当前位置: X-MOL首页全球导师 国内导师 › 张丽华

个人简介

1995年毕业于吉林大学化学系。同年进入中国科学院大连化学物理研究所攻读博士学位,师从张玉奎院士;主要开展毛细管电色谱基础理论和新技术的研究。1999年赴德国国家环境与健康研究中心博士联合培养,师从A. Kettrup教授;从事毛细管电泳和质谱联用于金属蛋白的分析。2000年获得理学博士学位。2001年-2003年3月,在日本德岛大学马场嘉信教授研究室做博士后;从事基因组快速分析的研究工作。2003年4月回中国科学院大连化学物理研究所工作;2005年获得择优支持;2005年晋升为研究员,课题组长。获得国家自然科学二等奖、辽宁省自然科学一等奖、中国分析测试协会CAIA一等奖和中国化学会青年化学奖等奖项。2012年入选科技部“中青年科技创新领军人才”(万人计划)。2017年获国家杰出青年基金项目资助。已发表SCI文章200多篇;申请发明专利50多项,授权20余项;参与了7本中英文著作的编写。现任Analytical Bioanalytical Chemistry,Science China-Chemistry, Proteomics 和《色谱》编委。

研究领域

样品预处理和分离新材料;多维多模式液相分离新技术;高灵敏度检测和鉴定新方法;集成化高通量分析新平台;蛋白质组定性定量分析新方法

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Jing Chen#, Qun Zhao#*, Hang Gao, Lili Zhao, Huiying Chu, Yichu Shan, Zhen Liang, Yukui Zhang, Lihua Zhang*, A Glycosidic-Bond-Based Mass-Spectrometry-Cleavable Cross-linker Enables In Vivo Cross-linking for Protein Complex Analysis, Angewandte Chemie International Edition, 2023, 62: e202212860. Beirong Zhang#, Zhou Gong#*, Lili Zhao, Yuxin An, Hang Gao, Jing Chen, Zhen Liang, Maili Liu, Yukui Zhang, Qun Zhao,* and Lihua Zhang*, Decoding Protein Dynamics in Cells Using Chemical Cross-Linking and Hierarchical Analysis. Angewandte Chemie International Edition, 2023, e202301345. Yuwan Chen, Wen Zhou, Yufei Xia, Weijie Zhang, Qun Zhao, Xinwei Li, Hang Gao, Zhen Liang, Guanghui Ma, Kaiguang Yang*, Lihua Zhang*, Yukui Zhang, Targeted cross-linker delivery for the in situ mapping of protein conformations and interactions in mitochondria, Nature Communications, 2023, 14: 3882. Baofu Ma#, Kun Zhang#, Zhen Sun, Hui Pan, Kaiguang Yang, Bo Jiang*, Baofeng Zhao*, Zhen Liang, Yukui Zhang, Lihua Zhang*, Pushpin-like Nanozyme for Plasmon-Enhanced Tumor Targeted Therapy, Acta Biomaterialia, 2023, 158: 673-685. Baofu Ma, Jianyu Han, Qun Zhao, Bo Jiang, Zhixin Zhang*, Baofeng Zhao*, Zhen Liang, Yukui Zhang, Lihua Zhang*, Platinum Engineering on Nanoceria Surface toward High Catalytic Activity for Inducing Tumor Cell Apoptosis and Inhibiting Migration, Acs Sustainable Chemistry & Engineering, 2023, 11: 6163-6172. Xinwei Li, Yuwan Chen, Jing Jiang, Wen Zhou, Hang Gao, Qun Zhao, Zhen Liang, Xupeng Cao*, Kaiguang Yang*, Lihua Zhang*, and Yukui Zhang, Crosslinker Nanocarriers Delivery to Chloroplasts for In Vivo Mapping of Photosynthetic Membrane Protein Complexes in Living Chlamydomonas reinhardtii Cells, Analytical Chemistry, 2023, 95: 9555-9563. Beirong Zhang, Hang Gao, Zhou Gong, Lili Zhao, Bowen Zhong, Zhigang Sui, Zhen Liang, Yukui Zhang, Qun Zhao*, and Lihua Zhang*, Improved Cross-Linking Coverage for Protein Complexes Containing Low Levels of Lysine by Using an Enrichable Photo-Cross-Linker, Analytical Chemistry, 2023, 95: 9445-9452. Wen Zhou, Zhigang Sui, Jianhui Liu, Yingyun He, Huiming Yuan, Yue Sun, Zhen Liang, Kaiguang Yang*, Lihua Zhang*, and Yukui Zhang, High-Sensitivity Detection toward SARS-CoV-2 S1 Glycoprotein by Parallel Reaction Monitoring Mass Spectrometry, Analytical