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个人简介

2019-至今,北京师范大学化学学院,教授 2016-2018 年,美国University of Florida,博士后(导师:谭蔚泓教授) 2010-2016 年,美国University of Massachusetts Amherst,博士 (导师:Vincent M. Rotello教授)

研究领域

分析化学;脑神经分析化学;纳米生物化学;化学生物学 本课题组将主要围绕脑神经分析化学领域展开工作。以活动物脑内神经化学信号分子为对象,通过创新分析化学原理和方法,实现对于神经生理和病理过程中神经化学信号的精准测量。主要包括以下三方面工作:1)构建具有高选择性和高稳定性的活体识别元件;2)发展多通道活体分析方法;3)探索神经信号分子在大脑活动尤其是神经退行性疾病过程的作用机制。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Hou, H.; Jin, Y.; Wei, H.; Ji, W.; Xue, Y.; Hu, J.; Zhang, M.; Jiang, Y.;* and Mao, L.* A Generalizable and Noncovalent Strategy of Interfacing Aptamers with Microelectrode for Selective Sensing of Neurotransmitter In Vivo, Angewandte Chemie International Edition, 2020, 59, 18996-19000. Jin, J.; Ji, W.; Li, L.; Zhao, G.; Wu, W.; Wei, H.; Ma, F.; Jiang, Y.;* and Mao, L.* Electrochemically Probing Dynamics of Ascorbate during Cytotoxic Edema in Living Rat Brain, Journal of the American Chemical Society, 2020, https://dx.doi.org/10.1021/jacs.0c09011 Zhou, M.;# Jiang, Y.;# Wang, G.; Wu, W.; Chen, W.; Yu, P.; Lin, Y.; Mao, J.; and Mao, L. Single-atom Ni-N4 Provides A Robust Cellular NO Sensor, Nature Communications, 2020, 11, 3188. (# Equal contribution) Xiao, T.; Wang, Y.; Wei, H.; Yu, P.; Jiang, Y.;* and Mao, L.* Electrochemical Monitoring of Propagative Fluctuation of Ascorbate in the Live Rat Brain during Spreading Depolarization, Angew. Chem. Int. Ed., 2019, 58, 6616–6619. Liang, C.; Chang, J.; Jiang, Y.;*, Liu, J.; Mao, L.; and Wang, M.* Selective RNA Interference and Gene Silencing using Reactive Oxygen Species-responsive Lipid Nanoparticles, Chem. Commun., 2019, 55, 8170-8173. Zhao, L.;# Jiang, Y.;# Wei, H.; Jiang, Y.; Ma, W.; Zheng, W.; Cao, A. M.; and Mao, L. In Vivo Measurement of Calcium Ion with Solid-State Ion-Selective Electrode by Using Shelled Hollow Carbon Nanospheres as Transducing Layer, Anal. Chem., 2019, 91, 4421-4428. (# Equal contribution) Jiang, Y,; Pan, X.; Chang, J.; Niu, W. J.; Hou, W. J.; Kuai, H.; Zhao, Z.; Liu, J.; Wang, M.; and Tan, W. Supramolecularly Engineered Circular Bivalent Aptamer for Enhanced Functional Protein Delivery, J. Am. Chem. Soc., 2018, 140, 6780-6784. Jiang, Y.; Shi, M.; Liu, Y.; Wan, S.; Cui, C.; Zhang, L.; and Tan, W. Aptamer/AuNP Biosensor for Colorimetric Profiling of Exosomal Proteins, Angew. Chem. Int. Ed., 2017, 56, 11916-11920. Jiang, Y.; Wang, M.; Hardie, J.; Tonga, G. Y.; Ray, M.; Xu, Q. B.; and Rotello, V. M. Chemically Engineered Nanoparticle-Protein Interface for Real Time Cellular Oxidative Stress Monitoring, Small 2016, 12, 3775-3779. Jiang, Y.; Tang, R.; Duncan, B.; Jiang, Z. W.; Yan, B.; Mout, R.; and Rotello, V. M. Direct Cytosolic Delivery of siRNA Using Nanoparticle Stabilized Nanocapsules, Angew. Chem. Int. Ed., 2015, 54, 506-510.

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