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1. Lim DS, Kim ST, Xu B, Maser RS, Lin J, Petrini JH, Kastan MB. Atm phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature 404: 613-617; 2000. Faculty of 1000 Prime recommended
2. Xu B, Kim ST and Kastan MB. Involvement of Brca1 in S-phase and G2-phase checkpoint after ionizing irradiation Molecular and Cellular Biology 21:3445-3450; 2001. Faculty of 1000 Prime recommended
3. Kim ST, Xu B (co-first author) and Kastan MB. Involvement of the Cohesin Protein, Smc1, in ATM–Dependent and–Independent Responses to DNA Damage. Genes & Development 16: 560-570, 2002. Faculty of 1000 Prime recommended
4. Xu B, Kim St, Lim DS, Kastan MB. Two Molecularly Distinct G2/M checkpoints Are Induced by Ionizing Irradiation Molecular and Cellular Biology 22 (4): 1049-1059; 2002.
5. Taniguchi T, Garcia-Higuera I, Xu B, Anderson P, Gregory R, Lane W, Kim S, Kastan MB, D’Andrea A. Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways. Cell 109: 459-472, 2002. Faculty of 1000 Prime recommended
6. Xu B, O’Donnell AH, Kim ST, Kastan MB. Phosphorylation of Serine 1387 in Brca1 is specifically required for the Atm-Mediated S-phase Checkpoint after Ionizing Irradiation. Cancer Research. Aug 15; 62(16):4588-91, 2002.
7. Garg, R., Geng, C.-D., Miller, J. L., Callens, S., Tang, X., Appel, B., Xu, B.* Molecular Cloning and Characterization of the Catalytic Domain of Zebrafish Homologue of the Ataxia-Telangiectasia Mutated Gene. Molecular Cancer Research 2: 348-353, 2004. Also featured the cover page of the issue.
8. Garg, R., Callens, S., Lim, D.-S., Canman, C. E., Kastan, M. B., Xu, B*. Chromatin Association of Rad17 Is Required for an Ataxia Telangiectasia and Rad-Related Kinase-Mediated S-Phase Checkpoint in Response to Low-Dose Ultraviolet Radiation. Molecular Cancer Research 2: 362-369, 2004.
9. Xu B*, Kastan MB. Analyzing cell cycle checkpoints after ionizing radiation. Methods Mol Biol.; 281: 283-92, 2004
10. Arlt, M. F., Xu, B., Durkin, S. G., Casper, A. M., Kastan, M. B., Glover, T. W.BRCA1 Is Required for Common-Fragile-Site Stability via Its G2/M Checkpoint Function. Molecular and Cellular Biology 24: 6701-6709, 2004.
11. Wakeman TP, Kim WJ, Callens S, Chiu A, Brown KD, Xu B*. The ATM-SMC1 Pathway is Essential for Activation of the Chromium [VI]-induced S-Phase Checkpoint. Mutation Research, 554(1-2):241-51, 2004.
12. Timothy Wakeman, Dorota Wyczechowska, and Bo Xu*. Involvement of the p38 MAP kinase in chromium-induced growth arrest and apoptosis. Mol Cell Biochem. 2005 Nov; 279(1-2):69-73
13. Timothy Wakeman, Renu Garg, and Bo Xu*, ATR regulates Cr-induced S-phase checkpoint through dissociation from Rad17. Mutation Research 2006 Nov 7; 610(1-2):14-20.
14. Mickael Cariveau, Jessie Tang, Xiaoli Cui, and Bo Xu*. Conserved NBS1 C-terminal small peptides can inhibit the ATM-mediated DNA damage response and enhance radiation sensitivity. Molecular Pharmacology, AUG 2007, 72(2): 320-326.
15. Mickael J. Cariveau, Murray Stackhouse, Xiao-li Cui, Kamal Tiwari, William Waud, John A. Secrist III, Bo Xu*. Clofarabine acts synergistically with ionizing radiation in vitro and in vivo by interfering with the DNA damage response, International Journal of Radiation Oncology, Biology, Physics, 2008, 70: 213-220
16. Xi Tang, Zhou-guang Hui, Xiao-li Cui, Renu Garg, Michael B. Kastan, and Bo Xu*. A novel ATM-dependent pathway regulates Protein Phosphatase 1 and histone H3 phosphorylation in response to DNA damage. Molecular Cellular Biology April 4, 2008, 2559-2566, Faculty of 1000 Prime recommended
17. Zhang C, Kang C, Wang P, Cao Y, Lv Z, Yu S, Wang G, Zhang A, Jia Z, Han L, Yang C, Ishiyama H, Teh BS, Xu B*, Pu P. (co-corresponding authors). MicroRNA-221/-222 regulate radiation sensitivity by targeting the PTEN pathway, International Journal Of Radiation Oncology, Biology and Physics, 2011 May 1;80(1):240-8.
18. Chunying Yang, ,Xi Tang, Xiaojing Guo, Yohei Niikura, Katsumi Kitagawa,Kemi Cui, Stephen T.C. Wong, Li Fu, and Bo Xu*. Aurora-B Mediated ATM Serine 1403 Phosphorylation Is Required For Mitotic ATM Activation and theSpindle Checkpoint. Molecular Cell. 44, 597-608 November 18, 2011. (appeared as issue highlights, article previewed, top-read, and Faculty of 1000 Prime recommended)
19. Chunying Yang, Haibo Wang, Yiran Xu, Kathryn Brinkman, Stephen Wong and Bo Xu*. The kinetochore protein Bub1 is required for DNA damage responses. DNA Repair 2012 Feb 1; 11(2):185-91. Epub 2011 Nov 9.
