l-lactideco-glycolide) block copolymers for doxorubicin delivery. J Colloid Interface Sci. 2017, 492: 101-111.
4. Duan Y, Zhang B, Chu L, Tong HH, Liu W, Zhai G. Evaluation in vitro and in vivo of curcumin-loaded mPEG-PLA/TPGS mixed micelles for oral administration. Colloids Surf B Biointerfaces. 2016,141:345-354.
5. Du H, Liu M, Yang X, Zhai G. The role of glycyrrhetinic acid modification on preparation and evaluation of quercetin-loaded chitosan-based self-aggregates.J Colloid Interface Sci. 2015, 460: 87-96.
6. Zhao L, Yang C, Dou J, Xi Y, Lou H, Zhai G. Development of RGD-Functionalized PEG-PLA Micelles for Delivery of Curcumin. J Biomed Nanotechnol. 2015, 11(3):436-46.
7. Du H, Liu M, Yang X, Zhai G. The design of pH-sensitive chitosan- based formulations for gastrointestinal delivery. Drug Discov Today. 2015, 20(8):1004-11
8. Duan Y, Cai X, Du H, Zhai G. Novel in situ gel systems based on P123/TPGS mixed micelles and gellan gum for ophthalmic delivery of curcumin. Colloids Surf B Biointerfaces. 2015, 128:322-30.
9. Zhao L, Wang Y, Zhai Y, Wang Z, Liu J, Zhai G. Ropivacaine loaded microemulsion and microemulsion-based gel for transdermal delivery: preparation, optimization, and evaluation. Int J Pharm. 2014, 477(1-2): 47-56.
10. Pang X, Lu Z, Du H, Yang X, Zhai G. Hyaluronic acid-quercetin conjugate micelles: synthesis, characterization, in vitro and in vivo evaluation. Colloids Surf B Biointerfaces. 2014,123:778-86.