Kim, Eunsuk - Brown University - Department of Chemistry

个人简介

B.S. in Chemistry (1994), Sangmyung University, Seoul, Korea M.S. in Inorganic Chemistry (1996), Korea University, Seoul, Korea (Advisor: Ho G. Jang) Ph.D. in Inorganic Chemistry (2004), Johns Hopkins University (Advisor: Kenneth D. Karlin) Postdoctoral Fellow (2004-2005), Harvard University, School of Public Health (Advisor: Bruce Demple) Postdoctoral Fellow (2005-2008), MIT, Biological Engineering Department (Advisor: John M. Essigmann)

研究领域

The research projects in the Kim lab are in the area of bioinorganic chemistry with a goal of developing fundamental inorganic chemistry to address challenging biological and environmental problems and questions. Toward this goal, our research program will use a multidisciplinary approach, drawing from synthetic inorganic chemistry, spectroscopy, biochemistry, and toxicology.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Tran, C.T.; Williard, P.G.; Kim, E. "Nitric Oxide Reactivity of [2Fe-2S] Clusters Leading to H2S Generation" - J. Am. Chem. Soc. 2014, 136 (34), pp 11874-11877 Fitzpatrick. J.; Kalyvas, H.; Filipovic, M.R.; Ivanović-Burmazović, I.; MacDonald, J.C.; Shearer, J.; Kim, E. "Transformation of a Mononitrosyl Iron Complex to a [2Fe-2S] Cluster by a Cysteine Analogue" - J. Am. Chem. Soc. 2014, 136 (20), pp 7229-7232 Skodje, K.M.; Kwon, M-Y; Chung, S.W.; Kim, E. "Coordination-Triggered NO Release from a Dinitrosyl Iron Complex leads to Anti-Inflammatory Activity" - Chem Sci. 2014, 5, pp 2374-2378 Tran, C.T.; Skodje, K.M.; Kim, E. "Synthetic Monomeric Dinitrosyl Iron Complexes: Synthesis and Reactivity" - Progress in Inorganic Chemistry, Karlin, K.D., Ed.; Wiley:New Jersey, 2013, vol. 58, Accepted Manuscript Seo, J.; Williard, P.G.; Kim, E. "Deoxygenation of Mono-oxo Bis(dithiolene) Mo and W Complexes by Protonation" - Inorg. Chem. 2013, 52, pp 8706-8712. Fitzpatrick, J.; Kalyvas, H.; Shearer, J.; Kim, E. "Dioxygen mediated conversion of {Fe(NO)2}9 dinitrosyl iron complexes to Roussin's red esters" - Chem. Commun., 2013, 49, pp 5550-5552. Tran, C.T.; Kim, E. "Acid-Dependent Degradation of a [2Fe-2S] Cluster by Nitric Oxide" - Inorg. Chem., 2012, 51,10086-10088. Seo, J.; Kim, E. "O-Atom Exchange between H2O and CO2 Mediated by a Bis(dithiolene)tungsten Complex" - Inorg. Chem., 2012, 51, 7951-7953. Skodje, K.M.; Williard, P. G.; Kim, E. "Conversion of {Fe(NO)2}10 dinitrosyl iron to nitrato iron(III) species by molecular oxygen" - Dalton Transactions, 2012, 41, 7849-7851. Tran, N.G; Kalyvas, H.; Skodje, K.M.; Hayashi, T.; Moënne-Loccoz, P.; Callan, P.E.; Shearer, J.; Kirschenaum, L.J.; Kim. E. "Phenol Nitration Induced by an {Fe(NO)2}10 Dinitrosyl Iron Complex" J. Am. Chem Soc., 2011, 133, 1184-1187. Liu, C.; Kim, E.; Demple, B.; Seeman, N.C. "A DNA-Based Nanomechanical Device Used to Characterize the Distortion of DNA by Apo-SoxR