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个人简介

教育背景 1994.9-1997.6 天津大学化工工程与技术 博士研究生 1992.9-1994.6 天津大学化工工程与技术 硕士研究生 1987.9-1992.6 清华大学化学工程 学士 工作经历 1997-1999 北京化工大学化学工程与技术博士后流动站,博士后 1999-2003 北京化工大学化学工程学院,副教授, 教授 2003-2017 北京化工大学生命科学与技术学院,院长 2017-2019 北京化工大学人才引进办公室,主任 2019-至今 北京化工大学 规划与学科建设办公室,主任

研究领域

袁其朋教授是北京化工大学天然药物科学与工程学科的学术带头人,其研究主要集中于天然活性成分分离、生物合成及合成生物学等科学领域。围绕当前人民对健康的需求,聚焦于天然活性成分规模制备中的关键科学与技术问题,开展生物合成及分离领域的创新研究。有扎实的理论基础和丰富的实践经验,并且组建了一支综合素质良好的科研团队。在应用基础、技术创新及成果转化等方面成果突出,提升了国内植提行业的水平,发展了合成生物学领域构建高效细胞工厂的新方法,具有较高的国际影响力,形成了创新型基础研究与成果转化并重的特色。

近期论文

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Cheng, L., Zhang, F., Wang, S., Pan, X., Han, S., Liu, S., Ma, J., Wang, H., Shen, H., Liu, H.*, Yuan, Q.*. NIR-Triggered Exogenous Enzymes to Convert Prodrugs for Locoregional Chemo-Photothermal Therapy. Angewandte Chemie International Edition, 58, 1-6 (2019). Li, W., Ma, L., Shen, X., Wang J., Feng, Q., Liu, L., Zheng, G., Yan, Y., Sun, X.*, Yuan, Q.*. Targeting metabolic driving and intermediate influx in lysine catabolism for high-level glutarate production. Nature Communications, (2019). Xie, R., Li, Y., Tang, P., & Yuan, Q. Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents. Eur. J. Med. Chem. 143, 320-333 (2018). Wang, J., Shen, X., Yuan, Q.*, Yan, Y*. Microbial synthesis of pyrogallol using genetically engineered Escherichia coli. Metabolic engineering, 45, 134-141 (2018). Chen, Z., Sun, X.*, Li, Y., Yan, Y., & Yuan, Q.*. Metabolic engineering of Escherichia coli for microbial synthesis of monolignols. Metabolic engineering, 39, 102-109 (2017). Wang, J., Shen, X., Jain, R., Wang, J., Yuan, Q.*, Yan, Y*. Establishing a novel biosynthetic pathway for the production of 3, 4-dihydroxybutyric acid from xylose in Escherichia coli. Metabolic engineering. 41, 39-45 (2017). Shen, X., Wang, J., Wang, J., Chen, Z., Yuan, Q., & Yan, Y. High-level de novo biosynthesis of arbutin in engineered Escherichia coli. Metabolic engineering, 42, 52-58 (2017). Shen, X., Mahajani, M., Wang, J., Yang, Y., Yuan, Q., Yan, Y., & Lin, Y. Elevating 4-hydroxycoumarin production through alleviating thioesterase-mediated salicoyl-CoA degradation. Metabolic engineering, 42, 59-65 (2017). Sun, J., Lin, Y., Shen, X., Jain, R., Sun, X., Yuan, Q., & Yan, Y. Aerobic biosynthesis of hydrocinnamic acids in Escherichia coli with a strictly oxygen-sensitive enoate reductase. Metabolic engineering, 35, 75-82 (2016). Sun, X., Shen, X., Jain, R., Lin, Y., Wang, J., Sun, J., Wang, J., Yan, Y.*, Yuan, Q.*. Synthesis of chemicals by metabolic engineering of microbes. Chemical Society Reviews. 44, 3760-3785 (2015).

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