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基于T细胞基因工程操作研究和开发安全高效的肿瘤免疫治疗产品

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1. Zhu, X. and Niedermann, G. (2015). Rapid and efficient transfer of the T cell aging marker CD57 from glioblastoma stem cells to CAR T cells. Oncoscience 2,476-482. 2. Zhu, X., Prasad, S., Gaedicke, S., Hettich, M., Firat, E., and Niedermann, G. (2015). Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57. Oncotarget 6, 171-184. 3. Gaedicke, S., Braun, F., Prasad, S., Machein, M., Firat, E., Hettich, M., Gudihal, R., Zhu, X., Klingner, K., Schuler, J., Herold-Mende, C.C., Grosu, A.L., Behe, M., Weber, W., Macke, H., and Niedermann, G. (2014). Noninvasive positron emission tomography and fluorescence imaging of CD133+ tumor stem cells. Proc Natl Acad Sci U S A 111, E692- 701. 4. Zhang, G., Liu, R., Zhu, X., Wang, L., Ma, J., Han, H., Wang, X., He, W., Wang, W., Liu, C., Li, S., Sun, M., and Gao, B. (2013). Retargeting NK-92 for anti-melanoma activity by a TCR-like single-domain antibody. Immunol Cell Biol 91, 615-624. 5. Wang, L., Liu, X., Zhu, X., Wang, W., Liu, C., Cui, H., Sun, M., and Gao, B. (2013). Generation of single-domain antibody multimers with three different self-associating peptides. Protein Eng Des Sel 26, 417-423. 6. Zhu, X., Wang, L., Liu, R., Flutter, B., Li, S., Ding, J., Tao, H., Liu, C., Sun, M., and Gao, B. (2010). COMBODY: one-domain antibody multimer with improved avidity. Immunol Cell Biol 88, 667-675.

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