Protein" Biochemistry, 2012, 51, 937-943. Kim, E.; Rye, P.T.; Croy, R.G.; Essigmann, J.M. "Programmable Platinum Antitumor Agents for Ovarian and Breast Cancers" J. Inorg. Biochem., 2009, 103, 256-261. Chufán, E.E.; Mondal, B.; Gandhi, T.; Kim, E.; Rubie, N; Moënne-Loccoz, P.; Karlin, K.D. "Reactivity Studies on FeIII-(O22–)-CuII Compounds: Influence of the Ligand Architecture and Copper Ligand Denticity" Inorg. Chem., 2007, 46, 6382-6394. Kim, E.; Helton, M.E.; Lu, S.; Moënne-Loccoz, P.; Incarvito, C.D.; Rheingold, A.L.; Kaderli, S.; Zuberbühler, A.D.; Karlin, K.D. "Tridentate Copper Ligand Influences on Heme-Peroxo-Copper Formation and Properties: Reduced, Superoxo, and μ-Peroxo Fe/Cu Complexes." Inorg. Chem., 2005, 44, 7014-7029. Kim, E.; Kamaraj, K.; Galliker, B.; Rubie, N.D.; Moënne-Loccoz, P.; Kaderli, S.; Zuberbühler, A.D.; Karlin, K.D. "Dioxygen Reactivity of Copper and Heme-Copper Complexes Possessing an Imidazole-Phenol Cross-Link." Inorg. Chem., 2005, 44, 1238-1247. Kim, E.; Shearer, J.; Lu, S.; Moënne-Loccoz, P.; Helton, M.E.; Kaderli, S.; Zuberbühler, A.D.; Karlin, K.D. "Heme/Cu/O2 Reactivity: Change in FeIII-(O22–)-CuII Unit Peroxo Binding Geometry Effected by Tridentate Copper Chelation." J. Am. Chem Soc., 2004, 126, 12716-12717. Kim, E.; Chufán, E.E.; Kamaraj, K.; Karlin, K.D. "Synthetic Models for Heme-Copper Oxidases." Chem. Rev., 2004, 104, 1077-1133. Karlin, K.D.; Kim, E. "Ligand influences in heme-copper O2-chemistry as synthetic models for cytochrome c oxidase." Chem. Lett., 2004, 33, 1226-1231. Kamaraj, K.; Kim, E.; Galliker, B.; Zakharov, L.N.; Rheingold, A.L.; Zuberbühler, A.D.; Karlin, K.D. "Copper(I) and Copper(II) Complexes Possessing Cross-Linked Imidazole-Phenol Ligands: Structures and Dioxygen Reactivity." J. Am. Chem Soc., 2003, 125, 6028-6029. Kim, E.; Helton, M.E.; Wasser, I.M.; Karlin, K.D.; Lu, S.; Huang, H-w.; Moënne-Loccoz, P.; Incarvito, C.D.; Rheingold, A.L.; Honecker, M.; Kaderli, S.; Zuberbühler, A.D. "Superoxo, μ-peroxo and μ-oxo complexes from heme/O2 and heme-Cu/O2 reactivity: Copper-ligand influences in cytochrome c oxidase models." Proc. Natl. Acad. Sci. USA, 2003, 100, 3623-3628. Zhang, C.X.; Liang, H.-C.; Kim, E.-i.; Shearer, J.; Helton, M.E.; Kim, E.; Kaderli, S.; Incarvito, C.D.,; Zuberbühler, A.D.; Rheingold, A.L.; Karlin, K.D. "Tuning Copper-Dioxygen Reactivity and Exogenous Substrate Oxidation via Alterations in Ligand Electronics" J. Am. Chem Soc., 2003, 125, 634-635. Liang, H-C.; Kim, E.; Incarvito, C.D.; Rheingold, A.L.; Karlin, K.D. "A Bis-Acetonitrile Two-Coordinate Copper(I) Complex: Synthesis and Characterization of Highly soluble B(C6F5)4-Salts of [Cu(MeCN)2]+ and [Cu(MeCN)4]+." Inorg. Chem., 2002, 41, 2209-2212. Kim, E.; Lee, K-B.; Jang, H.G. "Dioxygen Binding to the Singly Alkoxo-Bridged Diferrous Complex: Properties of [FeII2(N-Et-HPTB)Cl2]BPh4." Bull. Korean. Chem. Soc., 1996, 17, 1127-1131.