Chemistry, 2023, 95: 8752-8757. Yue Sun, Yu Liang*, Chao Wang, Baofeng Zhao, Zhen Liang, Xiaodan Zhang, Yukui Zhang, Lihua Zhang*, Enhancing Top-Down Characterization of Membrane Proteoforms with C8-Functional Amine-Bridged Hybrid Monoliths, Analytical Chemistry, 2023, 95: 6846-6853. Li Guan*, Yanyan Zhou, Xiao Li, Yongbao Mao, Anyang Li, Yile Fu, Wen Liu, Sheying Dong, Zhen Liang, Yukui Zhang, Qun Zhao*, and Lihua Zhang*, ON-OFF Fluorescent Cyanine Dye Based on a Benzothiophenyl Rotor Enables Selective Illumination of G-Quadruplexes in Mitochondria, Analytical Chemistry, 2023, 95: 9288-9296. Bowen Zhong, Yuxin An, Hang Gao, Lili Zhao, Xiao Li, Zhen Liang, Yukui Zhang, Qun Zhao*, Lihua Zhang*, In vivo cross-linking-based affinity purification and mass spectrometry for targeting intracellular protein-protein interactions, Analytica Chimica Acta, 2023, 1265: 341273. Mingwei Sun#, Qing Zhang#, Baofeng Zhao, Qiuling Huang, Wenfeng Wu, Peiyang Fan, Lihua Zhang*, Xiaofei Zhang*, Antibody-free approach for ubiquitination profiling by selectively clicking the ubiquitination sites, Analytica Chimica Acta, 2023, 1246: 340877. Weijie Zhang, Yichu Shan, Lili Zhao, Zhen Liang, Chao Liu*, Lihua Zhang*, Yukui Zhang, ComMap: a software to perform large-scale structurebased mapping for cross-linking mass spectrometry, Bioinformatics, 2023, 39: btad077. Zuoling Wen, Yuebin Zhang, Beirong Zhang, Yumo Hang, Li Xu, Yangsheng Chen, Qunhui Xie, Qun Zhao, Lihua Zhang, Guohui Li, Bin Zhao, Fei Sun*, Yujia Zhai*, Yun Zhu*, Cryo-EM structure of the cytosolic AhR complex, Structure, 2023, 31: 295-308. Yu Liang, Lihua Zhang*, Yukui Zhang, Chromatographic separation of peptides and proteins for characterization of proteomes, Chemical Communications, 2023, 59: 270-281. Meixi He, Yi Wang, Xiaozhe Zhang, Lihua Zhang, Exploration of the potential neuroprotective compounds targeting GluN1-GluN2B NMDA receptors, Journal of Biomolecular Structure and Dynamics, 2023. Hui Pan, Baofu Ma, He Wang, Xulian, Cui, Kun Zhang, Baofeng Zhao*, Bo Jiang*, Zhen Liang, Lihua Zhang, Yukui Zhang, Efficient Enrichment Method for N-Phosphorylation Peptides in Mouse Brain Tissue, Journal of the American Society for Mass Spectrometry. 2023, 34: 145-148. Yilan Li#, Huiming Yuan*#, Mengchun Cheng, Xudong Zhu, Kaiguang Yang, Weijie Zhang, Zhigang Sui, Chunyu Zhang*, Lihua Zhang*, Yukui Zhang, Solid-phase alkylation: a low-loss and anti-interference sample preparation strategy for low-input proteome profiling, Science Bulletin, 2022, 67: 1628-1631. Fang Liu, Xuan Wang, Jianli Duan, Zhijie Hou, Zhouming Wu, Lingling Liu, Hanqi Lei, Dan Huang, Yifei Ren, Yue Wang, Xinyan Li, Junxiao Zhuo, Zijian Zhang, Bin He, Min Yan, Huiming Yuan, Lihua Zhang, Jinsong Yan, Shijun Wen*, Zifeng Wang*, Quentin Liu*, A Temporal PROTAC Cocktail-Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells, Advanced Science, 2022, 9: 2104823. Huan Feng#, Qun Zhao#, Beirong Zhang, Hang