李晔 - 重庆大学 - 医学高等研究院（医学院）

个人简介

学习经历 1.2002/8-2008/5，Duke University，Neurobiology，博士，导师：David Fitzpatrick 2.1997/9-2002/7，北京大学医学部，基础医学，学士，导师：韩济生院士工作经历 1.2019/7-⾄今，重庆大学，医学院，教授，博士生导师 2.2015/5-2019/6，浙江大学，医学院/管理学院，PI研究员，博⼠⽣导师 3.2010/8-2015/4，美国加州伯克利大学，Research Associate（助理研究员） 4.2008/5-2010/7，美国杜克大学（Duke University），神经生物学，Postdoc（博⼠后）教学课程：基础医学、临床医学、神经生物学招生资格：硕士、博士研究生导师，博士后合作导师著作（1）Van Hooser DS, Johnson EN, Li Y, Culp J. Arani R, Kasliwal R and Flavahan K (2014)Practical methods for in vivo cortical physiology with 2-photon microscopy and bulkloading of fluorescent calcium indicator dyes.Neuronal Tracing Methods: Tracing Neurons and their connections. 92: 117-41 （2）Li Y, Van Hooser SD, White LE and Fitzpatrick D (2010) Cortex under construction:visual experience and the development of direction selectivity.Cerebral Plasticity:New Perspectives. The MIT Press: 2010 3.会议报告（1）Li A, Wu S, Zhang X and Li Y (2018) Emergence of balanced orientation selectivity in the primary visual cortex (# 501). Cosyne, Denver, Colorado, USA (2)Li Y (2016), Development origin of the function and circuits organization in the mouse visual cortex, Francis Crick Symposium: Advances in Neuroscience. CSHA, Suzhou,China (3)Li Y, Lu H, Cheng PL, Ge S, Xu H, Shi SH and Dan Y (2012) Clonally related visual cortical neurons show similar stimulus feature selectivity. Soc.Neurosci. Abstr. 567.11 (4)Corlew RJ*, Li Y*,White LE and Fitzpatrick D (2010) Rapid emergence of direction selective responses in ferret visual cortex without training geniculocortical synapses. Soc.Neurosci. Abstr. (5)Christensson M*, Li Y*, Van Hooser SD, White LE and Fitzpatick D (2009) Effect of dark rearing on the development of direction preference in developing visual cortex. Soc.Neurosci. Abstr. (6)Van Hooser SD*, Li Y*, Christensson M, White LE and Fitzpatick D (2008) Emergence and refinement of direction preference in developing visual cortex. Soc.Neurosci.Abstr. (7)Van Hooser SD*, Li Y*, Mazurek M, White LE and Fitzpatick D (2007) Imaging experience-dependent development of cortical direction selectivity with single-cell. Soc.Neurosci. Abstr. 346.8 (8)Li Y, White LE and Fitzpatrick D (2006) Cortical activation mediates the experience dependent emergence of direction selectivity. Soc. Neurosci. Abstr. 916.6 (9)Li Y, Fitzpatrick D and White LE (2005) Normal Sensory Experience is necessary for the development of direction selectivity in ferret visual cortex.S oc. Neurosci. Abstr.978.6 4.专利发明专利：A Mirror-Neuron based VR Rehabilitation System Li Y et al 201710725508.1 审核中实⽤新型专利：⼀种基于镜像神经元的虚拟现实（VR）康复系统Li Y et al 201721055930.2 批准 5.项目 1. 国家高层次引进人才青年项目,2015 2. 国家自然科学基⾦（重⼤项⽬）负责人，2016

研究领域

研究方向：主要开展⼤脑⽪层微尺度信息传⼊活动图的绘制、从事双光⼦显微镜等先进脑成像技术与脑神经系统精准可视化调控技术的研发，精细阐明脑电的神经⽣物学基础。近年来⾃主研发基于双光⼦技术的微尺度全脑成像和调控技术，实现设备的⼩型化，最终达到同步“读脑”-“写脑”的精准调控；在“读脑”的基础上，发展全新的、颠覆性的深穿透脑磁⼲预、多通道多靶点神经电刺激、深穿透光学调控、超声及虚拟现实/混合现实等⾼端交叉技术，实现精准“控脑”。

近期论文

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文章 (1) Wang D, Wang A, Wu F, Qiu X Li Y* et al (2017) Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. Sci Rep. 7: 40295 (2) Li Ye ，Lu Hui ，Cheng Pei-lin，Ge Shaoyu，Xu Huatai，Shi Song-Hai，Dan Yang，Clonally related visual cortical neurons show similar stimulus feature selectivity. Nature，2012，486（7401）：118-121。 (3) Li Ye* ，Van Hooser, Stephen D*，Christensson, Maria，Smith, Gordon，White,Leonard E，Fitzpatrick, David，Initial neighborhood biases and the quality of motion stimulation jointly influence the rapid emergence of direction preference in visual cortex. J Neurosci，2012，32（21）：7258-7266。 (4) Li Ye ，Van Hooser, Stephen D ，Mazurek, Mark，White, Leonard E，Fitzpatrick,David，Experience with moving visual stimuli drives the early development of cortical direction selectivity. Nature，2008，456（7224）：952-956。 (5) Li Ye，Fitzpatrick, David，White, Leonard E，The development of direction selectivity in ferret visual cortex requires early visual experience. Nat Neurosci，2006，9（5）：676-681。