个人简介
何旺骁,男,1991年生,2019年入选西安交通大学“青年拔尖人才”支持计划,西安交通大学特聘研究员,博士生导师。2019年博士科毕业于西安交通大学生命科学与技术学院。近5年(截至2019年7月)发表SCI/EI期刊28篇, 其中领域内顶级期刊(IF>8)15篇, JCR 1区刊物 16篇;以第一或通讯作者发表论文14篇(累积IF>100),其中领域IF>10的7篇,ESI高被引论文1篇
研究领域
(1)靶向蛋白质相互作用的药物开发
(2)基于蛋白质全化学合成的蛋白质功能研究
(3)多肽药物的设计与成药策略
近期论文
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He W, Wang S, Yan J, Qu Y, Jin L, Sui F, Li Y, You W, Yang G, Yang Q, Ji M, Shao Y, Ma P, Lu W, Hou P. Self-Assembly of Therapeutic Peptide into Stimuli‐Responsive Clustered Nanohybrids for Cancer‐Targeted Therapy. Advanced Functional Materials. 2019 Mar; 29(10):1807736. [JCR一区 ; IF =15.621]
He W, Yan J, Wang L, Lei B, Hou P, Lu W, Ma PX. A lanthanide-peptide-derived bacterium-like nanotheranostic with high tumor-targeting,-imaging and-killing properties. Biomaterials. 2019 Jun 1; 206:13-24.. [JCR一区 ; IF =10.273]
He W*(第一兼通讯作者), Yan J, Sui F, Wang S,Su X, Qu Y, Yang Q, Guo H, Ji M, Lu W, Shao Y*, Hou P*. Turning a Luffa protein into a self-assembled biodegradable nanoplatform for multitargeted cancer therapy. ACS nano, 2018, 12(11): 11664-11677. [JCR一区 ; IF =13.903]
He W, Yan J, Jiang W, Li S, Qu Y, Niu F, Yan Y, Sui F, Wang S, Zhou L, Jin L, Li Y, Ji M, Ma PX, Lin M*, Lu W*, Hou P*. Peptide-Induced Self-Assembly of Therapeutics into a Well-Defined Nanoshell with Tumor-Triggered Shape and Charge Switch. Chemistry of Materials, 2018, 30(20), 7034-7046. [JCR一区 ; IF =10.159]
Bian Z, Yan J, Wang S, Li Y, Guo Y, Ma B, Guo H, Lei Z, Yin C, Zhou Y, Liu M, Tao K*, Hou P*, He W(通讯作者)*. Awakening p53 in vivo by D-peptides-functionalized ultra-small nanoparticles: Overcoming biological barriers to D-peptide drug delivery. Theranostics, 2018, 8(19): 5320.. [JCR一区 ; IF =8.063]
Niu F, Yan J, Ma B, Li S, Shao Y, He P, Zhang W, He W*(通讯作者), Ma PX*, Lu W*. Lanthanide-doped nanoparticles conjugated with an anti-CD33 antibody and a p53-activating peptide for acute myeloid leukemia therapy. Biomaterials, 2018, 167: 132-142. [JCR一区 ; IF =10.273]
Yan J†, He W†*(共同第一兼通讯作者), Yan S, Niu F, Liu T, Ma B, Shao Y, Yan Y, Yang G, Lu W, Du Y. Self-assembled peptide–lanthanide nanoclusters for safe tumor therapy: overcoming and utilizing biological barriers to peptide drug delivery. ACS nano. 2018 Feb 2;12(2):2017-26. [JCR一区 ; IF =13.903]
Yan J†, He W†(共同第一作者), Li N, Yu M, Du Y, Lei B, Ma PX. Simultaneously targeted imaging cytoplasm and nucleus in living cell by biomolecules capped ultra-small GdOF nanocrystals. Biomaterials. 2015 Aug 1; 59:21-9.[JCR一区 ; IF =10.273]