20. Mianen Sun, Xiaojing Guo, Chunying Yang, Kathryn Brinkman, David Engler, Binhua Zhou, Li Fu, Bo Xu*. Activation of the ATM-Snail pathway promotes breast cancer metastasis, Journal Of Molecular Cell Biology, 2012 Oct;4(5):304-15
21. Xiaonan Sun, Chunying Yang, Hai Liu, Wang Qi, Shi-Xiu Wu, Xia Li, Tian Xie, Kathryn, L. Brinkman, Bin S. Teh, E. Brain Butler, Bo Xu* and Shu Zheng*. Identification and Characterization of a Small Inhibitory Peptide that can Target DNA-PKcs Autophosphorylation and Increase Tumor Radiosensitivity. International Journal of Radiation Oncology, Biology and Physics. 2012 May 15, 84 (5), 1212-1219
22. Chun-ying Yang , Mike Lee, Jessie Tang, Xiaoli Cui, Paula Allen, Françoise Bontemps, William B. Parker, and Bo Xu*. Deoxycytidine kinase regulates the G2M checkpoint through interaction with Cyclin-Dependent Kinase 1 in response to DNA damage. Nucleic Acids Research, 2012 July 31. 40 (19), 9621-9632
23. Boohaker, R.; Cui, X.; Stackhouse, M.; Xu, B. ATM-mediated Snail Serine 100 Phosphorylation Regulates Cellular Radiosensitivity. Radiotherapy and Oncology. 7-25-2013.
24. Xiaojing Guo , Chunying Yang , Xiaolong Qian , Ting Lei , Yaqing Li , Haifa Shen , Li Fu and Bo Xu*. Estrogen Receptor Alpha regulates ATM expression through miRNAs in breast cancer, Clinical Cancer Research, Published Online First July 15, 2013; doi:10.1158/1078-0432.CCR-12-3700
25. Boohaker, R.; Xu B*. The Versatile functions of the ATM Kinase. Biomedical Journal 2014 Jan-Feb;37(1):3-9.
26. Zhang, D.; Wang, H.; Sun, M.; Yang, J.; Zhang, W.; Han, S.; Xu, B*. Speckle-type POZ protein, SPOP, is involved in the DNA damage response. Carcinogenesis. 2014 Aug;35(8):1691-7
27. Chunying Yang, Xiaojing Guo, Haibo Wang, David Engler, Wei Zhang, and Bo Xu*. Mad1 Serine 214 phosphorylation is critical for its role in mitotic spindle checkpoint activation. Carcinogenesis. 2014, Sep; 35(9):2007-13.
28. 54.Rebecca J Boohaker, Bo Xu, The Role of MicroRNAs in Modulating Tissue Response to Radiation, in Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment, Springer Nature press 2016
29. Nathaniel H. Boyd, M.S.1*, Kiera Walker, M.A.1*, Joshua Fried, B.S.2, James R. Hackney, M.D.3, Paul C. McDonald, Ph.D.4, Gloria A. Benavides, Ph.D.5, Raffaella Spina, Ph.D.6, Alessandra Audia, Ph.D.7, Sarah E. Scott1, Catherine J. Libby, B.S.1, Anh Nhat Tran, B.S.1, Mark O. Bevensee, Ph.D.1, Corinne Griguer, Ph.D.8, Susan Nozell, Ph.D.9, G. Yancey Gillespie, Ph.D.8, Burt Nabors, M.D.10, Krishna P. Bhat, Ph.D.7, Eli E. Bar, Ph.D.6, Victor Darley-Usmar, Ph.D.5, Bo Xu, M.D., Ph.D.2, Emily Gordon, Ph.D. 11, Sara J. Cooper,Ph.D.11, Shoukat Dedhar, Ph.D.4, Anita B. Hjelmeland, Ph.D.1 Addition of Carbonic Anhydrase 9 Inhibitor SLC-0111 to Temozolomide Treatment Delays Glioblastoma Growth in Vivo, Journal of Clinical Investigation (JCI) Insights, 2017;2(24):e92928. https://doi.org/10.1172/jci.insight.92928.
30. Wei X, Fried J, Li Y, Hu L, Gao M, Zhang S, Xu B. Functional roles of Speckle-Type Poz (SPOP) Protein in Genomic stability. J Cancer. 2018 Sep 7;9(18):3257-3262. doi: 10.7150/jca.25930.
31. Boohaker RJ, Sambandam V, Segura I, Miller J, Suto M, Xu B. Rational design and development of a peptide inhibitor for the PD-1/PD-L1 interaction. Cancer Lett. 2018 Oct 10;434:11-21. doi: 10.1016/j.canlet.2018.04.031. Epub 2018 Jun 18.
32. Wei X, Cai S, Boohaker RJ, Fried J, Li Y, Hu L, Pan Y, Cheng R, Zhang S, Tian Y, Gao M, Xu B.，KAT5 promotes invasion and metastasis through C-MYC stabilization in ATC. Endocrine Related Cancer. 2019 Jan 1;26(1):141-151. doi: 10.1530/ERC-18-0193.
33. Ying Y, Wang Y, Huang X, Sun Y, Zhang J, Li M, Zeng J, Wang M, Xiao W, Zhong L, Xu B, Li L, Tao Q, Wang X, Shu XS Oncogenic HOXB8 is driven by MYC-regulated super enhancer and potentiates colorectal cancer invasiveness via BACH1.Oncogene. 2019 Oct 7. doi: 10.1038/s41388-019-1013-1
34. Zhao Z, Li L, Du P, Ma L, Zhang W, Zheng L, Lan B, Zhang B, Ma F, Xu B, Zhan Q, Song Y. Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer. Theranostics. 2019 Feb 20;9(5):1401-1416. doi: 10.7150/thno.30701.
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