李子元 - 四川大学 - 化学工程学院

研究领域

1）药物研发中的有机化学新方法，特别是杂环的构建及官能团化新方法； 2）天然产物全合成和基于天然活性分子的新药研发； 3）新型药物载体材料的研究与开发。

近期论文

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Ziyuan Li, Xiaoqiang Huang, Feng Chen, Chun Zhang, Xiaoyang Wang, Ning Jiao*. Cu-Catalyzed Concise Synthesis of Pyridines and 2-(1H)-Pyridones from Acetaldehydes and Simple Nitrogen Donors [J]. Org. Lett. 2015, 17, 584-587. (IF = 6.324) Ziyuan Li, Haipin Zhou, Xiaoming Wu*, Hequan Yao*. Advances in Chemical Synthesis of Structurally Modified Bioactive RNAs [J]. Curr. Med. Chem. 2013, 20, 3641-3654. (IF = 3.72) Ziyuan Li, Haipin Zhou, Jinyi Xu, Xiaoming Wu, Hequan Yao*. Aryl-aryl Coupling via Palladium-catalyzed C-P/C-H Bond Cleavage [J]. Tetrahedron 2013, 69, 3281-3286. (IF = 2.82) Guangling Zhang, Ziyuan Li, Yue Huang, Jinyi Xu, Xiaoming Wu, Hequan Yao*. Direct C3-alkenylation of Pyridin-4(1H)-one via Oxidative Heck Coupling [J]. Tetrahedron 2013, 69, 1115-1119. (IF = 2.82) Ziyuan Li, Ling Ma, Lingyi Kong, Jinyi Xu, Xiaoming Wu, Hequan Yao*. Pd(II)-catalyzed Direct C5-arylation of Azole-4-carboxylates through Double C–H Bond Cleavage [J]. Chem. Commun. 2012, 48, 3763-3765. (IF = 6.378) Lei Zhao, Ziyuan Li, Lin Chang, Lingyi Kong, Hequan Yao*, Xiaoming Wu*. Efficient Construction of Fused Indolines with a 2-Quaternary Center via an Intramolecular Heck Reaction with a Low Catalyst Loading [J]. Org. Lett. 2012, 14, 2066-2069. (IF = 6.142) Lijun Ni, Ziyuan Li, Fan Wu, Jinyi Xu, Xiaoming Wu, Lingyi Kong, Hequan Yao*. Concise Total Syntheses of Marinoquinolines A–C [J]. Tetrahedron Lett. 2012, 53, 1271-1274. (IF = 2.40) Ziyuan Li, Yiyun Wang, Yue Huang, Changhua Tang, Jinyi Xu, Xiaoming Wu*, Hequan Yao*. Efficient Palladium(II)-catalyzed Homocoupling of Thiazole-4-carboxylic or Oxazole-4- Carboxylic Derivatives [J]. Tetrahedron 2011, 67, 5550-5555. (IF = 3.03) Ziyuan Li, Ling Ma, Changhua Tang, Jinyi Xu, Xiaoming Wu, Hequan Yao*. Palladium(II)-catalyzed Oxidative Heck Coupling of Thiazole-4-carboxylates [J]. Tetrahedron Lett. 2011, 52, 5643-5647. (IF = 2.68) Changhua Tang, Ziyuan Li, Yiyun Wang, Xiaoming Wu*, Hequan Yao*. First Total Synthesis of Tenuifolin via PIFA Mediated Oxidative Biaryl Coupling [J]. Tetrahedron Lett. 2011, 52, 3275-3278. (IF = 2.68) Yiyun Wang, Ziyuan Li, Yue Huang, Changhua Tang, Xiaoming Wu, Jinyi Xu*, Hequan Yao*. Copper(II)-catalyzed Oxidation of 4-Carboxythiazolines and 4-Carboxyoxazolines to 4-Carboxythiazoles and 4-Carboxyoxazoles [J]. Tetrahedron 2011, 67, 7406-7411. (IF = 3.03) Ziyuan Li, Yinyu Wang, Changhua Tang, Jinyi Xu, Xiaoming Wu*, Hequan Yao*. Synthesis of 3-Benzoyl Acrylates/Acrylamides via Dehydrogenation of 3-Benzoyl Propionates/ Propionamides Using IBX/p-TsOH [J]. Chinese J. Chem. 2010, 28, 1301-1305. (IF = 1.578)