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个人简介

主要教育、科研简历 1988 - 1993 华中科技大学同济医学院(同济医科大学) 预防医学专业 学士学位 1993 - 1995 湖北民族学院 医学院 教师 1995 - 1998 华中科技大学同济医学院(同济医科大学) 毒理学专业 硕士学位 1998 - 2001 北京大学医学部 毒理学专业 博士学位 2001 - 2003 清华大学 生物科学与技术系 博士后 2004 - 2008 北京航空航天大学 生物工程系 副教授。 2008- 北京航空航天大学 生物与医学工程学院 副教授 主要学术荣誉 北京航空航天大学蓝天计划科研类“蓝天新星”(2005) 北京市科技新星(2006)

研究领域

航空航天医学与空间生命科学 分子与细胞毒理学与药理学 肿瘤生物学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Xiao-Fei Li, Xiao-Rong Wu, Ming Xue, Yan Wang, Jie Wang, Yang Li, Suriguga, Guang-Yao Zhang, Zong-Chun Yi*. The role of DNA methylation in catechol-enhanced erythroid differentiation of K562 cells. Toxicology and Applied Pharmacology. 2012; 265 (1): 43–50. Xiao-Rong Wu, Ming Xue, Xiao-Fei Li, Yan Wang, Jie Wang, Qing-Ling Han, Zong-Chun Yi*. Phenolic metabolites of benzene inhibited the erythroid differentiation of K562 cells. Toxicology Letters. 2011; 203 (3): 190-199. Zong-Chun Yi*, Xiao-Fei Li, Yan Wang, Jie Wang, Yan Sun, Feng-Yuan Zhuang. The postmitotic Saccharomyces cerevisiae after spaceflight showed higher viability. Advances in Space Research.2011; 47 (11): 2049–2057. Zong-Chun Yi, Bing Xia, Guang-Yao Zhang, Ming Xue, Hong Wang, Hui-Min Zhou, Yan Sun, Feng-Yuan Zhuang. Simulated microgravity inhibits the proliferation of K562 erythroleukemia cells but does not result in apoptosis. Advances in Space Research.2009; 44: 233-44. Zong-Chun Yi, Yan-Ze Liu, Hai-Xia Li, Zhao Wang. Chebulinic acid and tellimagrandin I inhibit DNA strand breaks by hydroquinone/Cu(II) and H2O2/Cu(II), but potentiate DNA strand breaks by H2O2/Fe(II). Toxicology in Vitro. 2009; 23(4): 667–673. Zong-Chun Yi, Yan-Ze Liu, Hai-Xia Li, Zhao Wang. Prooxidant action of chebulinic acid and tellimagrandin I: causing copper-dependent DNA strand breaks. Toxicology in Vitro.2009; 23(3): 425–431. Zong-Chun Yi, Hong Wang, Guang-Yao Zhang, Bing Xia. Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation. Oral Oncology. 2007; 43: 898-904. Zong-chun Yi,Yan-Ze Liu, Hai-Xia Li, Yan Yin, Feng-Yuan Zhuang, Yu-Bo Fan, Zhao Wang. Tellimagrandin I enhances gap junctional communication and attenuates the tumor phenotype of human cervical carcinoma HeLa cells in vitro. Cancer Letters.2006; 242: 77-87. Zongchun Yi, Zhao Wang, Haixia Li, Mingjie Liu. Inhibitory effect of tellimagrandin I on chemically induced differentiation of human leukemia K562 cells. Toxicol Letters. 2004; 147: 109–19. Zong-chun Yi, Zhao Wang, Hai-xia Li, Ming-jie Liu, Rong-cong Wu, Xiao-hui Wang. Inhibitory of Chebulinic Acid on Differentiation of Human Leukemia K562 Cells. Acta pharmacologica Sinica. 2004: 25(2): 231-8. Zong-chun Yi, Min Zhang, Juan-lin Fu, Zhao Wang, Zong-can Zhou. Down-Regulation of Mitotic Checkpoint Function in Transformed Human Embryo Lung Fibroblasts Induced by N-Methyl-N’-nitro-N-nitrosoguaridine. Chinese Medical Journal.2004; 117: 1079-83. Li-xue Zou, Shao-yan Cui, Jian Zhong, Zong-chun Yi, Yan Sun, Yu-bo Fan, Feng-yuan Zhuang. Upregulation of erythropoietin receptor in UT-7/EPO cells inhibits simulated microgravity-induced cell apoptosis. Advances in Space Research. 2011; 48 (2): 390–394. Chen Zhao, Yan Sun, Zong-Chun Yi, Long Rong, Feng-Yuan Zhuang, Yu-Bo Fan. Simulated microgravity inhibits cell wall regeneration of Penicillium decumbens protoplasts. Advances in Space Research.2010; 46: 701–6. Li-Xue Zou, Shao-Yan Cui, Jian Zhong, Zong-Chun Yi, Yan Sun, Yu-Bo Fan, Feng-Yuan Zhuang.Simulated microgravity induce apoptosis and down-regulation of erythropoietin receptor of UT-7/EPO cells. Advances in Space Research.2010; 46: 1237-44. Chi Wang, Chen Sang, Akira Higashibata, Noriaki Ishiok, Long Rong, Chun Yang, Yan Sun, Zong-Chun Yi, Feng-Yuan Zhuang. Changes of muscle-related genes and proteins after spaceflight in Caenorhabditis elegans. Progress in Biochemistry and Biophysics. 2008, 35(10): 1195-1201. Chi Wang, Chen Sang, Chun Yang, Yan Sun, Zong-Chun Yi, Feng-Yuan Zhuang. Mechanisms of Muscular Atrophy and Gravisensing After Simulated Microgravity in Caenorhabditis elegans: Parallel Control to Spaceflight Research in C. elegans. Progress in Biochemistry and Biophysics. 2008, 35(11): 1298-1304. (In Chinese)

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