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招生方向 微纳生物分析与材料 纳米药物 微纳米制造 教育背景 2006-09--2010-12 美国范德堡大学 博士 工作简历 2011-03~现在, 国家纳米科学中心, 助理研究员,副研究员,研究员 2006-09~2010-12,美国范德堡大学, 博士 教授课程 生物芯片技术前沿 专利成果 ( 1 ) 一种微流控免疫检测分析芯片及其分析仪器, 2015, 第 3 作者, 专利号: ZL 201410409347 ( 2 ) 一种微流控芯片、使用其合成功能纳米颗粒的方法及应用, 2015, 第 3 作者, 专利号: ZL 201410114187 ( 3 ) 一种含有纳米微晶纤维素的AKD 施胶剂、制备方法及其用途, 2017, 第 4 作者, 专利号: ZL 201410670888.X ( 4 ) 基于移液器枪头的集样品预处理和扩增于一体的核酸分析系统及其应用, 2017, 第 3 作者, 专利号: ZL 201510012723.8 ( 5 ) 一种微流控芯片及使用其制备纳米胶囊的方法, 2017, 第 4 作者, 专利号: ZL 201410854624.X ( 6 ) 一种基于纤维载体的固定化漆酶及其制备方法和应用, 2017, 第 3 作者, 专利号: ZL 201410112485.3 ( 7 ) 一种核酸等温扩增反应系统及其制备方法和应用, 2016, 第 3 作者, 专利号: ZL 201210167147.0 ( 8 ) 用于分离去除血液中循环肿瘤细胞和血小板的系统及方法, 2016, 第 3 作者, 专利号: ZL 201410225082.X ( 9 ) 一种双螺旋微流控芯片, 2016, 第 3 作者, 专利号: ZL 201410345305.6 ( 10 ) 一种自动化单抗筛选机, 2016, 第 3 作者, 专利号: ZL 201410502957.6 ( 11 ) 一种纳米微晶纤维素涂料、制备方法及使用该涂料的涂布纸, 2016, 第 5 作者, 专利号: ZL 201410677383.6 ( 12 ) 一种基于界面效应的微纳颗粒分离系统, 2020, 第 1 作者, 专利号: ZL 201710418064.7 ( 13 ) 一种微流控芯片、手动离心装置及核酸检测方法, 2017, 第 1 作者, 专利号: 201710884038.3 ( 14 ) 核酸检测试剂混合添加装置, 2018, 第 1 作者, 专利号: 201810585901.X ( 15 ) 核酸检测芯片, 2018, 第 1 作者, 专利号: 201810583631.9 ( 16 ) 核酸检测方法, 2018, 第 1 作者, 专利号: 201810585803.6 ( 17 ) 基于微流控芯片的核酸检测装置, 2018, 第 1 作者, 专利号: 201810585805.5 ( 18 ) 基于多种核酸反应的核酸检测芯片, 2018, 第 1 作者, 专利号: 201810585842.6 ( 19 ) 基于热泳细胞外囊泡检测的结直肠癌检测系统及方法, 2018, 第 1 作者, 专利号: 201811321673.1 ( 20 ) 结直肠癌检测装置, 2018, 第 1 作者, 专利号: 201821828985.7 ( 21 ) 基于热泳细胞外囊泡检测的胃癌检测系统及方法, 2018, 第 1 作者, 专利号: 201811321680.1 ( 22 ) 胃癌检测装置, 2018, 第 1 作者, 专利号: 201821828984.2 ( 23 ) 基于热泳细胞外囊泡检测的肝癌检测系统及方法, 2018, 第 1 作者, 专利号: 201811321676.5 ( 24 ) 肝癌检测装置, 2018, 第 1 作者, 专利号: 201821828989.5 ( 25 ) 基于热泳细胞外囊泡检测的肺癌检测系统及方法, 2018, 第 1 作者, 专利号: 201811321678.4 ( 26 ) 肺癌检测装置, 2018, 第 1 作者, 专利号: 201821828990.8 ( 27 ) 基于热泳细胞外囊泡检测的乳腺癌检测系统及方法, 2018, 第 1 作者, 专利号: 201811321129.7 ( 28 ) 乳腺癌检测装置, 2018, 第 1 作者, 专利号: 201821829002.1 ( 29 ) 基于热泳对PD-L1受体的检测系统及方法, 2018, 第 1 作者, 专利号: 201811321152.6 ( 30 ) 基于PD-L1受体的癌症检测装置, 2020, 第 1 作者, 专利号: ZL 201821829523.7 ( 31 ) 基于热泳对VEGF受体的检测系统及方法, 2018, 第 1 作者, 专利号: 201811321150.7 ( 32 ) VEGF受体检测装置, 2018, 第 1 作者, 专利号: 201821829001.7 ( 33 ) 基于热泳对EGFR受体的检测系统及方法, 2018, 第 1 作者, 专利号: 201811321208.8 ( 34 ) 基于EGFR受体癌症检测装置, 2018, 第 1 作者, 专利号: 201821829003.6 ( 35 ) 基于热泳细胞外囊泡检测的癌症检测系统, 2018, 第 1 作者, 专利号: 201821829521.8 ( 36 ) 基于利用化学发光的前列腺癌症检测装置, 2018, 第 1 作者, 专利号: 201821828999.9 ( 37 ) 基于热泳检测利用化学发光的前列腺癌症检测系统及方法, 2018, 第 1 作者, 专利号: 201811321681.6 ( 38 ) 基于热泳检测的前列腺癌症治疗方案选择评价方法及系统, 2018, 第 1 作者, 专利号: 201811321166.8 ( 39 ) 基于热泳细胞外囊泡的前列腺癌症复发监控系统及方法, 2018, 第 1 作者, 专利号: 201811321677.X ( 40 ) 基于热泳细胞外囊泡的前列腺癌病重程度检测系统及方法, 2018, 第 1 作者, 专利号: 201811321679.9 ( 41 ) 基于热泳细胞外囊泡检测的前列腺癌症检测装置, 2018, 第 1 作者, 专利号: 201821828998.4 ( 42 ) 基于热泳细胞外囊泡检测的前列腺癌检测系统及方法, 2018, 第 1 作者, 专利号: 201811321130.X ( 43 ) 基于界面效应的癌细胞分离装置, 2019, 第 1 作者, 专利号: ZL 201821174077.0 ( 44 ) 基于界面效应的癌细胞分离装置, 2018, 第 1 作者, 专利号: 201810819744.4 ( 45 ) 基于外泌体的癌症检测系统及方法, 2018, 第 1 作者, 专利号: 201810306611.7 ( 46 ) 基于外泌体的癌症检测系统及方法, 2018, 第 1 作者, 专利号: ZL 201820486575.2 ( 47 ) 基于微球载体的粒子检测系统及方法, 2018, 第 1 作者, 专利号: 201810306124.0 ( 48 ) 