个人简介
B.S., Wayne State Univeristy; Ph.D., New York University Courant Institute of Mathematical Sciences; Postdoctoral research, NYU and Weizmann Institute, Israel
研究领域
Molecular mechanics and dynamics/computational and structural biology/DNA supercoiling/RNA structure and genomics/and DNA/protein interactions. Biomolecular Modeling/Computational Biology Courses
Molecular mechanics and dynamics, computational and structural biology, DNA supercoiling, RNA structure and genomics, and DNA/protein interactions. Biomolecular Modeling, Computational Biology Courses
近期论文
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S. S. P. Rao, S.-C Huang, B. G. St. Hilaire, J. M. Engreitz, E. M. Perez, K.-R Kieffer-Kwon, A. L. Sanborn, S. E. Johnstone, G. D. Bascom, I. D. Bochkov, X. Huang, M. S. Shamim, J. Shin, D. Turner, A. D. Omer, J. T. Robinson, T. Schlick, B. E. Bernstein, R. Casellas, E. Lander, and E. Lieberman-Aiden, “Cohesin Loss Eliminates All Loop Domains, Leading to Links Among Superenhancers and Downregulation of Nearby Genes”, Cell 171: 305–320 (2017).
T. Schlick, “Adventures with RNA Graphs”, Submitted to Biophysics of RNA-Protein Interactions, D. Rueda and C. Joo, Editors, Springer Verlag, New York.
S. Jain and T. Schlick, “F-RAG: Generating Atomic Coordinates from RNA Graphs by Fragment Assembly”, J. Mol. Biol. 429: 3587–3605 (2017).
L. Petingi and T. Schlick, “Partitioning and Classification of RNA Secondary Structures into Pseudonotted and Pseudoknot-free Regions Using a Graph-Theoretical Approach”, IAENG [Int. Assoc. Eng.] Intl. J. Comp. Sci., 44 (2): 241–246 (2017).
O. Perisic and T. Schlick, “Dependence of the Linker Histone and Chromatin Condensation on the Nucleosome Environment”, J. Phys. Chem. B 121: 7823–7832 (2017).
C. V Bayrak, N. Kim, and T. Schlick, “RNA Structure Prediction with Knowledge-Based Statistical Potentials for Kink-Turn Motifs”, Nuc. Acids Res. 45 (9): 5414–5422s (2017). [doi: 10.1093/nar/gkx045]
G. Bascom, T. Kim, and T. Schlick, “Kilobase Pair Chromatin Fiber Contacts Promoted by Living-System-Like DNA Linker Length Distributions and Nucleosome Depletion”, J. Phys. Chem. B Special Issue in Memory of Klaus Schulten 121 (15): 3882–3894 (2017). [Published onlineMarch 16, DOI: 10.1021/acs.jpcb.7b00998]
G. Bascom and T. Schlick, “Mesoscale Modeling of Chromatin Fibers”, Chapter 4, pp. 123–148, Nuclear Architecture and Dynamics, C. Lavelle and J.-M. Victor, Eds., Academic Press, Elsevier (2017).
T. Schlick and A. Pyle, “Opportunities and Challenges in RNA Structure Modeling and Design”, Biophys. J. 113: 225–234 (2017).
T. Schlick and L. Loew, “Unraveling Genome Biophysics”, Biophys. J. 112: E1–E2 (2017).
G. Bascom and T. Schlick, “Linking Chromatin Fibers to Gene Folding by Hierarchical Looping”, Biophys. J. 112: 434–445 (2017).