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主要研究方向为:复杂网络、数据挖掘、医学本体论与中医信息学等。发表论文100余篇,其中SCI论文20余篇,EI/ISTP检索论文20余篇。部分论文如下。
[1]. Ma W, Zhang L, Zeng P, Huang C, Li J, Geng B, Yang J, Kong W, Zhou X, Cui Q, An analysis of human microbe-disease associations. Briefings in Bioinformatics. Feb 2016(SCI IF=9.62).
[2]. Li Y, Zhou X*, Zhang R, Wang Y, Peng Y, Hu J, Xie Q, Xue Y, Xu L, Liu X, Liu B, Detection of Herb-Symptom Associations from Traditional Chinese Medicine Clinical Data. Evidence-based Complementary and Alternative medicine. http://dx.doi.org/10.1155/2015/270450. 2015 (SCI, IF=2.176).
[3]. Xuezhong Zhou*, Yubing Li, Yonghong Peng, Jingqing Hu, Runshuang Zhang, Liyun He, Yinghui Wang, Lijie Jiang, Shiyan Yan, Peng Li, Qi Xie, Baoyan Liu*, Clinical Phenotype Network: the underlying mechanism for personalized diagnosis and treatment of traditional Chinese medicine. Frontier of medicine, 2014.8. DOI:10.1007/s11684-014-0349-8(SCI).
[4]. 孟志昌,周雪忠*,雷蕾*,刘保延,张润顺,王映辉,谢琪. 基于计算的中药药物靶点预测研究探讨与实验分析.世界科学技术-中医药现代化. 2014(11), pp 15-23.
[5]. 杨丽, 周雪忠,毕斓馨,张润顺,王映辉,刘保延,谢琪,基于案例推理的中医临床诊疗决策支持系统. 世界科学技术-中医药现代化.2014;16(3):474-480.
[6]. Zhou X*, Menche J, Barabasi A-L, Sharma A, Human symptoms disease network. Nature communications. 01/2014;5:4212 (SCI, IF=10.742).
[7]. Li X, Zhou X*, Peng Y*, Liu B, Zhang R, Hu J, Yu J, Jia CY, Sun CK, Network based integrated analysis of phenotype-genotype data for prioritization of candidate symptom genes. Biomed Research International. 2014.6 http://dx.doi.org/10.1155/2014/435853.(SCI, IF=2.88).
[8]. Yukinori Okada、Di Wu、Gosia Trynka、Towfique Raj、Chikashi Terao、 Katsunori Ikari、...、Xuezhong Zhou、..., Robert M Plenge, Genetics of rheumatoid arthritis contributes to biology and drug discovery, Nature, doi:10.1038/nature12873,2013(SCI IF=38.579).
[9]. Gang Li、Dorothée Diogo、Di Wu、Jim Spoonamore、Vlado Dancik、 Lude Franke、Fina Kurreeman、 Elizabeth J Rossin、 Grant Duclos、Cathy Hartland、 Xuezhong Zhou、...、 Robert M Plenge,Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway, PLoS genetics,2013;9(5):1-12(SCI IF=8.517).
[10]. Yubing Li、Xuezhong Zhou*、Runshun Zhang、Yinghui Wang、 Jingqing Hu、Qi Xie、Baoyan Liu,Complex Network Approach for Analyzing TCM Clinical Herb-Symptom Relationships, Bioinformatics and Biomedicine (BIBM), 2013 IEEE International Conference on,2013.12.18-21,Shanghai, 116-117.
[11]. Xing Li, Xuezhong Zhou, Yonghong Peng, Runshun Zhang, Jingqing Hu, Jian Yu, Baoyan Liu, Integrating Phenotype-genotype Data for Prioritization of Candidate Symptom Genes. Bioinformatics and Biomedicine (BIBM), 2013 IEEE International Conference on,2013.12.18-21,Shanghai, 279-280 页.
[12]. Lijie Jiang, Baoyan Liu, Qi Xie, Shuhong Yang, Liyun He, Runshun Zhang, Shiyan Yan, Xuezhong Zhou, Jia Liu, Investigation into the Influence of Physician for Treatment Based on Syndrome Differentiation, Evidence-Based Complementary and Alternative Medicine,2013(1),1-16,2013(SCI,IF=2.175).
