研究领域
探寻候选基因与疾病之间的易感性，阐述候选基因在疾病的发生过程中的作用机制，以及从表观遗传学的角度来探究癌症发生发展过程中，小RNA分子(microRNA)和DNA甲基化(DNA methylation)等表观遗传学手段在其中的作用。
近期论文
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1. Tang L, Wan P, Wang Y, Pan J, Wang Y, Chen B. Genetic association and interaction between the IRF5 and TYK2 genes and systemic lupus erythematosus in the Han Chinese population.Inflamm Res. 2015; 64(10):817-24. (Corresponding author; IF=2.347)
2. Lu Li*, Bi-Feng Chen* and Wai-Yee Chan. An Epigenetic Regulator: Methyl-CpG-Binding Domain Protein 1 (MBD1). Int J Mol Sci. 2015 Mar; 16(3): 5125–5140. (*Co-first Author; IF=2.862)
3.Wang Y, Tang L, Pan J, Li J, Zhang Q, Chen B. The recessive model of MRP2 G1249A polymorphism decrease the risk of drug-resistant in Asian Epilepsy: a systematic review and meta-analysis. Epilepsy Res. 2015;112:56-63. (Corresponding author; IF=2.015)
4. Chen BF, Suen YK, Gu S, Li L, Chan WY. A miR-199a/miR-214 Self-Regulatory Network via PSMD10, TP53 and DNMT1 in Testicular Germ Cell Tumor. Scientific Reports. 2014; 4:6413. (IF=5.078）
5. Bi-Feng Chenand Wai-Yee Chan: The de novo DNA methyltransferase DNMT3A in development and cancer. Epigenetics: official journal of the DNA Methylation Society. 2014; 9 (5): 669-77. (IF=5.108）
6. Chen BF, Gu S, Suen YK, Li L, Chan WY.MicroRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer. Epigenetics: official journal of the DNA Methylation Society 2014; 9(1):119-128. (IF=5.108）
7.Liang Tang, Yan Wang,Bifeng Chen: A variant within intron 1 of PTPN22 gene decreases the geneticsusceptibility of Ankylosing Spondylitis in central south Chinese Han population. Scand J Rheumatol. 2014; 43(5):380-384. (Corresponding author; IF=2.607)
8.Liang Tang*, Bifeng Chen*, Bo Ma, Shengjie Nie: The Association between IRF5 polymorphisms and autoimmune diseases: a meta-analysis. Genet Mol Res. 2014;16;13(2):4473-85. (*Co-first Author; IF=0.850)
9.Liang Tang, Honggang Lin, Bifeng Chen: Association of IL4 promoter polymorphisms with asthma: A meta-analysis. Genet Mol Res. 2014; 13(1):1383-1394. (Corresponding author; IF=0.850)
10. Bifeng Chen, Tao Gu, Bo Ma, Guoqing Zheng, Bingxiong Ke, Xiufeng Zhang, Lirui Zhang, Yuanyuan Wang, Liping Hu, Yang Chen, Jianbo Qiu, Shengjie Nie: The CRHR1 gene contributes to genetic susceptibility of aggressive behavior towards others in Chinese Southwest Han population. Journal of molecular neuroscience. 2013; 52(4):481-486. (IF=2.757)
11.Wen LI, Bi-feng CHEN: Aberrant DNA Methylation in Human Cancers. J Huazhong Univ Sci Technol [Med Sci]. 2013; 33(6): 786-792. (Corresponding author; IF= 0.779)
12. Chen B, Nie S, Yue Z, Shou W, Xiao C. Haplotype-based case-control study of the human CYP11B2 gene and essential hypertension in Yi and Hani minorities of China. Biochem Genet. 2011; 49:122-37. (IF=0.822)
13. Chen B, Nie S, Luo S, Zhang W, Xiao C. Association of the human CYP11B2 gene and essential hypertension in southwest Han Chinese population: a haplotype-based case-control study. Clin Exp Hypertens. 2011; 33:106-12. (IF=1.456)
14. 唐亮，王燕，陈碧峰。人Toll样受体9基因启动子区的生物信息学分析。《生物技术通讯》，2014年第25卷第2期210-212页。（通讯作者）
15. Ji-hang Yuan, Fu Yang, Bi-feng Chen, Zhi Lu, Xi-song Huo, Wei-ping Zhou, Fang Wang, Shu-han Sun: The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma. Hepatology. 2011; 54(6):2025-35. (IF=12.003)
16.Jihang Yuan, Yubao Wei, Bifeng Chen, Kai Huang, Ying He, Weiping Huang, Kaihui Wang, Sunhan: An investigation of the α2A-adrenrgic receptor gene and seasickness in chinese naval men. Journal of BTHA (British Travel Health Association) 01/2011. (Uncited by SCI)
17. Yang Yanmei, Gu Tao, Zeng Yubao, Xiao Chunjie,Chen Bifeng, Luo Shi, Xu Bingying, Jing Qiang, Zhuang Qinyong, Zhang Wen, Luo Shengjun, Nie Shengjie: Genetic polymorphism of 11 Y-chromosomal STR loci in Yunnan Han Chinese. Forensic science international. Genetics. 2010; 4(2):e67-9. (IF=3.861)
18. Sheng-jie Nie, Tang Wen-ru, Chen Bi-feng, Li Jin, Zhang Wen, Luo Sheng-jun, Li Wei-wei, Yu Hai-jing, Xiao Chun-jie: Haplotype-based case-control study of the human AGTR1 gene and essential hypertension in Han Chinese subjects. Clinical biochemistry. 2009; 43(3):253-8. (IF=2.45)
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