Hu, Meng Liu, Kaifeng Wu, Xiaosong Li, Xin Zhang*, Lihua Zhang*, Yu Liu*, Enabling Photo-Crosslinking and Photo-Sensitizing Properties for Synthetic Fluorescent Protein Chromophores. Angewandte Chemie International Edition, 2022, e202215215. Xiaoyao Song#, Jianhui Liu#, Ningbo Geng, Yichu Shan, Baoqin Zhang, Baofeng Zhao, Yuwen Ni, Zhen Liang, Jiping Chen*, Lihua Zhang*,Yukui Zhang, Multi-omics analysis to reveal disorders of cell metabolism and integrin signaling pathways induced by PM2.5, Journal of Hazardous Materials, 2022, 424, 127573. Shen Chen#, Liping Chen#, Lizhu Ye#, Yue Jiang, Qiong Li, Haiyan Zhang, Rui Zhang, Huiyao Li, Dianke Yu, Rong Zhang, Yujie Niu, Qun Zhao, Jianhui Liu, Gangfeng Ouyang, Michael Aschnerf, Yuxin Zheng, Lihua Zhang, Wen Chen*, Daochuan Li*, PP2A-mTOR-p70S6K/4E-BP1 Axis Regulates M1 Polarization of Pulmonary Macrophages and Promotes Ambient Particulate Matter Induced Mouse Lung Injury, Journal of Hazardous Materials, 2022, 424: 127624. Weijie Zhang#, Pengyun Gong#, Yichu Shan#, Lili Zhao, Hongke Hu, Qiushi Wei, Zhen Liang, Chao Liu*, Lihua Zhang*, Yukui Zhang, SpotLink enables sensitive and precise identification of site nonspecific cross-links at the proteome scale, Briefings in Bioinformatics, 2022, 23, bbac316. Xuemei Hu, Nan Shen, Anqi Liu, Weidong Wang, Lihua Zhang, Zhigang Sui, Qingzhu Tang, Xiangning Du, Ning Yang, Wantao Ying, Biaojie Qin, Zhitong Li, Lin Li, Nan Wang*, Hongli Lin*, Bone Marrow Mesenchymal Stem Cell-derived Exosomal MiR-34c-5p Ameliorates RIF by Inhibiting the Core Fucosylation of Multiple Proteins, Molecular Therapy, 2022, 30: 763-781. Changqing Wu, Chaoliu Dai, Xinyu Li, Mingju Sun, Hongwei Chu, Qiuhui Xuan, Yalei Yin, Chengnan Fang, Fan Yang, Zhonghao Jiang, Qing Lv, Keqing He, Yiying Qu1, Baofeng Zhao, Ke Cai, Shuijun Zhang, Ran Sun, Guowang Xu, Lihua Zhang, Siyu Sun*, Yang Liu*, AKR1C3-dependent lipid droplet formation confers hepatocellular carcinoma cell adaptability to targeted therapy, Theranostics, 2022,12, 7681-7698. He Wang, Zhiting Wang, Hang Gao, Jianhui Liu, Zichun Qiao, Baofeng Zhao, Zhen Liang, Bo Jiang*, Lihua Zhang*, Yukui Zhang, A photo-oxidation driven proximity labeling strategy enables profiling of mitochondrial proteome dynamics in living cells, Chemical Science, 2022, 13: 11943-11950. Hongwei Chu#, Qun Zhao#, Ju Liu, Kaiguang Yang, Yanlei Wang, Jianhui Liu, Kun Zhang, Baofeng Zhao*, Hongyan He*, Yong Zheng, Shijun Zhong, Zhen Liang, Lihua Zhang*, Yukui Zhang, Ionic Liquid-Based Extraction System for In-Depth Analysis of Membrane Protein Complexes, Analytical Chemistry, 2022, 94: 758-767. Yuxin An, Qun Zhao*, Hang Gao, Lili Zhao, Xiao Li, Xiaodan Zhang, Zhen Liang, Lihua Zhang*, Yukui Zhang, Selective Removal of Unhydrolyzed Monolinked Peptides from Enriched Crosslinked Peptides To Improve the Coverage of Protein Complex Analysis, Analytical Chemistry, 2022, 94: 3904-3913. Yu Liang, Chao Wang, Zhen Liang, Lihua