[13]. Yan Feng, Yu Qiu, Xuezhong Zhou, Yixin Wang, Hao Xu, Baoyan Liu, Optimizing Prescription of Chinese Herbal Medicine for Unstable Angina Based on Partially Observable Markov Decision Process, Evidence-Based Complementary and Alternative Medicine,2013(1),1-6.
[14]. Qi Feng, Xuezhong Zhou*, Houkuan Huang, Xiaoping Zhang, Runshun Zhang, Modelling traditional Chinese medicine therapy planning with POMDP, International Journal of Functional Informatics and Personalised Medicine. 2013;4(2):145-166.
[15]. 张磊、周雪忠、于剑、王义国、张启明,592 例慢性乙型病毒性肝炎湿热证有效病例用药规律研究,中医杂志,第 54 卷,第 8 期,668-672 页, 2013
[16]. 周霞继、王映辉、刘保延、张润顺、周雪忠、张红、樊俊芝、郭 玉峰、宋观礼,中医药(临床)信息学学科概况,中国数字医学,第 8 卷,第 5 期,55-58 页,2013.
[17]. 王思成、刘保延、熊宁宁、谢琪、张润顺、周雪忠、乔治,真实世界临床研究伦理问题及策略探讨,中国中西医结合杂志 ,第 33 卷,第 4 期,437-442 页,2013.
[18]. Bi Lanxing, Zhou Xuezhong, Zhang Lei, Zhang Runshun, Multidimensional Analysis for Traditional Chinese Medicine Diagnosis and Treatment on Hepatitis Diseases. IEEE HealthCom 2012. pp.52-56.
[19]. Jiang Zaixing, Zhou Xuezhong, Yu Jian, Zhang Xiaoping, Using Link Topic Model to Analyze Traditional Chinese Medicine Clinical Symptom-Herb Regularities. IEEE HealthCom 2012. pp.15-18.
[20]. Pan Xishui, Zhou Xuezhong, Zhang runshun, Song hongmei, Enhanced Data Extraction, Transforming and Loading Processing for Traditional Chinese Medicine Clinical Data Warehouse. IEEE HealthCom 2012. 57-61.
[21]. 张润顺,周雪忠,王映辉,刘保延等。利用名中医诊疗信息采集及分析挖掘平台开展肿瘤中医诊疗经验研究的思路与实践。世界科学技术:中医药现代化. 2012;14(4):1817-1823.
[22]. 刘保延,周雪忠,张润顺,王映辉等,医疗与临床科研信息共享系统中医电子病历系统信息基本要求.中国数字医学. 2012;7(10):10.3969/j.issn.1673-7571.2012.10.016
[23]. Baoyan Liu, Xuezhong Zhou, Yinhui Wang, Jingqing Hu, Liyun He, Runshun Zhang, Shibo Chen, Yufeng Guo, Data processing and analysis in real-world traditional Chinese medicine clinical data: challenges and approaches. Statistics in medicine, 2012;31:653-660(SCI,IF=2.044).
[24]. Poon S, Fan K, Poon J, Loy C, Chan K, Zhou X, Zhang R, Wang Y, Xie J, Liu B, Kwan P, Gao J, Sze D, Analysis of Herbal Formation of TCM:A Case on Infertility. BIBM ITCM workshop 2011, USA, pp.868-872.
[25]. Poon J, Yin D, Poon S, Zhou X, Zhang R, Liu B, Sze D, Co-evolutionary Genetic Algorithm in Symptom-Herb Relationship Discovery. BIBM ITCM workshop 2011, USA, pp.890-896.
[26]. Tao Chen, Xue-zhong Zhou, Run-shun Zhang and Lian-wen Zhang, Discovery of regularities in the use of herbs in Chinese medicine prescriptions. Chin J Integr Med. DOI: 10.1007/s11655-011-0860-6 (SCIE).
[27]. Ninglin Du, Xuezhong Zhou, Runshun Zhang, Caiyan Jia, Jian Yu, Baoyan Liu, Multiscale backbone based network comparison algorithm for effective herbal interaction analysis. In Proceedings of BMEI 2011, Shanghai, China, pp.1774-1779.
[28]. Zhou Xuezhong, Zhang Runshun, Shah Jatin, Rajgor Dimple, Wang Yinghui, Pietrobon Ricardo, Liu Baoyan, Chen Jie, Zhu Jiangui, and Gao Ronglin, Patterns of Herbal Combination for the Treatment of Insomnia Commonly Employed by Highly Experienced Chinese Medicine Physicians. Chin J Integr Med. 2011 Sep;17(9):655-62. (SCIE).
