个人简介

UA CoS Distinguished Career Teaching Award, 2009 UA CoS Innovation in Teaching Award, 1995 IBM Paul J Flory Fellow, 1990-1991 National Institutes of Health Postdoctoral Fellow, 1981-1983

研究领域

Organic/Bioorganic/Materials and Polymer Chemistry/Synthesis/Synthetic Methods Development

The ability to synthesize molecules is of fundamental importance and at the core of advances in every technological field. The Mash Group uses the science and art of synthesis to solve chemical problems in areas such as biology and materials science.

近期论文

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Elshan, N. G. R. D.; Patek, R.; Vagner, J.; Mash, E. A. Anal. Biochem. 2014, 464, 24-29. "Spectrophotometric Determination and Removal of Unchelated Europium Ions from Solutions Containing Eu-Diethylenetriaminepentaacetic Acid Chelate-Peptide Conjugates." Alleti, R.; Vagner, J.; Dehigaspitiya, D. C.; Moberg, V. E.; Elshan, N. G. R. D.; Tafreshi, N. K.; Brabez, N.; Weber, C. S.; Lynch, R. M.; Hruby, V. J.; Gillies, R. J.; Morse, D. L.; Mash, E. A. Bioorg. Med. Chem. 2013, 21, 5029-5038. "Synthesis and Characterization of Time-resolved Fluorescence Probes for Evaluation of Competitive Binding to Melanocortin Receptors." Martinez, G. V.; Navath, S.; Sewda, K.; Rao, V.; Foroutan, P.; Alleti, R.; Moberg, V. E.; Ahad, A. M.; Coppola, D.; Lloyd, M. C.; Gillies, R. J.; Morse, D. L.; Mash, E. A. Bioorg. Med. Chem. Lett. 2013, 23, 2061-2064. "Demonstration of a Sucrose-derived Contrast Agent for Magnetic Resonance Imaging of the GI Tract." Navath, S.; Rao, V.; Woodford, R. T.; Midura-Kiela, M. T.; Ahad, A. M.; Alleti, R.; Kiela, P. R.; Mash, E. A. ACS Med. Chem. Lett. 2012, 3, 710-714. "Design, Synthesis, and Testing of a Molecular Truck for Colonic Delivery of 5-Aminosalicylic Acid." Rao, V.; Alleti, R.; Xu, L.; Tafreshi, N. K.; Morse, D. L.; Gillies, R. J.; Mash, E. A. Bioorg. Med. Chem. 2011, 19, 6474-6482. "A Sucrose-Derived Scaffold for Multimerization of Bioactive Peptides." Alleti, R.; Rao, V.; Xu, L.; Gillies, R. J.; Mash, E. A. J. Org. Chem. 2010, 75, 5895-5903. "A Solanesol-Derived Scaffold for Multimerization of Bioactive Peptides." Jagadish, B.; Guntle, G. P.; Zhao, D.; Gokhale, V.; Ozumerzifon, T. J.; Ahad, A. M.; Mash, E. A.; Raghunand, N. J. Med. Chem. 2012, 55, 10378-10386. "Redox-active Magnetic Imaging Contrast Agents: Studies with Thiol-bearing 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetracetic Acid Derivatives." Jagadish, B.; Brickert-Albrecht, G. L.; Nichol, G. S.; Mash, E. A.; Raghunand, N. Tetrahedron Lett. 2011, 52, 2058-2061. "On the Synthesis of 1,4,7-Tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane." Raghunand, N.; Guntle, G. P.; Gokhale, V.; Nichol, G. S.; Mash, E. A.; Jagadish, B. J. Med. Chem. 2010, 53, 6747-6757. "Design, Synthesis, and Evaluation of 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid-Derived, Redox-Sensitive Contrast Agents for Magnetic Resonance Imaging." Mash, E. A. CrystEngComm 2014, 16, 8620-8637. "Crystal Engineering with 1,4-Piperazine-2,5-diones." Wells, K.E.; Weatherhead, R. A.; Murigi, F. N.; Nichol, G. S.; Carducci, M. D.; Selby, H. D.; Mash, E. A. Cryst. Growth Des. 2012, 12, 5056-5068. "Organic Crystal Engineering with 1,4-Piperazine-2,5-diones. 8. Synthesis, Crystal Packing, and Thermochemistry of Piperazinediones Derived from 2-Amino-4,7-dialkoxyindan-2-carboxylic Acids." Ntirampebura, D.; Jagadish, B.; Nichol, G. S.; Carducci, M. D.; Dawson, A.; Rajapakshe, A.; Oliver, A. G.; Clegg, W.; Harrington, R. W.; Layne Jr., L.; Margolis, J. I.; Mash, E. A. Crystal Growth & Design 2008, 8, 3257-3270. "Organic Crystal Engineering with Piperazine-2,5-diones. 7. Crystal Packing of Piperazinediones Derived from 2-Amino-7-nitro-4-methoxyindan-2-carboxylic Acid." Murigi, F. N.; Nichol, G. S.; Mash, E. A. J. Org. Chem. 2010, 75, 1293-1296. "Synthesis of the Conformationally Constrained Tyrosine Analogs, (R)- and (S)-5-Hydroxy-2-aminoindan-2-carboxylic Acids." Weatherhead, R. A.; Carducci, M. D.; Mash, E. A. J. Org. Chem. 2009, 74, 8773-8778. "Synthesis of Conformationally Constrained Diaminodicarboxylic Acid Derivatives." Mash, E. A. (2012) "Synthetically Derived Chiral Auxiliaries: Uses of Derivatives of Non-Carbohydrate Aldehydes andKetones in Asymmetric Synthesis." In: Carreira E.M. and Yamamoto H. (eds.) Comprehensive Chirality, Volume 3, pp. 377-407; Amsterdam: Elsevier. Jones, I. W.; Lynn, M. A.; Mash, E. A. Tetrahedron 2009, 65, 10317-10322. "Conformational Analysis of Bridgehead-substituted Bicyclo[m.m.m]alkanes and Bicyclo[8.8.n]alkanes."