杨义力 - 中国医学科学院苏州系统医学研究所 -

个人简介

2015-至今苏州系统医学研究所研究员 1998-2014 美国国立卫生研究院国家癌症研究所研究员 1995-1997 美国国立卫生研究院国家癌症研究所高级研究助理 1990-1995 美国国立卫生研究院国家癌症研究所访问学者 1989-1990 美国约翰霍普金斯大学公共卫生学院博士后 1983-1986 第二军医大学病理生理学硕士 1978-1983 第二军医大学医学系本科

研究领域

(1) 发现结直肠癌的基因组突变及基因表达谱改变，并从中找出特征性变化和检测方法，为结直肠癌的个体化预防、诊断、治疗提供依据 (2) 探索泛素化系统，尤其是去泛素化酶在结直肠癌发生、发展中的作用，并通过分子对接、高通量筛选等方法发现小分子抑制剂和可能的新型抗肿瘤药物 (3) 开展相关免疫机制和免疫治疗的研究，着重于肿瘤浸润淋巴细胞的特性和功能，肿瘤细胞突变相关抗原的发现和鉴别，以及T细胞介导的免疫治疗

近期论文

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