个人简介
于常海，北京大学神经科学研究所副所长、教授、博士生导师，北京大学感染病中心教授，北京大学系统生物学研究所转化医学实验室主任，教育部和卫生部神经科学重点实验室副主任，北京神经科学学会理事长，中国神经科学学会常务理事，香港生物科技协会主席。曾获“香港工业奖——科技成就奖”、“中华医学科技奖”、“亚洲十大知识领袖奖”、亚太弗若斯特沙利文体外诊断产品区分杰出奖等。于常海博士在国际上确立了星形胶质细胞在中枢神经功能中的重要地位，成为脑功能研究的重要基石；突破性地开发出世界上最灵敏的核酸检测技术。参与国内外研究基金项目数十项，包括参与多项国家自然科学基金项目、国家“863”计划、“973”计划和北京市自然科学基金项目。获得授权专利51项、主编了4部编著，发表论文共计147篇，SCI收录100余篇，培养研究生和博士后数十人。担任多个学术刊物，包括《Neurochemical Research》、《中华医学杂志》（英文版）、《Neuroscience Bulletin》和《生理科学进展》等的编委。
研究领域
神经元发育相关蛋白（NDAP）的功能研究
激活的星形胶质细胞的内吞机制
多聚磷酸盐在中枢神经系统中的研究
脑缺血预处理上调神经保护蛋白的机制研究
谷氨酸对星形胶质细胞及细胞核的功能影响
星形胶质细胞为靶点阐明慢性疼痛的机制研究
开发高灵敏度的分子检测和临床诊断方法
近期论文
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1. Wu Z, Wang Q, Feng Q, Liu Y, Teng J, Yu AC, Chen J.(2010) Correlation of the virulence of CSFV with evolutionary patterns of E2 glycoprotein.Front Biosci (Elite Ed). 2010 Jan 1;2:204-20.
2. Yan Dong, Rui Zhao, Xiao Qian Chen, Albert Cheung Hoi Yu. (2010) 14-3-3γ and Neuroglobin are New Intrinsic Protective Factors for Cerebral Ischemia. Molecular Neurobiology. 41:218-231
3. Yan Dong, Hua Dong Liu1, Rui Zhao, Chun Zhang Yang, Xiao Qian Chen, Xin Hong Wang, Lok Ting Lau, Jianguo Chen, Albert Cheung Hoi Yu.(2009)Ischemia activates JNK/c-Jun/AP-1 pathway to up-regulate 14-3-3 in astrocyte. Journal of Neurochemistry. 109(Suppl.1)182-188
4. AlbertCheungHoiYu, Mary McKenna and Arne Schousboe.(2009)Third ISN Special Neurochemistry Conference/8th International Meeting for Brain Energy Metabolism
5. Zhen Yu Xu, Hua Dong Liu, Lok Ting Lau, Zhang Yingge, Rui Zhao, Geng Lei Tong, Pak Ho Chan, Albert Cheung Hoi Yu.(2009)Responses of Astrocyte to Simultaneous Glutamate and Arachidonic Acid Treatment. Neurochemistry International. 55:143-150
6. 魏峥，聂琰晖，刘乐庭，卢洁，于常海.(2009)多聚磷酸盐在原核和真核生物中的研究进展.生理科学进展. 40（3）：197-202
7. 赵睿，高凯，于常海.(2009)脑能量代谢研究的回顾与前瞻.科学.61(3):11-14
8. 魏峥，于常海. Arthur Kornberg教授：科技创新的伟大科学家.(2009)生理科学进展.40（3）：281-282
9. 郭素红 卢洁 于常海. (2009) 生物标记检测在神经胶质瘤诊断中的研究进展. 吉林医药学院学报. 30 (6): 352-357
10. Hu JS, Teng JL, Ding NZ, He M, Sun YH, Yu ACH, Chen JG. (2008) FAAP, a novel murine protein, is involved in cell adhesion through regulating vinculin-paxillin association. FRONTIERS IN BIOSCIENCE. 13: 7123-7131
11. Yu AC, Wan Y, Chui DH, Cui CL, Luo F, Wang KW, Wang XM, Wang Y, Wu LZ, Xing GG, Han JS. (2008) The Neuroscience Research Institute at Peking University: A Place for the Solution of Pain and Drug Abuse. Cell Mol Neurobiol. 28(1): 13-19.