Zhang*, Yukui Zhang, C18-Functionalized Amine-Bridged Hybrid Monoliths for Mass Spectrometry-Friendly Peptide Separation and Highly Sensitive Proteomic Analysis, Analytical Chemistry, 2022, 94: 6084-6088. Hongwei Chu#, Qun Zhao*#, Yichu Shan#, Shen Zhang, Zhigang Sui, Xiao Li, Fei Fang, Baofeng Zhao*, Shijun Zhong, Zhen Liang, Lihua Zhang*, Yukui Zhang, All-Ion Monitoring-Directed Low-Abundance Protein QuantificationReveals CALB2 as a Key Promoter in Hepatocellular CarcinomaMetastasis, Analytical Chemistry, 2022, 94: 6102-6111. Chao Wang, Yu Liang*, Baofeng Zhao, Zhen Liang, Lihua Zhang*, Yukui Zhang, Ethane-Bridged Hybrid Monolithic Column with Large Mesopores for Boosting Top-Down Proteomic Analysis, Analytical Chemistry, 2022, 94: 6172-6179. Hang Gao, Lili Zhao, Bowen Zhong, Beirong Zhang, Zhou Gong, Baofeng Zhao, Yi Liu, Qun Zhao*, Lihua Zhang*, Yukui Zhang, In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker, Analytical Chemistry, 2022, 94: 7551-7558. Jianhui Liu#, Yuan Zhou#, Xinhang Hou, Chao Liu, Baofeng Zhao, Yichu Shan, Zhigang Sui, Zhen Liang, Lihua Zhang*, Yukui Zhang, A1 Ions: Peptide-Specific and Intensity-Enhanced Fragment Ions for Accurate and Multiplexed Proteome Quantitation, Analytical Chemistry, 2022, 94: 7637-7646. Chao Wang, Yu Liang*, Xue Yang, Bowen Zhong, Xiaodan Zhang, Baofeng Zhao, Zhen Liang, Lihua Zhang*, Yukui Zhang, Surface-Charged Hybrid Monolithic Column for MS-Compatible Peptide Separation with High Peak Capacity and Its Application in Proteomic Analysis, Analytical Chemistry, 2022, 94: 9525-9529. Yuxin An, Qun Zhao*, Zhou Gong, Lili Zhao, Yi Li, Zhen Liang, Peng Zou, Yukui Zhang, Lihua Zhang*, Suborganelle-Specific Protein Complex Analysis Enabled by in Vivo Cross-Linking Coupled with Proximal Labeling, Analytical Chemistry, 2022, 94: 12051-12059. Hang Gao, Qun Zhao*, Zhou Gong, Bowen Zhong, Jing Chen, Zhigang Sui, Xiao Li, Zhen Liang, Yukui Zhang, Lihua Zhang*, Alkynyl-Enrichable Carboxyl-Selective Crosslinkers to Increase the Crosslinking Coverage for Deciphering Protein Structures, Analytical Chemistry, 2022, 94: 12398-12406. Di Shen#, Wenhan Jin#, Qun Zhao#, Mengdie Wang, Beirong Zhang, Huan Feng, Wang Wan, Yulong Bai, Haochen Lyu, Jialu Sun, Lihua Zhang*, and Yu Liu*, Covalent Solvatochromic Proteome Stress Sensor Based on the Schiff Base Reaction, Analytical Chemistry, 2022, 94: 14143-14150. Baofu Ma, Jianyu Han, Kun Zhang, Qike Jiang, Zhigang Sui, Zhixin Zhang*, Baofeng Zhao*, Zhen Liang, Lihua Zhang, Yukui Zhang, Targeted Killing of Tumor Cells based on Isoelectric Point Suitable Nanoceria-rod with High Oxygen Vacancies, Journal of Materials Chemistry B, 2022, 10: 1410-1417. Lukuan Liu, Jianhui Liu, Wen Zhou, Zhigang Sui, Jing Liu, Kaiguang Yang*, Lihua Zhang*, Zhen Liang, Yukui Zhang, An Artificial Antibody for Exosome Capture by Dull Template Imprinting Technology, Journal of Materials Chemistry B, 2022, 10: 6655-6663. Yuwen Chen#, Yuxin An#, Zhongpeng