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个人简介

2000年 南开大学物理学院本科 2005年 南开大学物理学院生物物理系硕士 2008年 中科院生物物理所博士 2008-2010年 中科院生物物理所助理研究员 2010-2015年 中科院生物物理所副研究员 2014-2015年 美国加州大学洛杉矶分校(UCLA)访问学者 2016年-至今 苏州系统医学研究所研究员

研究领域

研究领域为传染病的计算与系统生物学。

近期论文

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1. Ding X, Luo J Quan L, Wu A†, Jiang T†. Evolutionary genotypes of influenza A (H7N9) viruses over five epidemic waves in China. Infection, Genetics and Evolution 2017, 55, 10.1016/j.meegid.2017.09.027. 2. Weiss DI, Dang AT, Montoya D, Wu A, Gilliet M, Pellegrini M, Modlin RL. Innate activation of Th17 cells triggers IL-26 release. Journal of Immunology 2017, 198, 61.4. 3. Li T, Yao H, Liu D, Ren H, Hu Y, Kargbo D, Teng Y, Deng Y, Lu H, Liu X, Liu K, Fang L, Ning N, Wang G, Dafae F, Kamar A, Wu A, Jiang T, Li Z, Huang J, Sun Y, Qian J, Kargbo B, Jiang J, Wang H, Cao W. Mapping the clinical outcomes and genetic evolution of Ebola virus in Sierra Leone. JCI insight 2017, 2(14):e88333. 4. Peng Y, Li X, Zhou H, Wu A, Dong L, Zhang Y, Gao R, Bo H, Yang L, Wang D, Lin X, Jin M, Shu Y and Jiang T. Continual antigenic diversification in China leads to global antigenic complexity of avian influenza H5N1 viruses. Scientific Reports 2017, 7:43566, doi: 10.1038/srep43566. 5. Zou Y, Wu Z, Deng L, Wu A, Wu F, Li K, Jiang T, Peng Y. cooccurNet: an R package for co-occurrence network construction and analysis. Bioinformatics 2017, btx062. doi: 10.1093/bioinformatics/btx062. 6. Chen Z, Huang A, Sun J, Jiang T, Qin F.X.F†, Wu A†. Inference of immune cell composition on the expression profiles of mouse tissue. Scientific Reports 2017, 7: 40508, doi: 10.1038/srep40508. 7. Xu X*, Wu A*, Zhang X, Su M, Jiang T, Yuan Z. MetaDP: a comprehensive web server for disease prediction of 16S rRNA metagenomic datasets. Biophys Rep 2017. Doi: 10.1007/s41048-016-0033-4. 8. Dai W*, Wu A*, Ma L, Li Y, Jiang T, Li Y. A novel index of protein-protein interface propensity improves interface residue recognition. BMC Systems Biology 2016, 10(Suppl 4):112. 9. Wang Y, Qu J, Ba Q, Dong J, Zhang L, Zhang H, Wu A, Qang D, Xia Z, Peng D, Shu Y, Cao B, Jiang T. Detection and typing of human-infecting influenza viruses in China by using a multiplex DNA biochip assay. J Virol Methods 2016, 234: 178-185. 10. Peng Y, Yang L, Li H, Zou Y, Deng L, Wu A, Du X, Wang D, Shu Y, Jiang T. PREDAC-H3: a user-friendly platform for antigenic surveillance of human influenza A(H3N2) virus based on hemagglutinin sequences. Bioinformatics 2016, 32(16): 2526-2527. 11. Wang L, Valderramos S, Wu A, Ouyang S, Li C, Brasil P, Bonaldo M, Coates T, Nielsen-Saines K, Jiang T, Aliyari R, Cheng G. From mosquitos to humans: Genetic evolution of Zika virus. Cell Host & Microbe 2016, 19(5): 561-565. 12. Wang L*, Wu A*, Wang E. Y*, Quanquin N, Li C, Wang J, Chen H, Liu S, Liu P, Liu Y, Qin X, Jiang T, Cheng G. Functional genomics reveals linkers critical for influenza polymerase. J Virol 2016, 90(6): 2938-2947. 13. Liu W, Wu A, Pellegrini M, Wang X. Integrative analysis of human protein, function and disease networks. Scientific Reports 2015, DOI: 10.1038/srep14344. 14. Liu M, Zhao X, Hua S, Du X, Peng Y, Li X, Lan Y, Wang D, Wu A†, Shu Y† & Jiang T†. Antigenic patterns and evolution of the human influenza A (H1N1) virus. Scientific Reports 2015, 5:14171. 15. Hua S, Li X, Liu M, Cheng Y, Peng Y, Huang W, Tan M, Wei H, Guo J, Wang D, Wu A†, Shu Y† & Jiang T†. Antigenic variation of human influenza A (H3N2) viruses during the 2014-15 winter season. Sci China Life Sci 2015. 16. Liu M, Song T, Hua S, Wu A† & Jiang T†. Computational analysis of antigenic epitopes of avian influenza A (H7N9) viruses. Sci China Life Sci 2015, DOI: 10.1007/s11427-015-4886-4. 17. Deng L, Liu M, Hua S, Peng Y, Wu A, Qin F. X, Cheng G, Jiang T. Network of co-mutations in Ebola virus genome predicts the disease lethality. Cell Research 2015, 25: 753-756. 18. Ma F, Li B, Liu S, Iyer S. S, Yu Y, Wu A, Cheng G. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS. Journal of Immunology 2015, 194(4): 1545-54. 19. Ma M, Yang X, Qian Y, Zhao S, Hua S, Wang T, Chen S, Ma G, Sang X, Liu L, Wu A, Jiang T, Gao Y, Gray G, Zhao T, Ling X, Wang J, Lu B, Qian J, Cao W. Characterization of a novel reassortant influenza A virus (H2N2) from a domestic duck in eastern China. Scientific Reports 4, 2014, doi:10.1038/srep07588. 20. Li H, Peng Y, Zou Y, Huang Z, Wu A, Li K, Jiang T. PREDAC-H5: A user-friendly tool for the automated surveillance of antigenic variants for the HPAI H5N1 virus. Infection, genetics and evolution 2014, 28: 62-63.

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