12. Lau LT, Reid SM, King DP, Lau AMF, Shaw AE, Ferris NP, Yu ACH. (2008) Detection of foot-and-mouth disease virus by nucleic acid sequence-based amplification (NASBA). Veterinary Microbiology. 126:101–110.
13. Chun Zhang Yang; Rui Zhao; Yan Dong; Xiao Qian Chen; Albert Cheung Hoi Yu. (2008) Astrocyte and Neuron Intone through Glutamate. Neurochemical Research.33:2480-2486
14. Zhao YY,Lu M, Lau LT, Lu J, Gao ZF,Liu JH,Yu ACH,Cao Q,Ye JX ,McNutt MA.,and Gu J(2008) Neutrophils May Be a Vehicle for Viral Replication and Dissemination in Human H5N1 Avian Influenza.Clinical Infectious Diseases 2008; 47:1575–1578
15.Yu ACH(2008) Preface-A tribute to professor Ji-sheng Han. Neurochemical Research. 33(10): 1911-1914
16. 王昕虹, 柳华东, 卢洁, 于常海.(2008)脑缺血性疾病中星形胶质细胞保护机制的研究. 医学研究杂志.37(3):65-66
17. 王均辉,孙峰波,秦绿叶,岳鑫,于常海.(2008)异常活化的小胶质细胞的特征与功能.生理科学进展. 39(1)：41-44
18. 曹彬,李冉,刘颖梅,曹志新,耿秀琴,刘乐庭,卢洁,巫琳,崔树峰,白瑞婷,于常海,王辰. (2008)流感样疾病的病原学与治疗及预后的关系.中华结核和呼吸杂志.31(7):483-487
19. 岳鑫，王均辉，秦绿叶，于常海.(2008)HCN通道在中枢神经系统中的功能.生理科学进展. 39(3):247-250
20. Gu J, Xie ZG, Gao ZC, Liu JH, Korteweg C, Ye JX, Lau LT, Lu J, Gao ZF, Zhang B, McNutt MA, Lu M, Anderson VM, Gong E, Yu ACH, Lipkin WI. (2007) H5N1 infection of the respiratory tract and beyond: a molecular pathology study. Lancet. 370: 1137-1145.
21. He Y, Li HL, Xie WY, Yang CZ, Yu AC, Wang Y. (2007) The presence of active Cdk5 associated with p35 in astrocytes and its important role in process elongation of scratched astrocyte. Glia. 2007 Apr 15;55(6):573-583.
22. Yu AC, Liu RY, Zhang Y, Sun HR, Qin LY, Lau LT, Wu BY, Hui HK, Heung MY, Han JS. (2007) Glial cell line-derived neurotrophic factor protects astrocytes from staurosporine- and ischemia- induced apoptosis. J Neurosci Res. 85:3457-3464.
23. Wang AL, Yu AC, He QH, Zhu X, Tso MO. (2007) AGEs mediated expression and secretion of TNF alpha in rat retinal microglia. Exp Eye Res. 84(5):905-913.
24. Wang AL, Li Z, Yuan M, Yu AC, Zhu X, Tso MO. (2007) Sinomenine inhibits activation of rat retinal microglia induced by advanced glycation end products. Int Immunopharmacol. 7(12):1552-1558.
25. Li D, Chen XQ, Li WJ, Yang YH, Wang JZ, Yu AC. (2007) Cytoglobin Up-regulated by Hydrogen Peroxide Plays a Protective Role in Oxidative Stress. Neurochem Res. 32:1375-1380.
26. Cui SJ, Fung YWW, Lau LT, Liu WB, Wang YF, Tong GZ, Chen JG, Yu AC. (2007) Detection of Newcastle Disease virus using nucleic acid sequence-based amplification. Biologicals. 35(1):13-18.
27. LIU HD, LIU S, LI HL, CHEN XQ, YU ACH (2007) Activation of Signal Transduction Pathways after Cerebral Ischemia. Chinese Journal of Biochemistry and Molecular Biology 23(1): 33-37.
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