陆平 - 复旦大学

个人简介

EDUCATION 2012.04-2016.05 Postdoctoral Fellowship, University of California, Santa Barbara, USA (PI: Prof. Armen Zakarian) 2010.02-2012.04 Alexander von Humboldt Postdoctoral Fellowship, Technische Universität München, Germany, (Host: Prof. Thorsten Bach) 2004.09-2009.12 Ph.D., Shanghai Institute of Organic Chemistry, CAS, China(Advisor: Prof. Shengming Ma) 1999.9-2004.07 Bachelor in Chemistry, University of Science and Technology of China(Advisors: Prof. Shengming Ma & Prof. Guanwu Wang) Awards Presidential Award for the Outstanding Student (CAS, 2009) Alexander von Humboldt Foundation (2010.2-2012.4) Shanghai Natural Sciences, the First Prize (2011) Recruitment Program of Global Youth Experts (2016-2019) Thieme Chemistry Journals Award (2017）

研究领域

Synthesis of Strained Molecules and Applications Cycloaddition Photoinduced Cycloaddition, Diels-Alder Reaction, 1,3-Dipolar Reaction… Functionalization C-H functionalization, Conjugate Addition, Desymmetrization… Applications of strain releasing of small-ring intermediates Synthesis of Bioactive Compounds and Natural Products

