个人简介
个人简历
2004年7月毕业于安徽大学生命科学学院,获得生物学学士学位;2007年7月毕业于云南农业大学植物保护学院(与云南省农科院生物技术与种质资源研究所联合培养),获得植物保护学硕士学位;2010年6月毕业于浙江大学农业与生物技术学院,获得生化与分子生物学博士学位;2008年8月至2009年8月在美国Samuel Roberts Noble Foundation国家公派访学。2010年8月至2013年8月,杭州师范大学生命与环境科学学院,助理研究员;2013年9月至2016年9月在加拿大农业部London Research and Development Centre从事博士后研究,2016年10月至2017年2月加拿大农业部London Research and Development Centre研究科学家;2013年9月至2017年9月杭州师范大学生命与环境科学学院,副研究员;2017年10月至今东北农业大学农学院,教授。
教学情况
开设课程:讲授本科生课程《分子生物学》
科研项目
1. 马铃薯X病毒编码的TGB2蛋白耦合病毒复制和运动的分子机理研究,国家自然基金面上项目(2017.1-2020.12),60万,主持
2. 植物病毒抑制寄主系统性获得免疫的分子机理及应用研究,黑龙江省自然科学基金重点项目(2018/7-2021/7),20万,主持
3. 东北农业大学人才启动基金(“东农学者计划” 学术骨干项目)(2018.1-2020.12),50万,主持
4. 利用人工锌指蛋白进行多价抗双生病毒的研究,国家自然基金青年项目(2012/01 2014/12),23万,主持
5. 棉花GhACNAT基因调控花药发育的分子机理研究,国家自然科学基金面上项目(2017/1-2020/12),59万,参与
6. 基于人工锌指核酸酶抗双生病毒体系的建立与评价,浙江省自然科学基金一般项目(2011/01-2013/12),8万,主持
7. 苦苣菜黄网病毒P蛋白细胞核输出的生物学功能研究及寄主互作蛋白的分离鉴定,国家自然科学基金面上项目(2014/01-2014/12) 15万,参与
8. 一种新型耐热非特异性核酸酶的作用机制及功能进化研究,国家自然科学基金青年项目(2012/01-2014/12),23万,参与
9. 灰霉菌对APs类杀菌剂抗性分子机制的研究,国家自然科学基金青年项目(2012/01-2014/12),21万,参与
获得国家发明专利授权1项:
李正跃,张宏瑞,武晓云,程晓非,严乃胜,陈建斌,李作森,蓟马昆虫室内饲养罐(ZL200520100047)
论著
1. Cheng XF, Virk N, Wang HZ. Impact of the host on plant virus evolution. In: Gaur RK, Hohn T, Sharma P. eds. Plant Virus-Host Interaction: Molecular approaches and viral evolution. Academic Press (Oxford), 2014, pp. 359-371.
近期论文
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1.Cheng XF, Xiong RY, Li YZ, Li FF, Zhou XP, Wang AM*. Sumoylation of Turnip mosaic virus RNA polymerase promotes viral infection by counteracting the host NPR1-mediated immune response. The Plant Cell, 2017, 25:508-525. SCI 1区,IF=8.538
2.Cheng XF, Wang AM*. The potyvirus silencing suppressor protein VPg mediates degradation of SGS3 via ubiquitination and autophagy pathways. Journal of Virology, 2017, 91(1): e01478-16.SCI 2区,IF=4.606
3.Cheng XF, Deng P, Cui HG, Wang AM. Visualizing double-stranded RNA distribution and dynamics in living cells by dsRNA binding-dependent fluorescence complementation. Virology, 2015, 485: 439-451. SCI, IF=3.321(封面文章)
4.Wu XD, Wu XY, Li WB, Cheng XF*. Molecular characterization of a divergent strain of calla lily chlorotic spot virus infecting celtuce (Lactuca sativa var. augustana) in China. Archives of Virology, 2018, DOI: 10.1007/s00705-018-3743-8. SCI, IF=2.058
5.Wu XD, Cheng XF*, Li WB*. First report of natural infection of Watermleon mosaic virus on Lagerstroemia indica in China. Plant Disease, 2018, DOI: 10.1094/PDIS-10-17-1604-PDN.SCI 1区,IF=3.173
6.Cheng XF, Wang AM*. Multifaceted defense and counter-Defense in co-evolutionary arms race between plants and viruses. Communicative & Integrative Biology, 2017, 10:4, e1341025. SCI
7.Chen LY, Cheng XF, Cai JY, Zhan LL, Wu XX, Liu Q, Wu XY. Multiple virus resistance using artificial trans-acting siRNAs. Journal of Virological Methods, 2016, 228: 16-20. SCI,IF=1.781
