张蕾磊 - 中国医学科学院药物研究所 -

个人简介

教育背景 2005.9-2008.7 中国医学科学院药物研究所药物化学博士 2001.9-2004.7 山东省医学科学院药物研究所天然药物化学硕士 1997.9-2001.7 山东大学药学院药学学士工作经历 2017.10-至今中国医学科学院药物研究所副研究员 2008.9-2017.9 中国医学科学院药物研究所助理研究员 2004.9-2005.7 山东省医学科学院药物研究所实习研究员

研究领域

1. 质谱分析应用研究 2. 有机小分子探针生物成像应用研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Rao Wei#, Leilei Zhang#, Shengnan Xu, Qingyang Zhang, Yongxiu Qi, Hai-yu Hu*. A single component self-assembled thermally activated delayed fluorescence nanoprobe. Chem Commun (Camb). 2020, 56(17), 2550-2553. 2. Leilei Zhang#, Yun Liu#, Qingyang Zhang, Tiegang Li, Min Yang, Qingqiang Yao, Xilei Xie, Hai-Yu Hu*. Gadolinium-Labeled Aminoglycoside and Its Potential Application as a Bacteria-Targeting Magnetic Resonance Imaging Contrast Agent. Anal Chem. 2018, 90(3), 1934-1940. 3. Leilei Zhang, Yan Yu, Zijie Liu, Zeper Abliz, Gang Liu*. Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays. Journal of Medicinal Chemistry, 2009, 52, 4419-4428. 4. Yun Liu#, Leilei Zhang*#, Marc Nazare, Qingqiang Yao, Hai-Yu Hu*. A Novel Nitroreductase-enhanced MRI Contrast Agent and its Potential Application in Bacterial Imaging. Acta Pharmaceutica Sinica B, 2018, 8(3), 401-408. 5. Leilei Zhang, Tianming Yang, Xilei Xie, Gang Liu*. Identification of 3, 5, 6-substituted indolin-2-one’s inhibitors of aurora B by development of a luminescent kinase assay. Bioorganic ＆Medicinal Chemistry Letters, 2015, 25, 2937-2942. 6. Leilei Zhang*#, Yan Wang#, Dequan Yu*. Simultaneous quantification of six major triterpenoid saponins in Schefflera kwangsiensis using high-performance liquid chromatography coupled to orbitrap mass spectrometry. Natural product research, 2015, 29, 1350-1357. 7. Leilei Zhang, Shengquan Hu, Lei Lei, Yuliang Zhang, Lijing Zhang, Hongrui Song, Zhufang Shen, Zhiqiang Feng*. Design, Synthesis and Evaluation of Novel Derivatives of Orotic Acid Amide as Potent Glucokinase Activators. Letters in Drug Design & Discovery, 2017, 14, 252- 261. 8. Leilei Zhang, Zhiqiang Feng*. The stereoselective C-alkylation of chiral nitronic acid (4S﹡, 5R)-(+)-4-(6-nitro-6-carbethoxymethyl)-5-[(1R)-menthyloxy]-3,4-dihydro-2(5H)-furanone. J. Indian Chem. Soc., 2014, 91, 1335-1339. 9. 张蕾磊，薛海，李莉，陆小凡，陈志伟，刘刚*. (±)-F18对映异构体的HPLC手性分离、绝对构型确定以及抗HIV-1活性研究。药学学报，2015，50， 733-737.