个人简介

B.Sc. (Hon) in Chemistry, King’s College, University of London, 1985 Ph.D. in Organic Chemistry, University of Illinois at Chicago, 1991 Postdoctoral Research Fellow, Brandeis University, Graduate Department of Biochemistry, 1990-93 Membership Committee, The Protein Society, 2008-present Member, Governing Council, American Society of Biochemistry and Molecular Biology (ASBMB), 2007-present Founding Member, Council for Systems Biology in Boston (CSB2), 2007-present Advisory Board Member, Institute for Chemical Biology and Drug Discovery, SUNY Stony Brook (2004-present) Co-Chair, 2002 Gordon Research Conference on Bioorganic Chemistry

研究领域

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Biological Chemistry

The Whitty Group studies protein-protein and protein-ligand recognition, with an emphasis on how binding energy from these intermolecular interactions can be utilized to achieve biological function or inhibition. We apply this research in two distinct areas: (i) developing a quantitative, mechanistic understanding of the activation and signaling of growth factor receptors, and (ii) advancing our ability to discover drugs that inhibit protein-protein interactions.