近期论文

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Aspirin-Mediated Acetylation of SIRT1 Maintains Intestinal Immune Homeostasis. Liangguo Xie, Chaoqun Li, Chao Wang, Zhen Wu, Changchun Wang, Chunyu Chen, Xiaojian Chen, Dejian Zhou, Qiang Zhou, Ping Lu, Chen Ding, Chen-Ying Liu, Jinzhong Lin, Xumin Zhang, Xiaofei Yu,* Wei Yu* Adv. Sci. 2024, 2306378. Palladium-Catalyzed Divergent Enantioselective Functionalization of Cyclobutenes. Zhonggui Wang,§ Jie Zhu,§ Minyan Wang,* and Ping Lu*J. Am. Chem. Soc., 2024, 10.1021/jacs.4c02215. Enantioselective Hydrofunctionalization of Cyclobutenones: Total Synthesis of gem-Dimethylcyclobutane Natural Products. Shaowei Wang+, Changxu Zhong+, Yingchao Huang, and Ping Lu*Angew. Chem. Int. Ed. 2024, e202400515. Enantioselective Intramolecular ortho Photocycloaddition Reactions of 2-Acetonaphthones. Peng Yan, Simone Stegbauer, Qinqin Wu, Elena Kolodzeiski, Christopher J. Stein, Ping Lu,* and Thorsten Bach*Angew. Chem. Int. Ed. 2024, 63, e202318126. Modular Synthesis of Multi substituted Cyclobutanones Enabled by Oxyallyl Cations. Meng Wang, Zhonggui Wang, and Ping Lu*Chin. J. Chem. 2024, 42, 459–463. (Dedicated to the Memory of Professor Xiyan Lu) Collective Synthesis of Chiral Tetrasubstituted Cyclobutanes Enabled by Enantioconvergent Negishi Cross-Coupling of Cyclobutenones. Min Yan+, Qiang Zhou+, and Ping Lu*Angew. Chem. Int. Ed. 2023, 62, e202218008. Enantioselective [3+2]-cycloaddition of 2,3-disubstituted cyclobutenones: vicinal quaternary stereocenters construction and skeletal functionalization. Licheng Lu, and Ping Lu*Chem. Sci., 2023, 14, 8355–8359 Enantioselective Construction of Vicinal Angular Quaternary Stereocenters Enabled by Strained Cyclobutenones. Peng Yan, Jia Zhang, Licheng Lu, Huayi Fang, and Ping Lu*ACS Catal. 2022, 12, 15416−15423 Diastereoselective synthesis of 1,1,3,3-tetrasubstituted cyclobutanes enabled by cycloaddition of bicyclo[1.1.0]butanes. Meng Wang, Yingchao Huang, Chunyu Li, and Ping Lu*. Org. Chem. Front., 2022, 9, 2149–2153. Total Synthesis of (+)-Kingianin A by Enantioselective Cycloaddition of Strained Cyclobutenone Jie Zhanga, Peng Yanb,ZhichaoWangb, Jinbo Zhao*a, Qin Chen*b, Ping Lu*b Synthesis 2022, 54, 1977–1982. Dancing on Ropes Enantioselective Functionalization of Preformed Four Membered Carbocycles. Jun Chen, Qiang Zhou, Huayi Fang,* and Ping Lu*Chin. J. Chem. 2022, 40, 1346–1358. Synthesis of Dibenzo[a,e]cyclooctene-5,11(6H,12H)-diones via the Elusive Benzocyclobutenone Anion. Yingchao Huang, Jun Chen, Yu Liu*, and Ping Lu*Synthesis 2021, 53, 4477–4483. Enantioselective Synthesis of Indanes with a Quaternary Stereocenter via Diastereoselective C(sp3)−H Functionalization. Jun Chen, Zhan Shi, and Ping Lu*. Org. Lett. 2021, 23, 7359−7363. 3-(Methoxycarbonyl)Cyclobutenone as a Reactive Dienophile in Enantioselective Diels–Alder Reactions Catalyzed by Chiral Oxazaborolidinium Ions. Peng Yan, Changxu Zhong, Jie Zhang, Yu Liu, Huayi Fang, and Ping Lu*Angew. Chem. Int. Ed. 2021, 60, 4609–4613. Enantioselective Functionalization of Prochiral Cyclobutanones and Cyclobutenones. Meng Wang, Changxu Zhong, and Ping Lu*Synlett, 2021, 32, 1253–1259. Catalytic enantioselective synthesis of benzocyclobutenols and cyclobutanols via a sequential reduction/C–H functionalization. Jun Chen, Zhan Shi, Chunyu Li. and Ping Lu*Chem. Sci. 2021, 12, 10598-10604。 Chiral lithium amide mediated desymmetrization of 3-substituted cyclobutanone. Changxu Zhong, Shaowei Wang, and Ping Lu*. Org. Chem. Front., 2021, 8, 2977–2980. Controllable Skeleton Rearrangement of 3‐Substituted Cyclobutanones under Basic Conditions. Peng Yan, Qiang Zhou, Jun Chen, and Ping Lu*Chin. J. Chem. 2020, 38, 1103–1106. Enantioselective Synthesis of 3-Substituted Cyclobutenes by Catalytic Conjugate Addition/Trapping Strategies. Changxu Zhong+, Yingchao Huang+, Haocheng Zhang, Qiang Zhou, Yu Liu, and Ping Lu*,Angew. Chem. Int. Ed. 2020, 59, 2750–2754. Enantioselective Desymmetrization of Cyclobutanones Enabled by Synergistic Palladium/Enamine Catalysis. Meng Wang, Jun Chen, Zongjia Chen, Changxu Zhong, and Ping Lu*Angew. Chem. Int. Ed. 2018, 57, 2707–2711. 1‐Hydroxymethylbenzotriazole. Meng Wang, Ping Lu, and Armen Zakarian e-EROS (Encyclopedia of Reagents for Organic Synthesis), 2018, March. Recent Advances in Cooperative Catalysis of Chiral Lewis Base and Transition Metal Catalyst. Qiang, Zhou, and Ping Lu*Acta Chim. Sinica 2018, 76, 825-830. (invited article for issue: Asymmetric Organocatalysis Combined with Metal Catalysis) Catalytic approaches to assemble cyclobutane motifs in natural product synthesis. Meng Wang, and Ping Lu*. Org. Chem. Front. 2018, 5, 254–259. Controllable Skeleton Rearrangement of 3‐Substituted Cyclobutanones under Basic Conditions. Peng Yan, Qiang Zhou, Jun Chen, and Ping Lu* Chin. J. Chem. 2020, 38, 1103–1106. Enantioselective Synthesis of 3-Substituted Cyclobutenes by Catalytic Conjugate Addition/Trapping Strategies. Changxu Zhong+, Yingchao Huang+, Haocheng Zhang, Qiang Zhou, Yu Liu, and Ping Lu*, Angew. Chem. Int. Ed. 2020, 59, 2750–2754. Enantioselective Desymmetrization of Cyclobutanones Enabled by Synergistic Palladium/Enamine Catalysis. Meng Wang, Jun Chen, Zongjia Chen, Changxu Zhong, and Ping Lu* Angew. Chem. Int. Ed. 2018, 57, 2707–2711. 1‐Hydroxymethylbenzotriazole. Meng Wang, Ping Lu, and Armen Zakarian. e-EROS (Encyclopedia of Reagents for Organic Synthesis), 2018, March. Recent Advances in Cooperative Catalysis of Chiral Lewis Base and Transition Metal Catalyst. Qiang, Zhou, and Ping Lu* Acta Chim. Sinica 2018, 76, 825-830. Catalytic approaches to assemble cyclobutane motifs in natural product synthesis. Meng Wang, and Ping Lu*. Org. Chem. Front. 2018, 5, 254–259.