伊鸣 - 北京大学 - 神经科学研究所

个人简介

于北京大学医学部临床医学专业获医学学士学位，英国伦敦大学学院（University College London, UCL）解剖与发育生物学系神经科学专业获哲学博士学位（导师John O’Keefe教授，英国皇家科学院、皇家医学院、美国科学院院士，2014年诺贝尔生理学或医学奖获得者）。现任北京大学神经科学研究所认知神经科学实验室研究员。

研究领域

记忆的精准操控与功能重建

近期论文

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Shao S, Zheng Y, Fu Z, Wang J, Zhang Y, Wang C, Qi X, Gong T, Ma L, Lin X, Yu H, Wan Y, Zhang H, Yi M. Ventral hippocampal CA1 modulates pain behaviors in mice with peripheral inflammation. Cell Rep. 2023; 42(1): 112017. Qi X, Cui K, Zhang Y, Wang L, Tong J, Sun W, Shao S, Wang J, Wang C, Sun X, Xiao L, Xi K, Cui S, Liu F, Ma L, Zheng J, Yi M, Wan Y. A nociceptive neuronal ensemble in dorsomedial prefrontal cortex underlies pain chronicity. Cell Rep. 2022; 41(11):111833. Sun H, Fu S, Yin X, Sun X, Qi X, Cui K, Wang J, Ma L, Liu FY, Cui S, Liao FF, Wang XH, Yi M, Wan Y. Development of CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain. Sci Adv. 2020; 6: eaay6687. Ma L, Yue L, Zhang Y, Wang Y, Han B, Cui S, Liu FY, Wan Y, Yi M. Spontaneous pain disrupts ventral hippocampal CA1-infralimbic cortex connectivity and modulates pain progression in rats with peripheral inflammation. Cell Rep. 2019;29:1579–1593. Ma L, Zhang Y, Yue L, Zhang X, Cui S, Liu F, Wan Y, Yi M. Anterior cingulate cortex modulates the affective-motivative dimension of hyperosmolality-induced thirst. J Physiol. 2019; 597(18):4851-4860. Jiang Y, Shao S, Zhang Y, Zheng J, Chen X, Cui S, Liu FY, Wan Y, Yi M. Neural pathways in medial septal cholinergic modulation of chronic pain: distinct contribution of anterior cingulate cortex and ventral hippocampus. Pain. 2018. 159(8):1550-1561. Peng WW, Xia XL, Yi M, Huang G, Zhang ZG, Iannetti GD, Hu L. Brain oscillations reflecting pain-related behavior in freely moving rats. Pain. 2018. 159(1):106–118. Fan XC, Fu S, Liu FY, Cui S, Yi M, Wan Y. Hypersensitivity of prelimbic cortex neurons contributes to aggravated nociceptive responses in rats with experience of chronic inflammatory pain. Front Mol Neurosci. 2018. 11:85. Zheng J, Jiang YY, Xu LC, Ma LY, Liu FY, Cui S, Cai J, Liao FF, Wan Y, Yi M. Adult hippocampal neurogenesis along the dorsoventral axis contributes differentially to environmental enrichment combined with voluntary exercise in alleviating chronic inflammatory pain in mice. J Neurosci. 2017; 37(15):4145-4157. Liu Y, Lai S, Ma W, Ke W, Zhang C, Liu S, Zhang Y, Pei F, Li S, Yi M, Shu Y, Shang Y, Liang J, Huang Z. CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression. Nat Commun. 2017;8(1):355. Xiao X, Zhao XT, Xu LC, Yue LP, Liu FY, Cai J, Liao FF, Kong JG, Xing GG, Yi M, Wan Y. Shp-1 dephosphorylates TRPV1 in dorsal root ganglion neurons and alleviates CFA-induced inflammatory pain in rats. Pain. 2015; 156(4): 597-608. Yi M, Zhang H. Nociceptive memory in the brain: cortical mechanisms of chronic pain. J Neurosci. 2011. 31:13343-13345. Cacucci F *, Yi M *, Wills TJ, Chapman P, O'Keefe J. Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model. Proc Natl Acad Sci U S A. 2008; 105(22): 7863-8.