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个人简介

陈春英,国家纳米科学中心研究员、博士生导师。国家杰出青年科学基金获得者,中国科学院纳米生物效应与安全性重点实验室副主任,先后担任国家重点研发计划“纳米科技”重点专项、“纳米前沿”重点专项首席科学家。 1996年在华中科技大学获得博士学位,之后在中科院高能物理研究所、瑞典卡罗林斯卡大学诺贝尔医学生物化学研究所从事博士后研究工作。2002年在中科院高能所纳米生物效应与安全实验室,任课题组长。2006年6月加入国家纳米科学中心。先后主持科技部国家重点研发计划“纳米科技”重点专项和“纳米前沿”重点专项、国家自然科学基金委国家重大科研仪器研制项目、国家自然科学基金委重大研究计划重点支持项目、欧盟第六、第七框架计划(EU-FP6&FP7 )、欧盟“地平线2020”计划、德国联邦教育与研究部合作项目、丹麦战略研究委员会项目、丹麦科技与创新局项目、国际原子能机构协调研究计划(IAEA)等多项国内与国际合作项目。

研究领域

纳米蛋白冠的分析方法及其化学生物学效应;纳米材料生物体内行为的检测方法与机制;纳米佐剂与递送系统

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Guofang Zhang, Yalin Cong, Feng-Liang Liu, Jiufeng Sun, Jiantian Zhang, Guoli Cao, Lingqiang Zhou, Wenjie Yang, Qingle Song, Fangjun Wang, Ke Liu, Jing Qu, Jing Wang, Min He, Shun Feng, Didar Baimanov, Wei Xu, Rong-Hua Luo, Xin-Yan Long, Shumin Liao, Yunping Fan, Yu-Feng Li, Bai Li, Ximing Shao, Guocheng Wang, Lijing Fang, Huaiyu Wang, Xue-Feng Yu, Yan-Zhong Chang, Yuliang Zhao, Liang Li, Peng Yu, Yong-Tang Zheng*, Diana Boraschi, Hongchang Li*, Chunying Chen*, Liming Wang*, Yang Li*. A nanomaterial targeting the spike protein captures SARS-CoV-2 variants and promotes viral elimination. Nature Nanotechnology, 2022, https://doi.org/10.1038/s41565-022-01177-2. Mingjing Cao, Rong Cai, Lina Zhao, Mengyu Guo, Liming Wang, Yucai Wang, Lili Zhang, Xiaofeng Wang, Haodong Yao, Chunyu Xie, Yalin Cong, Yong Guan, Xiayu Tao, Yaling Wang, Shaoxin Xu, Ying Liu, Yuliang Zhao, Chunying Chen*. Molybdenum Derived from Nanomaterials Incorporates into Molybdenum Enzymes and Affects Their Activities in vivo. Nature Nanotechnology, 2021, 16: 708-716. Muhammad Ovais#, Sudip Mukherjee#, Arindam Pramanik, Devlina Das, Anubhab Mukherjee, Abida Raza, Chunying Chen*. Designing Stimuli-Responsive Upconversion Nanoparticles that Exploit the Tumor Microenvironment. Advanced Materials, 2020, 2000055. pdf Yantao Li#, Jiaming Liu#, Zuochao Wang#, Jun Jin, Yaling Liu*, Chunying Chen*, Zhiyong Tang*. Optimizing Energy Transfer in Nanostructures Enables In Vivo Cancer Lesion Tracking via Near-Infrared Excited Hypoxia Imaging. Advanced Materials, 2020, 1907718. pdf Yang Cai#, Dongqi Ni#, Wenyu Cheng, Chendong Ji, Yaling Wang, Klaus Müllen, Zhiqiang Su*, Ying Liu, Chunying Chen*, Meizhen Yin*. Enzyme-Triggered Disassembly of Perylene Monoimide-based Nanoclusters for Activatable and Deep Photodynamic Therapy. Angewandte Chemie International Edition, 2020, 59(33): 14014-14018. pdf Mengyu Guo#, Xiao Zhang#, Jing Liu*, Fene Gao, Xiaolei Zhang, Xuhao Hu, Bo Li, Xu Zhang, Huige Zhou, Ru Bai, Yaling Wang, Jiayang Li, Ying Liu, Zhanjun Gu*, Chunying Chen*. Few-Layer Bismuthene for Checkpoint Knockdown Enhanced Cancer Immunotherapy with Rapid Clearance and Sequentially Triggered One-for-All Strategy. ACS Nano 2020, 14: 15700-15713. pdf Ibrahim Javed#, Xuejing Cui#, Xiaoyu Wang, Monika Mortimer, Nikolaos Andrikopoulos, Yuhuan Li, Thomas P. Davis, Yuliang Zhao, Pu Chun Ke*, Chunying Chen*. Implications of the Human Gut-Brain and Gut-Cancer Axes for Future Nanomedicine. ACS Nano, 2020, 14: 14391-14416. pdf Didar Baimanov, Junguang Wu, Runxuan Chu, Rong Cai, Bing Wang, Mingjing Cao, Ye Tao, Jiaming Liu, Mengyu Guo, Jing Wang, Xia Yuan, Chendong Ji, Yuliang Zhao, Weiyue Feng*, Liming Wang*, Chunying Chen*. Immunological Responses Induced by Blood Protein Coronas on Two-Dimensional MoS2 Nanosheets. ACS Nano, 14(5): 5529-5542.pdf