[29]. Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He and Xuezhong Zhou, Thinking and practice of accelerating transformation of traditional Chinese medicine from experience medicine to evidence-based medicine. Frontiers of Medicine.2011;5(2):163-170.
[30]. Simon K. Poon, Josiah Poon, Martin McGrane, Xuezhong Zhou, Paul Kwan, Runshun Zhang, Baoyan Liu, Junbin Gao, Clement Loy, Kelvin Chan, Daniel Sze, A Novel Approach in Discovering Significant Interactions from TCM Patient Prescription Data. International Journal of Data Mining and Bioinformatics. 2011 Vol. 5, No.4 pp. 353 - 368 (SCI).
[31]. 冯奇, 周雪忠, 黄厚宽, 张小平, SHP-VI:一种基于最短哈密顿通路的POMDP值迭代算法. 计算机研究与发展. 2011;48(12):2343-2351.
[32]. 王映辉,周雪忠,张润顺,刘保延,姚乃礼,薛燕星等,利用复杂网络与点式互信息法分析挖掘名老中医用药经验研究。中国数字医学。2011;6(4):76-80.
[33]. Xiaoping Zhang, Xuezhong Zhou, Houkuan Huang, Qi Feng, Shibo Chen, Baoyan Liu, Topic Model for Traditional Chinese Medicine Diagnosis and Prescription Regularities Analysis: Case on Diabetes. Chinese Journal of Integrative Medicine. 2011.4;17(4):307-313 (SCIE).
[34]. Qi Feng, Xuezhong Zhou, Houkuang Huang, Yin Zhang, A MDP solution for Traditional Chinese Medicine Treatment Planning. BMEI 2010. 2010.10;2250-2254.
[35]. Xiaoping Zhang, Xuezhong Zhou, Houkuang Huang, Shibo Chen, A Hierarchical Symptom-Herb Topic Model for Analyzing Traditional Chinese Medicine Clinical Diabetic Data. BMEI 2010. 2010.10;2246-2249.
[36]. Martin McGrane, Simon Poon, Josiah Poon, Xuezhong Zhou, et al., Analysis of Synergistic and Antagonistic Effects of TCM: Cases on Diabetes. BIBM ITCM 2010. 2010.12;620-625.
[37]. Josiah Poon, Simon Poon, Xuezhong Zhou, Runshun Zhang, et al., Studying Herb-Herb Interation for Insomnia through the theory of complementarities. BIBM ITCM 2010, HongKong.2010.12;722-727.
[38]. Ping Li, Xuezhong Zhou, Ronglin Gao and Sa Wu, Empirical Study on Treatment of Coronary Heart Disease with Famous Doctor's method of regulating spleen and stomach based on simplified point-wise mutual information. BIBM ITCM 2010, HongKong.2010.12;617-620.
[39]. 谢琪,刘保延,李鲲,文天才,周雪忠,张润顺, 论中医药临床数据的科学价值. 国际中医中药杂志. 2010.9;32(5):455-456.
[40]. Xuezhong Zhou, Yonghong Peng, Baoyan Liu. Text mining for traditional Chinese medical knowledge discovery: a survey. Journal of Biomedical Informatics. Volume 43, Issue 4, August 2010, Pages 650-660 (SCI).
[41]. Xuezhong Zhou, Josiah Poon, Runshun Zhang, Simon Poon, et al, Novel Two-Stage Analytic Approach in Extraction of Strong Herb-Herb Interactions in TCM Clinical Treatment of Insomnia. Medical Biometrics 2010, Hongkong, LNCS 2010, Volume 6165/2010, 258-267.
[42]. Xuezhong Zhou, Shibo Chen, Baoyan Liu, Runsun Zhang, Yinghui Wang, Ping Li, et al. Development of Traditional Chinese Medicine Clinical Data Warehouse for Medical Knowledge Discovery and Decision Support. Artificial Intelligence in medicine. 2010 February-March;48 (2-3):139-152 (SCI).
[43]. 张小平, 周雪忠, 黄厚宽, 冯奇, 陈世波. 基于词相似性与CRP的主题模型, 人工智能与模式识别, 2010.2;23(1):72-76 (EI).
[44]. 白宇宁,张润顺,白兆芝,姚乃礼,白震宁,寇永锋,王健,胡明丽,王洪艳,周雪忠,中医小肠病治法及用药规律的临床研究,中国中医药信息杂志.2010,17(8).-88-90.