Dai, Yi Liu, Zhen Liang, Qun Zhao*, Lihua Zhang*, Yukui Zhang, Highly Selective Enrichment of Surface Proteins from Living Cells by Photo-crosslinking Probe Enabled In-depth Analysis of Surfaceome, Analytica Chimica Acta, 2022, 1203: 339694. Zhiting Wang#, Chao Liu#, Songduo Wang, Xinhang Hou, Pengyun Gong, Xiao Li, Zhen Liang, Jianhui Liu*, Lihua Zhang*, Yukui ZhangSegmented MS/MS acquisition of a1 ion-based strategy for in-depth proteome quantitation, Analytica Chimica Acta, 2022, 1232: 340491. Yechen Hu, Bo Jiang*, Jianhui Liu, He Wang, Zhigang Sui, Baofeng Zhao, Zhen Liang, Lihua Zhang*, Yukui Zhang, Zn(II)-DPA Functionalized Graphene Oxide Two-dimensional Nanocomposites for N-phosphoproteins Enrichment, Talanta, 2022, 243: 123384. Weijie Zhang#, Chao Yang#, Jianhui Liu, Zhen Liang, Yichu Shan*, Lihua Zhang*, Yukui Zhang, Accurate Discrimination of Leucine and Isoleucine Residues by Combining Continuous Digestion with Multiple MS3 Spectra Integration in Protein Sequence, Talanta, 2022, 249: 123666. Lili Zhao#, Bowen Zhong#, Yuxin An, Weijie Zhang, Hang Gao, Xiaodan Zhang, Zhen Liang, Yukui Zhang, Qun Zhao*, Lihua Zhang*, Enhanced protein–protein interaction network construction promoted by in vivo cross-linking with acid-cleavable click-chemistry enrichment, Frontiers in Chemistry, 2022, 10: 994572. Liping Chen#, Ping Guo#, Wenxue Li#, Xinhang Jiang, Qun Zhao, Daochuan Li, Qing Wang, Yongmei Xiao, Xiumei Xing, Yaqin Pang, Michael Aschner, Lihua Zhang*, Wen Chen*, Protein Phosphatase 2A Regulates Cytotoxicity and Drug Resistance by Dephosphorylating AHR and MDR1, Journal of Biological Chemistry, 2022, 298: 101918. Nan Zhao, Dan Liu, Yi Wang , Xiaozhe Zhang*, Lihua Zhang, Screening and identification of anti-acetylcholinesterase ingredients from Tianzhi granule based on ultrafiltration combined with ultra-performance liquid chromatography-mass spectrometry and in silico analysis, Journal of Ethnopharmacology, 2022, 298: 115641. Zhigang Sui#, Xiaoyao Song#, Yujie Wu#, Rui Hou, Jianhui Liu, Baofeng Zhao, Zhen Liang, Jiping Chen, Lihua Zhang*, Yukui Zhang, The Cytotoxicity of PM2.5 and Its Effect on the Secretome of Normal Human Bronchial Epithelial Cells, Environmental Science and Pollution research, 2022, 29: 75966-75977. Rui Hou, Linhui Gao, Jianhui Liu, Zhen Liang, Yongjin J. Zhou*, Lihua Zhang*, Yukui Zhang, Comparative Proteomics Analysis of Pichia Pastoris Cultivating in Glucose and Methanol, Synthetic and Systems Biotechnology, 2022, 7: 862-868. Siqi Zhang, Xiao Ma, Hailong Yu, Xinyi Lu, Jianhui Liu, Lihua Zhang, Guangyao Wang, Junwei Ye*, Guiling Ning*, Silver(i) Metal-organic Framework-embedded Polylactic Acid Electrospun Fibrous Membranes for Efficient Inhibition of Bacteria, Dalton Transactions, 2022, 51: 6673-6681. Jialei Wu#, Jianhui Liu#, Anquan Ji, Dongsheng Ding, Guiqiang Wang, Yao Liu, Lihua Zhang*, Lei Feng*, Jian Ye*, Deep Coverage Proteome Analysis of Hair Shaft for Forensic