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一、功能化合物的合成与工艺 二、生物医用材料及其制备新技术 三、药用新剂型与制备新技术

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1、Jiaxing Hu, Qin Hua-Li, Xu Wengang, Li Junli, Zhang Fanglin, Zheng Hua. TfOH-catalyzed synthesis of 3-aryl isoindolinones via a tandem reaction [J]. Chem. Commun., 2014, 50(99): 15780-15783. 2、D. Li, Lu B., Huang Z., Xu P., Zheng H., Yin Y., Xu H., Liu X., Chen L., Lou Y., Zhang X., Xiong F. A novel melphalan polymeric prodrug: preparation and property study [J].Carbohydr Polym, 2014, 111:928-935. 3、Chuxiang Sun, Shu Ke, Wang Wei, Ye Zhao, Liu Ting, Gao Yuxiang, Zheng Hua, He Guanghua, Yin Yihua. Encapsulation and controlled release of hydrophilic pesticide in shell cross-linked nanocapsules containing aqueous core [J]. Int. J. Pharm., 2014, 463(1): 108-114. 4、Cheng Gao, Liu Ting, Dang Yinghua, Yu Zhiyan, Wang Wei, Guo Jingjing, Zhang Xueqiong, He Guanghua, Zheng Hua, Yin Yihua, Kong Xiangqi. pH/redox responsive core cross-linked nanoparticles from thiolated carboxymethyl chitosan for in vitro release study of methotrexate [J]. Carbohydrate Polymers, 2014, 111: 964-970. 5、Bo Lu, Huang Dan, Zheng Hua, Huang Zhijun, Xu Peihu, Xu Haixing, Yin Yihua, Liu Xia, Li Dan, Zhang Xueqiong. Preparation, characterization, and in vitro efficacy of O-carboxymethyl chitosan conjugate of melphalan [J]. Carbohydr. Polym., 2013, 98(1): 36-42. 6、Yihua Yin, Sha Xu, Dan Chang,Hua Zheng, Junli Li, Xiaoping Liu, Peihu Xu, Fuliang Xiong. One-pot synthesis of biopolymeric hollow nanospheres by photocrosslinking. Chemical Communications, 2010, 46(43): 8222-8224. 7、Xiaoyu Gong, Yihua Yin, Zhijun Huang, Bo Lu, Peihu Xu, Hua Zheng, Fuliang Xiong. Preparation, characterization, and in vitro release study of a glutathione-dependent polymeric prodrug cis-3-(9H-purin-6-ylthio)-acrylic acid-graft-carboxymethyl chitosan.International Journal of Pharmaceutics,2012,436: 240-247. 8、Bo Lu, Xu Liu, Zhijun Huang, Haixing Xu, Peihu Xu, Yiting Wang, Hua Zheng, Yihua Yin, Xianzheng Zhang, Renxi Zhuo. Synthesis of diamine maleyl chitosans, and in vitro transfection studies. Carbohydrate Polymers, 2012, 87, 1453-1459. 9、He Guanghua, Wang Zi, Zheng Hua, Yin Yihua, Xiong Xiong. Preparation, characterization and properties of aminoethyl chitin hydrogels. Carbohydrate Polymers, 2012, 90, 1614-1619. 10、Houwei Tu, Yi Qu, Xiaohua Hu, Yihua Yin, Hua Zheng, Peihu Xu, Fuliang Xiong. Study of the sigmoidal swelling kinetics of carboxymethylchitosan-g- poly(acrylic acid) hydrogels intended for colon-specific drug delivery. Carbohydrate Polymers, 2010,82:440-445. 11、Yihua Yin, Xianglan Lv, Houwei Tu, Sha Xu, Hua Zheng. Preparation and swelling kinetics of Ph-sensitive photocrosslinked hydrogel based on carboxymethyl chitosan. Journal.of Polymer Research,2010, 17: 471-479. 12、Lu B, Wu DQ, Zheng H, Quan CY, Zhang XZ, Zhuo RX. Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer. Molecular BioSystems,2010, 6, 2529-2538. 13、 Hua Zheng, Yan Rao, Yihua Yin, Xiong Xiong, Peihu Xu, Bo Lu. Preparation, characterization, and in vitro drug release behavior of 6-mercaptopurine carboxymethyl chitosan. Carbohydrate Polymers, 2011, 83:1952-1958. 14、)Hua Zheng,Xueqiong Zhang, Fuliang Xiong, Zhongjia Zhu, Bo Lu, Yihua Yin, Peihu Xu, Yumin Du. Preparation, characterization, and tissue distribution in mice of lactosaminated carboxymethyl chitosan nanoparticles. Carbohydrate Polymers, 2011, 83:1139-1145. 15、Hua Zheng, Xueqiong Zhang, Yihua Yin, Fuliang Xiong, Xiaoyu Gong, Zhongjia Zhu, Bo Lu, Peihu Xu. In vitro characterization, and in vivo studies of crosslinked lactosaminated carboxymethyl chitosan nanoparticles. Carbohydrate Polymers, 2011, 84:1048-1053. 16、Ying Yi, Sha Xu, Haikuan Sun, Dan Chang, Yihua Yin, Hua Zheng, Haixing Xu, Yiceng Lou. Gelation of photocrosslinkable carboxymethyl chitosan and its application in controlled release of pesticide. Carbohydrate Polymers,2011,86:1007-1013. 17、Bo Lu, Xu Liu, Zhijun Huang, Haixing Xu, Peihu Xu, Yiting Wang, Hua Zheng, Yihua Yin, Xianzheng Zhang, Penxi Zhuo. Synthesis of diamine maleyl chitasans, and in vitro transfection studies. Carbohydrate Polymers, 2012,87:1453-1459. 18、Dan Chang, Jing Lei, Huiran Cui, Na Lu, Yanjuan Sun, Xiaohua Zhang, Cheng Gao, Hua Zheng, Yihua Yin.Disulfide cross-linked nanospheres from sodium alginate derivative for inflammatory bowel disease: Preparation, characterization, and in vitro drug release behavior.Carbohydrate Polymers, 2012,88:663-669. 19、Ling Kai, Zheng Fei, Li Junli, Tang Rupei, Huang Jin, Xu Yongmei, Zheng Hua, Chen Jinghua. Effects of substitution degree of photoreactive groups on the properties of UV-fabricated chitosan scaffold. Journal of Biomedical Materials Research Part A, 2008, 87(1): 52-61. 20、Xu Yong Mei, Zhan Chang You, Fan Li Hong, Wang Le, Zheng Hua. Preparation of dual crosslinked alginate-chitosan blend gel beads and in vitro controlled release in oral site-specific drug delivery system. International Journal of Pharmaceutics. 2007, 336 (2): 329-337.

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