[45]. 庄力, 周雪忠, 贾彩燕, 于剑, 张润顺, 王映辉, 基于Biclustering的中医药症关系分析, 计算机工程.2010,36(11):241-243.
[46]. 刘红, 涂强, 周雪忠, 赵东升, 亢力, 中药方剂药物配伍网络构建程序的并行化实现及其应用. 中国数字医学.2010(5):39-41.
[47]. 张润顺, 周雪忠, 姚乃礼, 王映辉, 基于临床数据分析的肝脾不调证候诊断标准临床适用性研究. 世界科学技术:中医药现代化.2010(2):181-184.
[48]. 吴荣, 聂晓燕, 王阶, 周雪忠, 基于贝叶斯网络的名老中医治疗冠心病辨证规律研究. 中国中医药信息杂志.2010,17(5):98-99.
[49]. 张小平, 周雪忠, 黄厚宽, 冯奇, 陈世波, 焦宏官,一种改进的LDA主题模型. 北京交通大学学报:自然科学版.2010(2):111-114.
[50]. 高铸烨, 张京春, 徐浩, 史大卓, 付长庚, 曲丹, 周雪忠, 用复杂网络挖掘分析冠心病证候-治法-中药关系. 中西医结合学报.2010,8(3):238-243.
[51]. 张润顺, 周雪忠, 姚乃礼, 王映辉, 基于关联规则挖掘肝脾不调证中药配伍规律研究. 中国中医药信息杂志.2010(2): 97-99.
[52]. 周霞继, 刘保延, 郭玉峰, 闫秀峰, 张润顺, 周雪忠,中医临床术语集在临床科研信息采集系统中的应用. 中国数字医学. 2010, 5(10):60-62.
[53]. 张润顺,周雪忠,姚乃礼,王映辉,基于复杂网络分析的肝脾不调证的配伍特点研究。世界科学技术-中医药现代化。2010;12(6):882-887
[54]. Xuezhong Zhou, Baoyan Liu, Network analysis system for traditional Chinese medicine clinical data. BMEI 2009, Tianjin, Vol 3: 1621-1625.
[55]. Qi Feng, Xuezhong Zhou, Houkuang Huang, Xiaoping Zhang, An Uncertainty-based Belief Selection Method for POMDP Value Iteration. ECSQARU 2009, 1-3 July 2009, Verona (Italy), 841-849.
[56]. 王映辉, 张润顺, 周雪忠, 刘保延, 薛燕星, 李平, 李文泉, 李格, 吴力群, 冀晓华, 宋军, 名老中医经验共性规律及个性差异比较研究. 世界科学技术:中医药现代化.2009(6):793-799.
[57]. 刘杰, 林洪生, 侯炜, 李道睿, 周雪忠, 利用数据挖掘方法对肺癌中医药治疗特点的初步研究. 世界科学技术:中医药现代化.2009(5):753-757.
[58]. 陈世波, 刘保延, 倪青, 周雪忠, 何丽云, 2型糖尿病“症”分类的影响因素及框架研究. 中国中医药信息杂志.2009,16(6):4-5.
[59]. 冯奇,周雪忠,黄厚宽,张小平, POMDP基于点的值迭代算法中一种信念选择方法. 北京交通大学学报:自然科学版.2009,33(5):77-80.
[60]. Xuezhong Zhou, Baoyan Liu, Traditional Chinese medicine clinical data mining: experiences and issues. Advances and Issues in Biomedical Data Mining Workshop of PAKDD 2009, Thailand, Apri 27-30 2009.
[61]. Xiaoping Zhang, Xuezhong Zhou, Houkuang Huang, Shibo Chen, Qi Feng, Multi-Relational Topic Model for TCM Clinical Knowledge Discovery. Advances and Issues in Biomedical Data Mining Workshop of PAKDD 2009, Thailand, Apri 27-30 2009.
[62]. Xuezhong Zhou, Runshun Zhang, Yinghui Wang, Ping Li, Baoyan Liu, Network analysis for core herbal combination knowledge discovery from clinical Chinese medical formulae. DBTA 2009. 2009年4月25-26.
[63]. Xuezhong Zhou, Shibo Chen, Baoyan Liu, Runsun Zhang, Yinghui Wang, Xiaoping Zhang, Extraction of hierarchical core structures from traditional Chinese medicine herb combination network. In proceedings of ICAI 2008. Beijing, China. 2008 Oct. Posts & Telecom press, pp.262-67.
