个人简介
教育背景
2005.09-2010.06 天津大学，材料学专业，博士，硕-博连读
2001.09-2005.07 郑州大学，高分材料科学与工程专业，学士
工作经历
2016.10-至今 中国医学科学院药物研究所药物制剂室，副研究员
2014.09-2016.09 中国医学科学院药物研究所药物制剂室，助理研究员
2012.10-2014.08 军事医学科学院毒物药物研究所，药剂学博士后
研究领域
1. 基于肿瘤微环境的智能药物递送载体设计
2. siRNA递送及肿瘤免疫微环境靶向制剂
3. 药物新型释药系统研究
近期论文
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1. Yang Yanfang, Yang Yang, Xie Xiangyang, et al. PEGylated liposomes with NGR ligand and heat-activable cell penetrating peptide-doxorubicin conjugate for tumor-specific therapy, Biomaterials 2014, 35(14): 4368-4381.
2. Yang Yanfang, Meng Yingying, Ye Jun, et al. Sequential delivery of VEGF siRNA and paclitaxel for PVN destruction, antiangiogenesis, and tumor cell apoptosis procedurally via a multi-functional polymer micelle, Journal of Controlled release 2018, 287: 103-120.
3. Yang Yanfang, Yang Yang, Xie Xiangyang, et al. Dual stimulus of hyperthermia and intracellular redox environment triggered release of siRNA for tumor-specific therapy, International Journal of Pharmaceutics 2016, 506: 158-173.
4. Yang Yanfang, Xia Xuejun, Dong Wujun, et al. Acid Sensitive Polymeric Micelles Combining Folate and Bioreducible Conjugate for Specific Intracellular siRNA Delivery, Macromolecular Bioscience 2016, 16: 759-773.
5. Yang Yanfang, Ye Jun，Ma Panpan, et al. Folate and CPP mediated specific delivery of camptothecin to tumor via pH and reduction dual-sensitive micelles, Journal of Controlled release 2017, 259: e164-e165.
6. Yang Yanfang, Xie Xiangyang, Xu Xueqing, et al. Thermal and magnetic dual-responsive liposomes with acell-penetrating peptide-siRNA conjugate for enhanced and targeted cancer therapy, Colloids and Surfaces B: Biointerfaces 2016, 146: 607-615.
7. Yang Yanfang, Xie Xiangyang, Yang Yang, et al. Photo-Responsive and NGR-Mediated Multifunctional Nanostructured Lipid Carrier for Tumor-Specific Therapy, Journal of Pharmaceutical Sciences 2015, 104: 1328-1339.
8. Xie Xiangyang#，Yang Yanfang#, Yang Yang, et al. Photolabile-caged peptide-conjugated liposomes for siRNA delivery, Journal of Drug Targeting 2015, 23: 789-799.
9. 杨艳芳#, 孟盈盈#，叶军等. 模拟体内肿瘤微环境的乳腺癌细胞与脐静脉内皮细胞的体外共培养，药学学报2018, 53: 403-409.
10. 刘东东, 孟盈盈, 叶军, 刘玉玲, 杨艳芳*. 绿原酸长循环脂质体中绿原酸含量测定方法的建立, 中国药师, 2019, 22(3): 429~433
11. 杨艳芳，谢向阳，杨阳等. 粒径与表面电荷影响脂质体体内药物靶向递送的研究进展，药学学报2013, 48: 1644-1650.
12. Yang Yang，Yang Yanfang, Xie Xiangyang, et al. Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRNA targeting delivery, Biomaterials 2015, 48: 84-96.
13. Meng Luhua, Xia Xuejun, Yang Yanfang, et al. Co-encapsulation of paclitaxel and baicalein in nanoemulsions to overcome multidrug resistance via oxidative stress augmentation and P-glycoprotein inhibition, International Journal of Pharmaceutics 2016, 513: 8-16.
14. Ye Jun, Dong Wujun, Yang Yanfang, et al. Vitamin E-rich nanoemulsion enhances the antitumor efficacy of low-dose paclitaxel by drivingTh1 immune response, Pharmaceutical Research, 2017, 34: 1244~1254.
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