基于微球载体的粒子检测系统, 2018, 第 1 作者, 专利号: ZL 201820486040.5 ( 49 ) 微纳粒子检测系统及方法, 2018, 第 1 作者, 专利号: 201810306599.X ( 50 ) 微纳粒子检测系统及方法, 2018, 第 1 作者, 专利号: ZL 201820486046.2 ( 51 ) 使用微流控芯片合成生物膜纳米颗粒的方法及微流控芯片, 2019, 第 1 作者, 专利号: 201910799739.6 发表著作 Microfluidic devices for viral detection--Chapter15:Microfluidic devices for biomedical applications, Woodhead Publishing, 2013-11, 第 1 作者 科研项目 ( 1 ) 微流控芯片可控合成siRNA复合纳米材料及其应用, 主持, 国家级, 2015-01--2018-12 ( 2 ) 面向重大疾病治疗的纳米载体材料及诊断技术--血糖取样测量一体化的纳米微针芯片, 主持, 国家级, 2013-12--2016-11 ( 3 ) 中国科学院青年创新促进会, 主持, 部委级, 2016-01--2019-12 ( 4 ) 北京市科技新星计划, 主持, 省级, 2016-01--2018-12 ( 5 ) 分析化学, 主持, 国家级, 2017-01--2019-12 ( 6 ) 北京市科技新星计划-交叉学科合作, 主持, 省级, 2017-01--2018-12 ( 7 ) 针对功能杂化纳米结构的微流控精准合成及检测仪器研制, 主持, 部委级, 2019-01--2020-12 ( 8 ) 基于微流控热泳技术的早期乳腺癌细胞外囊泡蛋白及核酸分子的可视化检测, 主持, 国家级, 2020-01--2022-12 ( 9 ) 基于微纳生物技术的肿瘤液体活检, 主持, 部委级, 2019-09--2024-09 参与会议 (1)Microfluidics-enabled cancer diagnostics 2019-07-29 (2)Microfluidics-Enabled Cancer Diagnosis 2019-07-08 (3)Micro_x001d_uidics for Nanomedicine Discovery 2018-10-18 (4)Microfluidics for nanomedicine discovery 2018-10-15

近期论文

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(1) ATP-responsive Mitochondrial Probes for Monitoring Metabolic Processes of Glioma Stem Cells in a 3D Model, Chemical Science, 2020, 通讯作者 (2) Enantiomorphic Microvortex-Enabled Supramolecular Sensing of Racemic Amino Acids by using Achiral Building Blocks, Angewandte Chemie International Edition, 2020, 通讯作者 (3) Thermophoretic Detection of Exosomal microRNAs by Nanoflares, Journal of the American Chemical Society, 2020, 通讯作者 (4) Improving Tumor Targeting of Exosomal Membrane-Coated Polymeric Nanoparticles by Conjugation with Aptamers, ACS Applied Bio Materials, 2020, 通讯作者 (5) Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers, Nature Biomedical Engineering, 2019, 通讯作者 (6) λ-DNA- and aptamer-mediated sorting and analysis of extracellular vesicles, Journal of the American Chemical Society, 2019, 通讯作者 (7) Lipid nanovesicles by microfluidics: manipulation, synthesis and drug delivery, Advanced Materials, 2019, 通讯作者 (8) Microfluidic analysis of circulating tumor cells and tumor-derived extracellular vesicles, Trends in Analytical Chemistry, 2019, 通讯作者 (9) Manipulation of bio-micro/nanoparticles in non-Newtonian microflows, Microfluidics and Nanofluidics, 2019, 通讯作者 (10) Microfluidic Sonication to Assemble Exosome Membrane-Coated Nanoparticles for Immune Evasion-Mediated Targeting, Nano Letters, 2019, 通讯作者 (11) Microfluidic Methods for Fabrication and Engineering of Nanoparticle Drug Delivery Systems, ACS Applied Bio Materials, 2019, 通讯作者 (12) Real-time characterization of negative air ions-induced decomposition of indoor organic contaminants by mass spectrometry, Chemical Communications, 2018, 第 4 作者 (13) Label-Free Isolation of Rare Tumor Cells from Untreated Whole Blood by Interfacial Viscoelastic Microfluidics, Lab on a Chip, 2018, 通讯作者 (14) Control over the emerging chirality in supramolecular gels and solutions by chiral microvortices in milliseconds, Nature Communications, 2018, 第 1 作者 (15) Hand-powered Centrifugal Microfluidic Platforms Inspired by a Spinning Top for Sample-to-Answer Diagnostics of Nucleic Acids, Lab on a Chip, 2018, 通讯作者 (16) Micro/nanofluidics-enabled single-cell biochemical analysis, Trends in Analytical Chemistry, 2018, 通讯作者 (17) Integrated Microfluidic Platform with Multiple Functions to Probe the Tumor-endothelial Cell Interaction, Analytical Chemistry, 2017, 通讯作者 (18) Microfluidic Co-flow of Newtonian and Viscoelastic Fluids for High-resolution Separation of Microparticles, Lab on a Chip, 2017, 通讯作者 (19) Point-of-Care-Testing of Nucleic Acids by Microfluidics, Trends in Analytical Chemistry, 2017, 通讯作者 (20) Stimulus-Responsive Plasmonic Chiral Signals of Gold Nanorods Organized on DNA Origami, Nano Letters, 2017, 通讯作者 (21) Field-free Isolation of Exosomes from Extracellular Vesicles by Microfluidic Viscoelastic Flows, ACS Nano, 2017, 通讯作者 (22) Hand-powered Centrifugal Microfluidic Platforms Inspired by a Spinning Top for Sample-to-Answer Diagnostics of Nucleic Acids, Lab on a Chip, 2017, 通讯作者 (23) One-Step Microfluidic Synthesis of Nanocomplex with Tunable Rigidity and Acid- Switchable Surface Charge for Overcoming Drug Resistance, Small, 2017, 通讯作者 (24) An Automated and Portable Microfluidic Chemiluminescent Immunoassay for Quantitative Detection of Biomarkers, Lab Chip, 2017, 通讯作者 (25) Double Enzymes-mediated Bioluminescent Sensor for Quantitative and Ultra-sensitive Point-of-care Testing, Anal. Chem., 2017, 通讯作者 (26) Streptavidin-biotin-peroxidase nanocomplex-amplified microfluidics immunoassays for simultaneous detection of inflammatory biomarkers, Analytica Chimica Acta, 2017, 通讯作者 (27) Investigation of Carbon Deposition Induced by Pyrolytic Decomposition of Ethylene, RSC Adv., 2017, 通讯作者 (28) Reference Channel-based Microfluidic Resistance Sensing For Single Yeast Cell Volume Growth measurement, Microfluidics and Nanofluidics, 2017, 第 1 作者 (29) Quantitative Detection of MicroRNA in One Step via Next Generation Magnetic Relaxation Switch Sensing, ACS Nano, 2016, 通讯作者 (30) A Non-specific Organelle-targeting Strategy with Core-Shell Nano-particles of Varied Lipid Components/Ratios, Anal. Chem., 2016, 通讯作者 (31) Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning, Anal. Chem., 2016, 通讯作者 (32) A Dual-readout Chemiluminescent Gold Lateral Flow Test for Multiplex and Ultrasensitive Detection of Disease Biomarkers in Real Samples, Nanoscale, 2016, 第 1 作者 (33) Nanocrystalline Cellulose-Assisted Generation of Silver Nanoparticles for Non-enzymatic Glucose Detection and Antibacterial Agent, Biomacromolecules, 2016, 通讯作者 (34) A Microfluidic Indirect Competitive Immunoassay for Multiple and Sensitive Detection of Testosterone in Serum and Urine, Analyst, 2016, 通讯作者 (35) Rotation-Facilitated Rapid Transport of Nanorods in Mucosal Tissues, Nano Lett., 2016, 第 7 作者 (36) One-step Detection of Pathogens and Cancer Biomarkers by Naked Eyes Based on Aggregation of Immunomagnetic Beads, Nanoscale, 2016, 第 3 作者 (37) A Generalized Formula for Inertial Lift on a Sphere in Microchannels, Lab Chip, 2016, 第 