[64]. Xuezhong Zhou, Shibo Chen, Baoyan Liu, Runsun Zhang, Yinghui Wang, Ping Li, Yufeng Guo, Building Clinical Data Warehouse for Traditional Chinese Medicine Knowledge Discovery. BMEI. 2008, vol 1, pp.615-620.
[65]. 周雪忠,刘保延,王映辉,张润顺,李平. 复方药物配伍的复杂网络方法研究. 中国中医药信息杂志.2008;15(11):98-100.
[66]. 李平,周雪忠. 基于无尺度网络模型的路志正教授核心经验方药初步探讨. 中国中医药信息杂志,2008;15(8):71-72.
[67]. 郭玉峰,刘保延,周雪忠. SNOMED CT 2007的顶级概念分类详解. 中华中医药学刊. 2008;26(9):1928-32.
[68]. 张润顺,王映辉,周雪忠,刘保延,姚乃礼,李平. 名老中医经验要素研究及智能挖掘平台功能设计. 世界科学技术-中医药现代化, 2008;10(1):45-52.
[69]. Xuezhong Zhou, Baoyan Liu, Zhaohui Wu, Yi Feng, Integrative mining of traditional Chinese medicine literature and MEDLINE for functional gene networks. Artificial Intelligence in Medicine, 2007,41, pp.87-104 (SCI/EI).
[70]. 周雪忠,刘保延,姚乃礼,陈世波,李平,王映辉,张润顺,中医临床数据仓库及挖掘分析平台的研究与应用探讨[J].世界科学与技术-中医药现代化。2007; 9(4):74-80.
[71]. 刘保延,周雪忠. 中医临床研究方法的思考与实践——系统生物学湿干研究模式与中医临床研究. 世界科学技术-中医药现代化, 2007;9(1):85-9.
[72]. Yi Feng, Zhaohui Wu, Xuezhong Zhou, Zhongmei Zhou., Knowledge discovery in traditional Chinese medicine: state of the art and perspectives. Artificial Intelligence in Medicine. 2006,Vol.38, pp.219-236 (SCI/EI).
[73]. Xuezhong Zhou, Baoyan Liu, Zhaohui Wu, Text Mining for clinical Chinese herbal medical knowledge discovery. ALT/DS-2005, Singapore, Lecture Notes in Artificial Intelligence (LNAI), 2005, Vol.3735, pp.366-368 (SCIE).
[74]. Xuezhong Zhou, Zhaohui Wu, Aining Yin, Lancheng Wu, Weiyu Fan, Ruen Zhang, Ontology development for unified traditional Chinese medical language system. Artificial Intelligence in Medicine, 2004, Vol 32, pp.15-27 (SCI/EI).
[75]. Zhaohui Wu, Xuezhong Zhou, Baoyan Liu, Junli Chen, Text mining for finding functional community of related genes using TCM knowledge. ECML/PKDD-2004, Italy, Pisa, Lecture Notes in Artificial Intelligence (LNAI). 2004, Vol.3202, pp.459-470 (SCIE).
[76]. Xuezhong Zhou, Zhaohui Wu: Distributional Character Clustering for Chinese Text Categorization. PRICAI 2004: 575-584 (SCIE).
[77]. Junli Chen, Xuezhong Zhou, Zhaohui Wu: A Multi-Label Chinese Text Categorization System Based on Boosting Algorithm. CIT 2004: 1153-1158 (SCIE)
[78]. 周雪忠,吴朝晖,刘保延,生物医学文献知识发现研究与展望。复杂系统与复杂性科学杂志,2004;1(3): 45-55.
[79]. 周雪忠,崔蒙,吴朝晖. 基于文本挖掘的中医学文献主题自动标引. 中国中医药信息杂志. 2003;10(1):71-74.
[80]. 周雪忠,吴朝晖,文本知识发现:基于信息抽取的文本挖掘。计算机科学,2003;30(1): 63-67.
专著/译著
Xuezhong Zhou、Baoyan Liu、Xiaoping Zhang、Qi Xie, Runshun Zhang、Yinghui Wang、Yonghong Peng,Data mining in real-world traditional Chinese medicine clinical data warehouse (Book chapter): Data Analytics for Traditional Chinese Medicine Research, edited by Josiah Poon and Simon K. Poon,Springer, 2014.