Individual Identification, Forensic Science International: Genetics, 2022, 60: 102742. Shuai Huang, Xinxin Liu, Dan Liu*, Xiaozhe Zhang*, Lihua Zhang, Weidong Le, and Yukui Zhang, Pyrylium-Based Derivatization for Rapid Labeling and Enhanced Detection of Cholesterol in Mass Spectrometry Imaging, Journal of the American Society for Mass Spectrometry, 2022, 33: 2310-2318. Meixi He, Yingang Feng, Yi Wang, Mengchun Cheng, Xiaozhe Zhang*, Lihua Zhang, Discovery of a cysteine-rich peptide with glycation modification from Achyranthes bidentata Blume, Fitoterapia, 2022, 163: 105338. 陈玉宛,周雯,李欣蔚,杨开广*,梁振,张丽华*,张玉奎,基于液质联用技术的蛋白质-蛋白质相互作用研究进展,化学学报,2022,80:817-826。 Wang Wan#, Qun Zhao#, Biao Jing#, Congcong Peng, Mengdie Wang, Yanan Huang, Wenhan Jin, Bowen Zhong, Zhenduo Zhang, Xuepeng Dong, Zhenming Gao*, Lihua Zhang*, Yu Liu*, Interrogating the impact of aggregation-induced emission nanoparticles on in vitro protein stability, ex vivo protein homeostasis, and in vivo biocompatibility, AGGREGATE, 2022, e274. Lili Zhao, Zhou Gong, Qun Zhao*, Lihua Zhang*, Yukui Zhang, Deciphering In-vivo Cross-linking Mass Spectrometry Data for Dynamic Protein Structure Analysis, Chemical Research in Chinese Universities, 2022, 38: 758-762. 李洋,单亦初,梁振*,张丽华,张玉奎,SUMO化蛋白质组的富集策略研究进展,分析测试学报,2022,41:58-62。 褚宏伟,郑诗颖,赵群,赵宝锋,梁振,张丽华*,张玉奎,膜蛋白质复合物提取方法研究进展,分析测试学报,2022,41:1387-1394。 韩若楠#,赵丽丽#,安雨馨,梁振,赵群∗,张丽华,张玉奎,基于镜像酶正交酶切的蛋白质复合物规模化精准分析新方法,色谱,2022, 40:224-233。 周雯,杨开广*,张丽华*,梁振,张玉奎,基于成簇的规则间隔短回文重复序列的严重急性呼吸综合征冠状病毒2检测的最新进展,色谱,2022,40:773-781.  贺映云,袁辉明,梁振,张丽华,张玉奎, 单细胞蛋白质组学分析技术研究进展,分析实验室,2022,41:1365-1378. Liping Chen#, Ping Guo#, Wenxue Li#, Fei Fang#, Wei Zhu, Junling Fan, Fangping Wang, Yuanyuan Gao, Qun Zhao, Qing Wang, Yongmei Xiao, Xiumei Xing, Daochuan Li, Tieliu Shi, Dianke Yu, Michael Aschner, Lihua Zhang*, Wen Chen*, Perturbation of Specific Signaling Pathways Is Involved in Initiation of Mouse Liver Fibrosis, Hepatology, 2021, 73: 1551-1569. Wang Wan, Yanan Huang, Qiuxuan Xia, Yulong Bai, Yuwen Chen, Wenhan Jin, Mengdie Wang, Di Shen, Haochen Lyu, Yuqi Tang, Xuepeng Dong, Zhenming Gao, Qun Zhao, Lihua Zhang, Yu Liu*, Covalent Probes for Aggregated Protein Imaging via Michael Addition,Angewandte Chemie-International Edition, 2021, 60: 11335-11343. Huiming Yuan*, Zhongpeng Dai, Xiaodan Zhang, Baofeng Zhao, Hongwei Chu, Lihua Zhang*, Yukui Zhang, Fully Automated Sample Treatment Method for High Throughput Proteome Analysis, Science China-Chemistry, 2021, 64: 313-321. Yilan Li,# Kaiguang Yang#, Huiming Yuan*, Weijie Zhang, Zhigang Sui, Nan Wang, Hongli Lin, Lihua Zhang*, Yukui Zhang, Surface Nanosieving Polyether Sulfone Particles with Graphene Oxide Encapsulation for the Negative Isolation toward Extracellular Vesicles, Analytical Chemistry, 2021, 93: 16835-16844. Yilan Li, Huiming Yuan*, Zhongpeng Dai, Weijie Zhang, Xiaodan Zhang, Baofeng Zhao, Zhen Liang, Lihua Zhang*, Yukui Zhang, Integrated Proteomic Sample Preparation with Combination