陆栋 - 中国科学院近代物理研究所 -

个人简介

工作简历 2019-08~现在, 中国科学院近代物理研究所生物物理室, 副主任 2016-05~2016-11,National Institute of Quantum and Radiological Science and Technology, Research Scholar 2012-12~现在, 中国科学院近代物理研究所, 副研究员 2009-11~2012-10,中国科学院近代物理研究所, 助理研究员 2006-06~2009-10,中国科学院近代物理研究所, 研究实习员社会兼职 2019-04-30-今,祁连学者教授 2018-01-01-今,International Dose-Response Society, member 2015-01-01-今,The Japanese Radiation Research Society, member

研究领域

酿酒酵母(Saccharomyces cerevisiae)具备真核生物的遗传学特性和原核生物的代谢特点，易于培养，且基因组和高等真核生物具有高度的同源性，是功能基因组学、现代分子生物学和细胞生物学研究的主要模式生物。本研究组利用电离辐射技术，利用基因组、转录组、脂质组等多组学方法分析真核生物DNA损伤修复的分子机制；结合辐射诱变和基因编辑技术创制微生物新菌种。主要研究兴趣 1）DNA损伤的修复途径与相应的调控机制； 2）电离辐射导致的亚细胞结构损伤的生化过程、调节因子和作用原理； 3）微生物新菌种创制

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

（1）Repair characteristics and time-dependent effects in response to heavy-ion beam irradiation in Saccharomyces cerevisiae: a comparison with X-ray irradiation, Applied Microbiology and Biotechnology, 2020-03, 通讯作者（2）The role of MiR-5094 as a proliferation suppressor during cellular radiation response via downregulating STAT5b, Journal of Cancer, 2020-02, 第 4 作者（3）Quantitative multi-omics analysis of the effects of mitochondrial dysfunction on lipid metabolism in Saccharomyces cerevisiae, Applied Microbiology and Biotechnology, 2020-01, 通讯作者（4）The biological mechanisms of butanol tolerance and the application of solvent-tolerant bacteria for environmental protection, Journal of Chemical Technology & Biotechnology, 2019-12, 通讯作者（5）谷氨酸棒状杆菌高效发酵谷氨酸的关键分子机理研究进展, Research Progress on Key Molecular Mechanism of High Yield Glutamic Acid Fermentation by Corynebacterium glutamicum, 食品工业科技, 2019-05, 通讯作者（6）“Saddle-Shaped” Dose-Survival Effect, Is It a General and Valuable Phenomenon in Microbes in Response to Heavy Ion Beam Irradiation?, Annals of Microbiology, 2019-02, 通讯作者（7）碳离子束辐照诱变选育丁醇耐受菌株, Carbon ion-beam irradiation screening of a butanol-tolerant mutant of Clostridium acetobutylicum, 辐射研究与辐射工艺学报, 2019-02, 通讯作者（8）A genome-wide view of mutations in respiration-deficient mutants of Saccharomyces cerevisiae selected following carbon ion beam irradiation, Applied Microbiology and Biotechnology, 2019, 通讯作者（9）Repair characteristics and time-dependent effects in Saccharomyces cerevisiae cells after X-ray irradiation, World Journal of Microbiology and Biotechnology, 2019, 通讯作者（10）生物丁醇发酵研究进展, Research Progress of Biobutanol Fermentation, 生物技术通报, 2018-08, 通讯作者（11）Cd resistant characterization of mutant strain irradiated by carbon-ion beam, Journal of Hazardous Materials, 2018, 第 5 作者（12）Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpine, BMC Biotechnology, 2018, 第 2 作者（13）Lipidomics Studies on Mitochondrial Damage of Saccharomyces cerevisiae Induced by Heavy Ion Beam Radiation, Chinese Journal of Analytical Chemistry, 2018, 通讯作者（14）A Comet Assay for DNA Damage and Repair After Exposure to Carbon-Ion Beams or X-rays in Saccharomyces Cerevisiae, Dose-Response, 2018, 通讯作者（15）Determining survival fractions of Saccharomyces cerevisiae in response to ionizing radiation in liquid culture, Journal of Radiation Research, 2018, 通讯作者（16）电离辐射对细胞膜的影响综述, Review on ionizing-radiation effect on cell membrane, 辐射研究与辐射工艺学报, 2017-08, 通讯作者（17）X 射线诱变选育嗜酸氧化亚铁硫杆菌及其对难处理金矿浸出的研究, Study on breeding Acidithiobacillus ferrooxidans induced by X-ray irradiation and bioleaching of refractory gold ore, 辐射研究与辐射工艺学报, 2016-10, 第 5 作者（18）重离子束辐照细胞研究的文献计量学分析, A bibliometric analysis on the research focused on cell irradiated by heavy ion beam, 辐射研究与辐射工艺学报, 2016-08, 通讯作者（19）细胞膜对酿酒酵母乙醇耐受性影响的研究进展, Research progress on effect of cell membrane on ethanol tolerance ofSaccharomyces cerevisiae, 中国酿造, 2016-03, 第 2 作者（20）Photosynthetic Effect in Selenastrum capricornutum Progeny after Carbon-Ion Irradiation, PLoS ONE, 2016, 第 3 作者