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个人简介

主要教育、科研简历 1991 – 1995 华东理工大学、生物工程系、生物化工专业、学士学位 1995 – 2001 华北制药集团新药研究中心 2001 – 2006 中科院上海生命科学研究院、生化与分子生物学专业、博士学位 2006 – 2008 北京航空航天大学、生物工程系、博士后 2008 – 北京航空航天大学、生物与医学工程学院、副教授 科研项目 流型对动脉血管内皮细胞连接蛋白的影响及机制研究 (国家自然科学基金面上项目, 2018.01-2021.1,项目负责人) 流型对动脉血管的基底膜基质表达和装配的影响机制研究 (国家自然科学基金面上项目,2012.01-2015.12,项目负责人) 具有生理功能的微反应器 (国家自然科学基金国家重大科研仪器研制项目,2019.01-2023.12,主要研究人员) 基于血管化的复杂组织工程化构建(国家 研发计划2016.7-2020.12,主要研究人员) 支架、关节、人造血管等高端植介入重大产品研发 子课题项目‘小口径人造血管’ (科技部国家科技支撑计划,2012.01-2015.12,主要研究人员)

研究领域

血管力学生物学 心血管再生医学 血流动力学 干细胞 生物工程(生物制药)

近期论文

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Gong X, Liu H, Ding X, Liu M, Li X, Zheng L, Jia X, Zhou G, Zou Y, Li J, Huang X, Fan Y. Physiological pulsatile flow culture conditions to generate functional endothelium on a sulfated silk fibroin nanofibrous scaffold. Biomaterials. 2014 Jun;35(17):4782-91. (IF2019 10.317,Q1) Gong X, Hou Z, Endsley MP, Gronseth EI, Rarick KR, Jorns JM, Yang Q, Du Z, Yan K, Bordas ML, Gershan J, Deepak P, Geethadevi A, Chaluvally-Raghavan P, Fan Y, Harder DR, Ramchandran R, Wang L. Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes. NPJ Precis Oncol. 2019 Oct 3;3:24. (IF2019 7.717,Q1) Gong X, Liang Z, Yang Y, Liu H, Ji J, Fan Y. A resazurin-based, nondestructive assay for monitoring cell proliferation during a scaffold-based 3D culture process. Regen Biomater. 2020 Jun;7(3):271-281. (IF2019 4.882,Q2) Gong X, Li B, Yang Y, Huang Y, Sun Y, Liu M, Jia X, Fan Y. Bone marrow derived endothelial progenitor cells retain their phenotype and functions after a limited number of culture passages and cryopreservation. Cytotechnology. 2019 Feb;71(1):1-14. (IF2019 1.777,Q4) Gong X, Zhao X, Li B, Sun Y, Liu M, Huang Y, Jia X, Ji J, Fan Y. Quantitative Studies of Endothelial Cell Fibronectin and Filamentous Actin (F-Actin) Coalignment in Response to Shear Stress. Microsc Microanal. 2017 Oct;23(5):1013-1023. (IF2019 3.414,Q1) Gong X, Yao J, He H, Zhao X, Liu X, Zhao F, Sun Y, Fan Y. Combination of flow and micropattern alignment affecting flow-resistant endothelial cell adhesion. J Mech Behav Biomed Mater. 2017 Oct;74:11-20. (IF2019 3.372,Q2) Liu H, Gong X, Jing X, Ding X, Yao Y, Huang Y, Fan Y. Shear stress with appropriate time-step and amplification enhances endothelial cell retention on vascular grafts. J Tissue Eng Regen Med. 2017 Nov;11(11):2965-2978. (IF2019 3.078,Q2) Li X, Gong X, Zhu L, Leng J, Fan Q, Sun D, Lang J, Fan Y. Stretch magnitude- and frequency-dependent cyclooxygenase 2 and prostaglandin E2 up-regulation in human endometrial stromal cells: possible implications in endometriosis. Exp Biol Med. 2012 Nov;237(11):1350-8. (IF2019 3139,Q2) Gong X, Li D, Li X, Fang Q, Han X, Wu Y, Yang S, Shen BQ. Fed-batch culture optimization of a growth-associated hybridoma cell line in chemically defined protein-free media. Cytotechnology. 2006 Sep;52(1):25-38. (IF2019 1.777,Q4) Gong X, Fang Q, Li X, Han X, Wu Y, Yang S, Shen BQ. A High-throughput End-point Assay for Viable Mammalian Cell Estimation. Cytotechnology. 2005 Sep;49(1):51-8. (IF2019 1.777,Q4)

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