Jiaming Liu#, Liming Wang#, Xiaomei Shen, Xingfa Gao*, Yanhuan Chen, Huibiao Liu*, Ying Liu, Dongtao Yin, Yang Liu, Wei Xu, Rong Cai, Min You, Mengyu Guo, Yaling Wang, Jiayang Li, Yuliang Li, Chunying Chen*. Graphdiyne-templated palladium-nanoparticle assembly as a robustoxygen generator to attenuate tumor hypoxia. Nano Today, 2020, 34: 100907. Pengyu Chen#, Feng Ding#, Rong Cai#, Ibrahim Javed, Wen Yang, Zhenzhen Zhang, Yuhuan Li, Thomas P. Davis, Pu Chun Ke*, Chunying Chen*. Amyloidosis inhibition, a new frontier of the protein corona. Nano Today, 2020, 35: 100937. pdf Rong Cai#, Jiayu Ren#, Yinglu Ji, Yaling Wang, Ying Liu, Zhiqiang Chen, Zeinab Farhadi Sabet, Xiaochun Wu, Iseult Lynch, Chunying Chen*. Corona of Thorns: The Surface Chemistry-Mediated Protein Corona Perturbs the Recognition and Immune Response of Macrophages. ACS Applied Materials & Interfaces, 2020, 12, 1997-2008. pdf Xuejing Cui#, Lin Bao#, Xiaoyu Wang, Chunying Chen*. The Nano-Intestine Interaction: Understanding the Location-Oriented Effects of Engineered Nanomaterials in the Intestine. Small, 2020, 1907665. pdf Shuang Zhu, Lele Li, Zhanjun Gu*, Chunying Chen*, Yuliang Zhao*. 15 Years of Small: Research Trends in Nanosafety. Small, 2020, 16: 2000980. pdf Chunying Chen, David T. Leong, Iseult Lynch*. Rethinking Nanosafety: Harnessing Progress and Driving Innovation (Editorial). Small, 2020, 16: 2002503. pdf Chunying Chen*, David Leong*, Iseult Lynch*. Rethinking Nanosafety Part II: Leveraging Progress to Pioneer New Approaches and Solutions (Editorial). Small 2020, 16: 2004934. pdf Jie Ding#, Yong Guan#, Yalin Cong, Liang Chen, Yu-Feng Li, Lijuan Zhang, Lili Zhang, Jian Wang, Ru Bai, Yuliang Zhao, Chunying Chen, Liming Wang*. Single-Particle Analysis for Structure and Iron Chemistry of Atmospheric Particulate Matter. Analytical Chemistry, 2020, 92, 975-982. pdf Wenjiao Fu, Zeinab Farhadi Sabet, Jiaming Liu, Min You, Huige Zhou, Yaling Wang, Yuan Gao, Jiayang Li*, Xiaomei Ma*, Chunying Chen*. Metal ions modulation of the self-assembly of short peptide conjugated nonsteroidal anti-inflammatory drugs (NSAIDs). Nanoscale, 2020, 12(14): 7960-7968. pdf Jinglong Tang#, Ruirui Zhang#, Mengyu Guo, Huige Zhou, Yuliang Zhao, Ying Liu, Yan Wu*, Chunying Chen*. Gd-metallofullerenol drug delivery system mediated macrophage polarization enhances the efficiency of chemotherapy. Journal of Controlled Release, 2020, 320: 293-303. pdf Xiaoyu Wang#, Xuejing Cui#, Yuliang Zhao, Chunying Chen*. Nano-bio interactions: the implication of size-dependent biological effects of nanomaterials. Science China Life Sciences, 2020, 63(8): 1168-1182. pdf Zilong Zhao#, Yaling Wang#, Liping Qiu#, Ting Fu, Yu Yang, Ruizi Peng, Mengyu Guo, Lichun Mao, Chunying Chen*, Yuliang Zhao, Weihong Tan*. New insights from chemical biology: molecular basis for transmission, diagnosis and therapy of SARS-CoV-2. CCS Chemistry, 2020, 2: 1501-1528. pdf Tao Liu#, Ru Bai#, Huige Zhou#, Rongqi Wang, Jing Liu, Yuliang Zhao, Chunying Chen*. The effect of size and surface ligands of iron oxide nanoparticles on blood compatibility. RSC Advances, 2020, 10(13): 7559-7569. pdf Muhammad Ovais#, Susheel Kumar Nethi#, Saleem Ullah, Irshad Ahmad, Sudip Mukherjee, Chunying Chen*. Recent advances in the analysis of nanoparticle-protein coronas. Nanomedicine, 2020, 15(10): 1037-1061. pdf

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