3 作者 (38) The Biocompatibility Evaluation of Iron Oxide Nanoparticles Synthesized by a One Pot Process for Intravenous Iron Supply, RSC Adv., 2016, 第 8 作者 (39) Nanocrystalline Cellulose Improves the Biocompatibility and Reduces the Wear Debris of Ultrahigh Molecular Weight Polyethylene via Weak Binding, ACS Nano, 2016, 通讯作者 (40) Microfluidics-mediated assembly of functional nanoparticles for cancer-related pharmaceutical applications, Nanoscale, 2016, 通讯作者 (41) High-throughput sample-to-answer detection of DNA/RNA in crude samples within functionalized micro-pipette tips, Biosens. Bioelectron., 2016, 通讯作者 (42) Microfluidic synthesis of rigid nanovesicles for hydrophilic reagents delivery, Angew. Chem. Int. Ed., 2015, 通讯作者 (43) Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake, Adv. Mater., 2015, 第 1 作者 (44) Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell Nanoparticle Interaction, ACS Nano, 2015, 通讯作者 (45) One-Step Detection of Pathogen and Virus Combining Magnetic Relaxation Switching and Magnetic Separation, ACS Nano, 2015, 通讯作者 (46) Barcoded microchips for biomolecular assays, Anal. Chem., 2015, 通讯作者 (47) Label-Free Isolation and mRNA Detection of Circulating Tumor Cells from Patients with Metastatic Lung Cancer for Disease Diagnosis and Monitoring Therapeutic Efficacy, Anal. Chem., 2015, 通讯作者 (48) Multiplexed microfluidic blotting of proteins and nucleic acids by parallel, serpentine microchannels, Lab Chip, 2015, 通讯作者 (49) Inertial focusing of spherical particles in rectangular microchannels over a wide range of Reynolds numbers, Lab Chip, 2015, 通讯作者 (50) Surface modification of nano silica on ligament advanced reinforcement system for accelerated bone formation: primary human osteoblasts testing in vitro and animal testing in vivo, Nanoscale, 2015, 通讯作者 (51) Microfluidic based high throughput synthesis of lipid-polymer hybrid nanoparticles with tunable diameters, Biomicrofluidics, 2015, 通讯作者 (52) oint-of-care biochemical assays using gold nanoparticle-implemented microfluidics, Chem. Soc. Rev., 2014, 第 1 作者 (53) Point-of-Care Multiplexed Assays of Nucleic Acids Using Microcapillary-based Loop-Mediated Isothermal Amplification, Anal. Chem., 2014, 通讯作者 (54) Integrated Microcapillary for Sample-to-Answer Nucleic Acid Pretreatment, Amplification, and Detection, Anal. Chem., 2014, 通讯作者 (55) Mesosilica-coated ultrafine fibers for highly efficient laccase encapsulation, Nanoscale, 2014, 通讯作者 (56) A microfluidic tubing method and its application for controlled synthesis of polymeric nanoparticles, Lab Chip, 2014, 通讯作者 (57) Recent advances in electrospinning technology and biomedical applications of electrospun fibers, Journal of Materials Chemistry B, 2014, 通讯作者 (58) Inertial migration of deformable droplets in a microchannel, Physics of Fluids, 2014, 通讯作者

学术兼职

2019-12-31-2022-12-30,Analytical Chemistry, the Early Career Board 2018-01-01-今,《中国科学:化学》(Science China Chemistry), 青年工作委员会委员 2017-12-01-今,中国抗癌协会肿瘤标志物委员会胞外体暨外泌体专家委员会, 委员 2017-10-01-今,中国医学装备协会检验医学分会, 委员

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