8.Cheng XF, Li FF, Cai JY, Chen W, Zhao N, Sun YQ, Guo YS, Yang XL, Wu XY. Artificial TALE as a convenient protein platform for engineering broad-spectrum resistance to begomoviruses. Viruses, 2015, 7: 4772-4782. SCI 2区,IF=3.353
9.Wang YL+, Cheng XF+, Wu XX, Wang AM, Wu XY. Characterization of complete genome and small RNA profile of pagoda yellow mosaic associated virus, a novel badnavirus in China. Virus Research, 2014, 188: 103-108. SCI, IF= 2.324
10.Chen W, Qian YS, Wu XY, Sun YQ, Wu XX and Cheng XF*. Inhibiting replication of begomoviruses using artificial zinc finger nucleases that target viral-conserved nucleotide motif. Virus Genes, 2014, 48(3): 494-501. SCI, IF= 1.576
11.Cheng XF*, Virk N, Chen W, Ji SQ, Ji SY, Sun YQ and Wu XY*. CpG usage in RNA viruses: data and hypotheses. Plos One, 2013, 8(9): e74109. SCI 2区,IF= .3.534
12.Cheng XF, Chen W, Zhou ZH, Liu JJ, and Wang HZ. Functional characterization of a novel tropinone reductase-like gene in Dendrobium nobile Lindl. Journal of Plant Physiology, 2013, 170: 958-964.
13.Chen W+, Cheng XF+, Zhou Z, Liu J, and Wang H. Molecular cloning and characterization of a tropinone reductase from Dendrobium nobile Lindl. Molecular Biology Reports, 2013, 40: 1145-1154. (Co-first author). SCI, IF=2.024
14.Cheng XF*, Wu X, Wang H, et al. High codon adaptation in citrus tristeza virus to its citrus host. Virology Journal, 2012, 9: 113. (Corresponding author). SCI, IF= 2.181
15.Wu X, Ding H, Ke L, Xin Y, and Cheng XF* Characterization of an acid-resistant glucose 1-dehydrogenase from Bacillus cereus var. mycoides, Romanian Biotechnological Letters, 2012, 17(4): 7540-7548. (Corresponding author). SCI
16.Cheng XF, Wang X, Wu J, Briddon R, and Zhou X. βC1 encoded by tomato yellow leaf curl China betasatellite forms multimeric complexes in vitro and in vivo. Virology, 2011, 409: 156-162. SCI, IF= 3.353
17.Cheng XF, Wu J, Ma X, Fu H, and Wu X. First report of citrus tristeza virus in Citrus changshanensis cv. Huyou in Zhejiang, China. Journal of plant Pathology, 2011, 93(s4): 68. SCI
18.Wu X, Wu J, and Cheng XF*. First report of natural infection of broad bean wilt virus-2 on Lactuca indica. Journal of Plant Pathology, 2010, 92(s4): 119. SCI
19.Cheng XF, Dong J, Fang Q, Ding M, McBeatch J and Zhang Z. Detection of impatiens necrotic spot virus infecting Phalaenopsis in Yunnan. Journal of Plant Pathology, 2010, 92(2): 545. SCI
20.武晓云,程晓非,张仲凯,桂富荣,李正跃.西花蓟马(Frankliniella occidentalis) rDNA ITS2和COⅠ基因5´末端序列的克隆及分析.浙江大学学报(农业与生命科学版),2009,35(4):355-364.
21.Dong J+, Cheng X+, Yin Y, Fang Q, Ding M, Li T, Zhang L, Su X, McBeath J, and Zhang Z. Characterization of tomato zonate spot virus, a new tospovirus species in China. Archives of Virology, 2008, 153(5): 855-864. (+Co-first authors) SCI, IF=2.058
22.程晓非,董家红,方琦,李婷婷,丁铭,张仲凯.从云南蝴蝶兰上检测到番茄斑萎病毒属病毒. 植物病理学报,2008