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个人简介

顾成波,男,汉族,1975年出生,副教授、博士。1999年6月毕业于东北农业大学,获得农学学士学位,2003年毕业于东北农业大学,获得农学硕士学位,2006年6月毕业于中国农业大学,获得理学博士学位,并于同年到东北林业大学任教,2008年8月至2011年5月浙江海正药业集团博士后工作站从事博士后研究,2015年9月至2016年9月国家公派访问学者赴美国加州大学戴维斯分校进行访学交流。主要从事(1)天然药食植物资源、微生物资源研究与利用;(2)植物-微生物相互作用(3)微生物天然产物药物与微生物肥料开发与利用;(4)植物(微生物)次生代谢产物及其生理生态效应。发表学术论文50余篇。 主持课题情况: 1.“十三五”国家重点研发计划子课题,2016YFD0600805-01-02,木豆叶中牡荆苷的高效提纯及其功能制剂制备,2016-2020 2. 黑龙江省自然科学基金,C2017004,木豆促进成骨细胞增殖特异内生真菌G6和Y3的鉴定及其活性代谢产物研究,2017-2020 3. 浙江海正药业股份有限公司横向课题,43211006,水溶性牡荆苷冻干粉制备与功能检测,2011-2014 4. 国家公益性行业林业科研专项子课题,20120460113-01-11,牡荆苷对股骨头坏死的治疗作用研究,2012-2014 5.哈尔滨市科技创新人才专项资金项目,DL09BA20,2011-2013 6.主持中央高校基本科研业务专项资金2项 获奖科技成果: 1. 黑龙江省科学技术发明一等奖, 木豆资源功能活性成分高值化加工利用关键技术及产业化应用, 2017年(第五名) 2. 黑龙江省技进步三等奖, 北药黄芪生态培育与高效加工技术集成, 2014年(第三名) 3. 黑龙江省科学技术发明一等奖, 红豆杉中紫杉烷类活性成分高效诱导、分离纯化和多西紫杉醇半合成, 2008年(第三名) 4. 梁希林业科学技术奖三等奖,红豆杉中紫杉烷类活性成分高效诱导、分离纯化和多西紫杉醇半合成,2009年(第三名)

近期论文

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1.Gu CB, Ma H, Ning WJ, Niu LL, Han HY, Yuan XH, Fu YJ. Characterization, culture medium optimization and antioxidant activity of an endophytic vitexin-producing fungus Dichotomopilus funicola Y3 from pigeon pea [Cajanus cajan (L.) Millsp.]. Journal of applied microbiology, 2018,125(4): 1054-1065 2.Chengbo Gu, Linan Fu, Xiaohan Yuan and Zhiguo Liu.Promoting effect of pinostrobin on the proliferation, differentiation, and mineralization of murine pre-osteoblastic MC3T3-E1 Cells. Molecules 2017, 22, 1735 3. Chengbo Gu, Ziwei Liu, Xiaohan Yuan, Wang Li, Yuangang Zu and Yujie Fu. Preparation of vitexin nanoparticles by combining the antisolvent precipitation and high pressure homogenization approaches followed by lyophilization for dissolution rate enhancement. Molecules 2017, 22, 2038 4.Xiao-Han Yuan, Li-Nan Fu, Cheng-Bo Gu*, Yan-Dong Zhang, Yu-Jie Fu. Microwave-assisted extraction and antioxidant activity of vaccarin from the seeds of Vaccaria segetalis. Separation and Purification Technology. 2014:133(7), 91–98 5.Tong Wang, Cheng-Bo Gu, Sui-Xin Wang, Ping Kou, Jiao Jiao, Yu-Jie Fu. Simultaneous extraction, transformation and purification of psoralen from fig leaves using pH-dependent ionic liquid solvent based aqueous two-phase system. Journal of Cleaner Production 2018,172:827-836 6. Fei-Yue M, Cheng-Bo Gu, Chun-Ying Li, Meng Luo, Wei Wang, Yuan-Gang Zu, Ji Li, Yu-Jie Fu. Microwave-assisted aqueous two-phase extraction of isoflavonoids from Dalbergia odorifera T. Chen leaves. Separation and Purification Technology, 2013,115, 136-144 7. Li J, Zu YG, Luo M, Gu CB, Zhao CJ, Thomas E, Fu YJ*. Aqueous enzymatic process assisted by microwave extraction of oil from yellow horn (Xanthoceras sorbifolia Bunge.) seed kernels and its quality evaluation.Food Chemistry,2013 ,138(4):2152-2158 8. Qing-Yan Gai, Jiao Jiao, Meng Luo, Wei Wang, Cheng-Bo Gu, Yu-Jie Fu*, Wei Ma. Tremendous enhancements of isoflavonoid biosynthesis, associated gene expression and antioxidant capacity in Astragalus membranaceus hairy root cultures elicited by methyl jasmonate. Process Biochemistry, 2016,51(5):642-649 9. Li J, Peng X, Luo M, Zhao CJ, Gu CB, Zu YG, Fu YJ*, Biodiesel production from Camptotheca acuminata seed oil catalyzed by novel Brönsted-Lewis acidic ionic liquid. Applied Energy, 2014, 115, 438-444 10. Sun Y, Gao C, Luo M, Wang W, Gu C, Zu Y, Li J, Efferth T, Fu Y. Aspidin PB, a phloroglucinol derivative, induces apoptosis in human hepatocarcinoma HepG2 cells by modulating PI3K/Akt/GSK3β pathway. Chemico-biological interactions, 2013, 201(1-3):1-8 11. Yu Kong, Zuo-Fu Wei, Yu-Jie Fu, Cheng-Bo Gu, Chun-Jian Zhao, Xiao-Hui Yao,Thomas Efferth. Negative-pressure cavitation extraction of cajaninstilbene acid and pinostrobin from pigeon pea [Cajanus cajan (L.) Millsp.] leaves and evaluation of antioxidant activity. Food Chemistry 2011,128:596–605 12. Xia Liu, Yuangang Zu, Yujie Fu, Liping Yao, Chengbo Gu, Wei Wang ,Thomas Efferth. Antimicrobial activity and cytotoxicity towards cancer cells of Melaleuca alternifolia (tea tree) oil. European Food Research And Technology.2009, 229:247–253 13.Ying Zhang, Meng Luo, Yuangang Zu, Yujie Fu, Chengbo Gu, Wei Wang, Liping Yao, Thomas Efferth. Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway. Chemico-Biological Interactions 2012,199:129–136 14.顾成波,马慧,宁文娟,李旺,韩海燕,付玉杰,祖元刚,袁肖寒.牡荆苷纳米混悬剂在大鼠体内的药代动力学初步研究.辽宁中医杂志,2019,46(5):1027-1029 15 顾成波,蔡曼,袁肖寒,祖元刚.牡荆苷的植物资源及药理作用研究进展.中国中药杂志, 2015, 40 (3):382-387

学术兼职

现任东北林业大学林业生物制剂教育部工程研究中心副主任,黑龙江省植物学会理事。

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