马瑜婷 - 中国医学科学院苏州系统医学研究所 -

个人简介

2008-2011年法国巴黎第十一大学，博士（免疫学） 2011-2013年法国国家健康与医学研究院，博士后 2013-2015年法国巴黎第五大学，博士后 2015-至今苏州系统医学研究所，研究员 2018-至今苏州系统医学研究所，免疫功能分析与检测平台主任

研究领域

1.细胞应激（自噬、凋亡、程序性坏死、焦亡、内质网应激等）重塑肿瘤免疫微环境、调控抗肿瘤免疫应答的机制 2.精神应激触发的神经内分泌-代谢-免疫-寄居微生物对话网络对肿瘤微环境的组成、微观特征、功能演变的影响及其动态调控规律，探索其对抗肿瘤免疫应答的调控机制

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Ma Y†, Kroemer G†. The cancer-immune dialogue in the context of mental stress. Nat Rev Immunol. 2020 (submitted) Yang H*, Xia L*, Chen J*, Zhang S, Martin V, Li Q, Lin S, Chen J, Calmette J, Lu M, Fu L, Yang J, Pan Z, Yu K, He J, Morand E, Schlecht-Louf G, Krzysiek R, Zitvogel L, Kang B, Zhang Z, Leader A, Zhou P, Lanfumey L, Shi M, Kroemer G, Ma Y†. Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity. Nat Med. 2019 Sep;25(9):1428-1441. Ma Y†, Yang H, Kroemer G†. Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies. Oncoimmunology. 2019 Oct 11;9(1):1673635. Zitvogel L†, Ma Y, Raoult D, Kroemer G, Gajewski TF†. The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies. Science. 2018 Mar 23;359(6382):1366-1370 Ma Y†, Pitt JM, Li Q, Yang H. (2017) The renaissance of anti-neoplastic immunity from tumor cell demise. Immunol Rev. 2017 Nov;280(1):194-206. Stoll G, Ma Y, Yang H, Kepp O, Zitvogel L, Kroemer G†. Pro-necrotic molecules impact local immunosurveillance in human breast cancer. Oncoimmunology 2017 Apr 17;6(4):e1299302. Vechelli E., Ma Y, Baracco E.E, Zitvogel L, Kroemer G. Yet another pattern recognition receptor involved in the chemotherapy-induced anticancer immune response: formyl peptide receptor-1. Oncoimmunology 2016; 30;5(5):e1118600. Ma Y†, Yang H, Pitt J.M., Kroemer G, Zitvogel L†. Therapy-induced microenvironmental changes in cancer. J Mol Med (Berl), 2016; 94(5):497-508. Yang H*, Ma Y*†, Chen G, Zhou H, Yamazaki T, Klein C, Vacchelli E, Pietrocola F, Souquere S, Sauvat A, Zitvogel L, Kepp O, Kroemer G†. Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy. Oncoimmunology 2016; 10;5(6):e1149673. Yang H, Yamazaki T, Pietrocola F, Zhou H, Zitvogel L, Ma Y†, Kroemer G†. Improvement of immunogenic chemotherapy by STAT3 inhibition. Oncoimmunology 2015; Sep. DOI: 10.1080/2162402X.2015.1078061. Yang H, Yamazaki T, Pietrocola F, Zhou H, Zitvogel L, Ma Y†, Kroemer G†. STAT3 Inhibition Enhances the Therapeutic Efficacy of Immunogenic Chemotherapy by Stimulating Type 1 Interferon Production by Cancer Cells. Cancer Res 2015; Sep 15;75(18):3812-22. Vacchelli E*, Ma Y*, Baracco EE, Sistigu A, Enot DP, Pietrocola F, Yang H, et al. Chemotherapy-induced anti-tumor immunity requires formyl peptide receptor 1. Science 2015 Oct 29. pii: aad0779. Ma Y, Mattarollo SR, Adjemian S, Yang H, Aymeric L, Hannani D, et al. CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. Cancer Res 2014; 74:436-45. (Cover story) Ma Y, Adjemian S, Galluzzi L, Zitvogel L, Kroemer G. Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy. Oncoimmunology 2014; 3:e27663. Ma Y*, Adjemian S*, Mattarollo SR, Yamazaki T, Aymeric L, Yang H, et al. Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells. Immunity 2013; 38:729-41. Ma Y, Galluzzi L, Zitvogel L, Kroemer G. Autophagy and cellular immune responses. Immunity 2013; 39:211-27. Ma Y, Yamazaki T, Yang H, Kepp O, Galluzzi L, Zitvogel L, et al. Tumor necrosis factor is dispensable for the success of immunogenic anticancer chemotherapy. Oncoimmunology 2013; 2:e24786. Ma Y, Adjemian S, Yang H, Catani JP, Hannani D, Martins I, et al. ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy. Oncoimmunology 2013; 2:e24568. Wang Y, Martins I, Ma Y, Kepp O, Galluzzi L, Kroemer G. Autophagy-dependent ATP release from dying cells via lysosomal exocytosis. Autophagy 2013; 9:1624-5. Hannani D, Ma Y, Yamazaki T, Dechanet-Merville J, Kroemer G, Zitvogel L. Harnessing gammadelta T cells in anticancer immunotherapy. Trends Immunol 2012; 33:199-206.

学术兼职

中国抗癌协会肿瘤代谢专业委员会常务委员中国抗癌协会肿瘤微环境专业委员会委员手术与细胞治疗学术委员会常务委员中国免疫学会基础免疫分会委员中国免疫学会青年工作委员会委员中国细胞生物学会永久会员法国免疫学会会员欧洲肿瘤免疫学院会员 eLife审稿编辑 Current Research Immunology编辑