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个人简介

教育背景 1990-1995 河北医科大学 临床医学专业 本科 1999-2002 天津医科大学 内分泌与代谢病专业 硕士 2007-2010 北京协和医学院 药理学专业 博士 工作经历 1995-1999 河北省沧州中西医结合医院 住院医师 2002-2004 天津天士力集团研究院 临床研究专员 2004-2007 康辰医药股份有限公司 临床研究项目经理 2010-2012 航天中心医院 助理研究员 2012-2013 美国艾默里大学 博士后 2013-2016 美国伊利诺伊大学 博士后 2016-2017 中国医学科学院药物研究所 助理研究员 2017-至今 中国医学科学院药物研究所 研究员

研究领域

代谢病药理学:肥胖与糖尿病的基础研究,高通量筛选与新药发现

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Qiang G, Whang Kong H, Gil V, Liew CW. Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction. Sci Rep. 2017,7:40215. 2. Qiang G, Whang Kong H, Xu S, Pham HA, Parlee SD, Burr AA, Gil V, Pang J, Hughes A, Gu X, Fantuzzi G, MacDougald OA, Liew CW. Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation. Mol Metab. 2016,5(7):480-490. 3. Qiang G, Kong WH, Fang D, McCann M, Yang X, Du G, Blüher M, Zhu J, Liew CW. The obesity-induced transcriptional regulator TRIP-Br2, mediates visceral fat endoplasmic reticulum stress-induced inflammation. Nat Commun.2016, 7:11378. 4. Qiang GF*,Yang XY*, Shi LL, Zhang HA, Chen BN, Zhao Y, Zu M, Zhou D, Guo J, Yang HG, Zhang L, Du GH. Antidiabetic effect of Salvianolic acid A on diabetic animal models via AMPK activation and mitochondrial regulation. Cell Physiol Biochem. 2015,36:395-408. (*Co-first author) 5. Qiang G, Xue S, Yang JJ, Du G, Pang X, Li X, Goswami D, Griffin PR, Ortlund EA, Chan CB, Ye K. Identification of a small molecular insulin receptor agonist with potent antidiabetes activity. Diabetes. 2014,63(4):1394-1409. 6. Qiang GF*, Yang XY*, Xuan Q, Shi LL, Zhang HA, Chen BN, Li XX, Zu M, Zhou D, Guo J, Yang HG, Zhang L, Du GH. Salvianolic acid A prevents the pathological progression of hepatic fibrosis in high-fat diet-fed and streptozotocin-induced diabetic rats. Am J Chin Med. 2014, 42(5):1183-1198. (*Co-first author) 7. Qiang GF*, Zhang L*, Yang XY, Xuan Q, Shi LL, Zhang HA, Chen BN, Li XX, Zu M, Zhou D, Guo J, Yang HG, Du GH. Effect of valsartan on the pathological progression of hepatic fibrosis in rats with type 2 diabetes. Eur J Pharmacol. 2012,685(1-3):156-164. (*Co-first author) 8. Yang XY*, Qiang GF*, Zhang L, Zhu XM, Wang SB, Sun L, Yang HG, Du GH. Salvianolic acid A protects against vascular endothelial dysfunction in high-fat diet-fed and streptozotocin-induced diabetic rats. J Asian Nat Prod Res. 2011, 13(10):884-894. (*Co-first author) 9. Hou B, Zhao Y, Qiang G, Yang X, Xu C, Chen X, Liu C, Wang X, Zhang L, Du G. Puerarin Mitigates Diabetic Hepatic Steatosis and Fibrosis by Inhibiting TGF-β Signaling Pathway Activation in Type 2 Diabetic Rats. Oxid Med Cell Longev. 2018:4545321. 10. Qi W, Keenan HA, Li Q, Ishikado A, Kannt A, Sadowski T, Yorek MA, Wu IH, Lockhart S, Coppey LJ, Pfenninger A, Liew CW, Qiang G, Burkart AM, Hastings S, Pober D, Cahill C, Niewczas MA, Israelsen WJ, Tinsley L, Stillman IE, Amenta PS, Feener EP, Vander Heiden MG, Stanton RC, King GL. Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. Nat Med. 2017,23(6):753-762. 11. Hou B, Qiang G, Zhao Y, Yang X, Chen X, Yan Y, Wang X, Liu C, Zhang L, Du G. Salvianolic Acid A Protects Against Diabetic Nephropathy through Ameliorating Glomerular Endothelial Dysfunction via Inhibiting AGE-RAGE Signaling. Cell Physiol Biochem. 2017,44(6):2378-2394. 12. El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN. SerpinB1 Promotes Pancreatic β Cell Proliferation. Cell Metab. 2016,23(1):194-205. 13. Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells. Proc Natl Acad Sci U S A. 2014,111(22): E2319-2328. 14. Yang XY, Sun L, Xu P, Gong LL, Qiang GF, Zhang L, Du GH. Effects of salvianolic scid A on plantar microcirculation and peripheral nerve function in diabetic rats. Eur J Pharmacol. 2011,665 (1-3):40-46.

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