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个人简介

Qualifications Ph.D., University of Liverpool, 1983 M.Sc., (with Distinction) in Biochemistry, University College London, UK, 1980 B.Sc., (Hons) in Zoology & Biological Chemistry, University of Salford, UK, 1979 Experience Dean, Research & Graduate Studies, XJTLU, (2013 - Now) Professor, Department of Biological Sciences at XJTLU, (2012 - Now) Head, Department of Biological Sciences at XJTLU, (2012 - Now) Acting Head, Department of Environmental Science at XJTLU, (2012 - 2013) Professor and Director, Centre for Proteomic Research, Centre for Biological Sciences, University of Southampton, UK, (2001 - 2012) Reader, School of Biological Sciences, University of Southampton, UK, (2000 - 2001) Senior Lecturer, School of Biological Sciences, University of Southampton, UK, (1995 - 2000) Lecturer, Department of Biochemistry, University of Southampton, UK, (1991 - 1995) Royal Society New Blood Lecturer, Department of Biochemistry, University of Southampton, UK, (1986 - 1991) Royal Society Post-Doctoral Fellow, Department of Medical Biochemistry, University of Geneva Medical School, Switzerland, (1984 - 1986)

研究领域

1. Proteomics – applications and new approaches 2. Molecular microbiology – host-pathogen interactions and survival/stress responses

近期论文

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Erika Parkinson, Pete Boyd, Maja Aleksic, Richard Cubberley, David O'Connor, (2014), Stable isotope labeling method for the investigation of protein haptenation by electrophilic skin sensitizers, Toxicological Sciences, 142 (1), 239-249 ​E Parkinson, P Skipp, M Aleksic, A Garrow, T Gadd, Hughes, M., Clough, G. and O'Connor, C.D., (2014), Proteomic Analysis of the Human Skin Proteome after in vivo treatment with sodium dodecyl sulphate, PLoS ONE, 9 (5), e97772 ​B.M. Jones, M.D. Iglesias-Rodriguez, P.J. Skipp, R.J. Edwards, M.J. Greaves, Young, J.R., Elderfield, H. & O'Connor, C.D., (2013), Responses of the Emiliania huxleyi proteome to ocean acidification, PLoS ONE, 8 (4), e61868 ​C.D. O'Connor, (2012), Beyond the genome, Public Service Review Europe, 24, 340-341 ​C. Gill, E. Parkinson, M.K. Church, P. Skipp, D. Scott, White, A.J., O'Connor, C.D. & Clough, G.F., (2011), A qualitative and quantitative proteomic study of human microdialysate and the cutaneous response to injury, AAPS J., 13, 309-317 ​B.M. Jones, R.J. Edwards, P.J. Skipp, C.D. O'Connor, M.D. Iglesias-Rodriguez, (2011), Shotgun proteomic analysis of Emiliania huxleyi, a marine phytoplankton species of major biogeochemical importance, Marine Biotech., 13, 496-504 ​J.D. Jones, C.D. O'Connor, (2011), Protein acetylation in prokaryotes, Proteomics, 11, 3012-3022 ​P.J Skipp, C.D. O'Connor, (2011), Shotgun proteomics: future perspective in bioanalysis, Bioanalysis, 3, 2159-2160 ​K. Gulla, K. Gupta, A. Krarup, P. Gal, W. Schwaeble, Sim, R., O'Connor, C.D., & Hajela, K., (2010), Activation of MBL-associated serine proteases (MASPs) leads to generation of a fibrin clot, Immunology, 129, 482-495 ​B.L. Nicholas, P. Skipp, S. Barton, D. Singh, D. Bagmane, Mould, R., Angco, G., Ward, J., Guha-Niyogi, B., Wilson, S., Howarth, P., Davies, D.E., Rennard, S., O'Connor, C.D., & Djukanović, R., (2010), Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease, Am. J. Respir. Crit. Care Med., 181, 1049-1060 ​I. Mary, A. Oliver, P. Skipp, R. Holland, J. Topping, (2010), Metaproteomic and metagenomic analyses of defined oceanic microbial populations using microwave cell fixation and flow cytometric sorting, FEMS Microbiol. Ecology, 74, 10-18 ​R.A. McDonald, P. Skipp, J. Bennell, C. Potts, L. Thomas, & O'Connor, C.D., (2009), Mining whole-sample mass spectrometry proteomics data for biomarkers, Expert Systems with Applications, 36, 5333-5340 ​J.N. Williams, P.J. Skipp, C.D. O'Connor, M. Christodoulides, J.E. Heckels, (2009), Immunoproteomic analysis of the development of natural immunity in subjects colonized by Neisseria meningitidis reveals potential vaccine candidates, Infect. Immun., 77, 5080-5089 ​N.R. Thomson, M.T.G. Holden, C. Carder, N. Lennard, S.J. Lockey, Marsh, P., Skipp, P., O'Connor, C.D., Goodhead, I., Norbertzcak, H., Harris, B., Ormond, D., Rance, R., Quail, M.A., Parkhill, J., Stephens, R.S. & Clarke, I.N., (2008), Chlamydia trachomatis: genome sequence analysis of Lymphogranuloma Venereum isolates, Genome Res., 18, 161-171 ​J.N. Williams, P.J. Skipp, H.E. Humphries, M. Christodoulides, C.D. O'Connor, & Heckels, J.E., (2007), Proteomic Analysis of Outer Membranes and Vesicles from Wild-Type Serogroup B Neisseria meningitidis and a Lipopolysaccharide-Deficient Mutant, Infect. Immun., 75, 1364-1372 ​T.E. Vaughan, P.J. Skipp, C.D. O'Connor, M.J. Hudson, R. Vipond, Elmore, M.J. & Gorringe, A.R., (2006), Proteomic analysis of Neisseria lactamica and Neisseria meningitidis outer membrane vesicle vaccine antigens, Vaccine, 24, 5277-5293 ​B. Nicholas, P. Skipp, R. Mould, S. Rennard, D. Davies, O'Connor, C.D. & Djukanovic, R., (2006), Shotgun proteomic analysis of human-induced sputum, Proteomics, 6, 4390-4401 ​P. Skipp, J. Robinson, C.D. O'Connor, I.N. Clarke, (2005), Shotgun proteomic analysis of Chlamydia trachomatis, Proteomics, 5, 1558-1573 ​R.M. Owens, J.G. Pritchard, P. Skipp, M. Hodey, S.R. Connell, Nierhaus, K.H. & O'Connor, C.D., (2004), A dedicated translation factor controls the synthesis of the global regulator Fis, EMBO J., 23, 3375-3385 ​A. Best, R.M. La Ragione, W.A. Cooley, C.D. O'Connor, P. Velge, & Woodward, M.J., (2003), Interaction with avian (Div-1) cells and colonisation of specific pathogen free (SPF) chicks by shiga-toxin negative Escherichia coli O157:H7 (NCTC 12900), Vet. Microbiol., 93, 207-222

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