of On-line High-abundance Protein Depletion, Denaturation, Reduction, Desalting and Digestion to Achieve High Throughput Plasma Proteome Quantification, Analytica Chimica Acta, 2021, 1154: 338343. Yang Li#, Mingwei Sun#, Yechen Hu, Yichu Shan*, Zhen Liang, Lihua Zhang*, Yukui Zhang, Antibody-free Enrichment Method for Proteome-wide Analysis of Endogenous SUMOylation Sites, Analytica Chimica Acta, 2021, 1154: 338324. Ju Liu, Yanlei Wang*, Chenlu Wang, Jinai Gao, Wei Cui, Baofeng Zhao, Lihua Zhang, Hongyan He*, Suojiang Zhang*, Thermodynamical Origin of Nonmonotonic Inserting Behavior of Imidazole Ionic Liquids into the Lipid Bilayer, Journal of Physical Chemistry Letters, 2021, 12; 9926-9932. Yuanbo Chen#, Bo Jiang#, Huiming Yuan*, Xudong Zhu, Jianhui Liu, Xiaodan Zhang, Zhen Liang, Liming Wang, Lihua Zhang*, Yukui Zhang, Fully Integrated Protein Absolute Quantification Platform for Analysis of Multiple Tumor Markers in Human Plasma, Talanta, 2021, 226: 122102. Hongwei Chu, Changqing Wu, Qun Zhao, Rui Sun, Kuo Yang, Baofeng Zhao*, Yang Liu, Zhen Liang, Shijun Zhong, Lihua Zhang*, Yukui Zhang, Quantitative Proteomics Identifies FOLR1 to Drive Sorafenib Resistance via Activating Autophagy in Hepatocellular Carcinoma Cells, Carcinogenesis, 2021, 42: 753-761. Xiangdong Li, Yihui Chen, Shubing Chen, Chunyan Hou, Rongrong Xuan, Yajie Gao, Shuaijun Ren, Lihui Yao, Tingting Wang*, Lihua Zhang, Yukui Zhang, Polyethyleneimine-functionalized Fe3O4/attapulgite Particles for Hydrophilic Interaction-based Magnetic Dispersive Solid-phase Extraction of Fluoroquinolones in Chicken Muscle, Analytical and Bioanalytical Chemistry, 2021, 413: 3529-3540. Lubei Dong, Yihui Chen, Shubing Chen, Chunyan Hou, Shangyou Wang, Rongrong Xuan, Keyi Fang, Tingting Wang*, Lihua Zhang, Yukui Zhang, Novel Synthesized Attapulgite Nanoparticles-based Hydrophobic Monolithic Column for in-tube Solid-phase Microextraction of Thiosildenafil, Pseudovardenafil, and Norneosildenafil in Functional Foods, Analytical and Bioanalytical Chemistry, 2021, 413: 1871-1882. Yechen Hu, Hao Jiang, Baofeng Zhao*, Kaiguang Yang, Zhen Liang, Lihua Zhang*, Yukui Zhang, Quantitative Proteomics of Epigenetic Histone Modifications in MCF-7 Cells Under Estradiol Stimulation, Analytical Methods, 2021, 13: 469-476. Chao Yang, Jianhui Liu, Weijie Zhang, Yichu Shan*, Zhongpeng Dai, Lihua Zhang*, Yukui Zhang, Peptides De Novo Sequencing Strategy Based on Pseudo Isobaric Peptide Termini Labeling, Chinese Journal of Analytical Chemistry, 2021, 49: 366-376. 周雯, 杨开广, 张丽华*, 张玉奎, 活性氧刺激响应纳米载体,色谱, 2021,39:118-124。 郑诗颖, 褚宏伟, 赵群, 赵宝锋, 张丽华*, 张玉奎, 基于离子液体的蛋白质组样品制备新方法研究进展,中国科学·化学,2021,51:1373-1381。 韩若楠#,赵丽丽#,安雨馨,梁振,赵群*,张丽华,张玉奎,基于镜像酶正交酶切的蛋白质复合物规模化精准分析新方法,色谱,2021,暂时无页码。 杨超,单亦初*,张玮杰,戴忠鹏,张丽华*,张玉奎,基于非特异性蛋白酶连续酶解的蛋白质全序列测定方法,化学学报,2021,79:663-669。 邵文亚,梁玉,刘键熙,刘洪涛,王钊伟,随志刚,赵宝锋,张晓丹,梁振,张丽华*,张玉奎,基于EThcD 质谱碎裂的O-GlcNAc 糖基化位点定量分析方法及其在高脂喂养小鼠肝脏糖蛋白质组分析中的应用,分析化学,2021,12:2106-2116。

推荐链接
down
wechat
bug