研究领域
长期从事临床医学基础研究、心血管疾病小动物模型的应用和膜磷脂代谢在心血管疾病的转化研究。
近期论文
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1. Yang Q, Shi M, Shen Y, Cao Y, Zuo S, Zuo C, Zhang H, Gabrilovich DI, Yu Y*, Zhou J*. COX-1 derived thromboxane A2 plays an essential role in early B cell development via regulation of JAK/STAT5 signaling in mouse. Blood. 2014 Sep 4;124(10):1610-21.
2. Yan S, Zhang Q, Zhong X, Tang J, Wang Y, Yu J, Zhou Y, Zhang J, Guo F, Liu Y, FitzGerald GA, Yu Y*. I prostanoid receptor-mediated inflammatory pathway promotes hepatic gluconeogenesis through activation of PKA and inhibition of AKT. Diabetes. 2014 Sep;63(9):2911-23.
3. Shi M, Shi G, Tang J, Kong D, Bao Y, Xiao B, Zuo C, Wang T, Wang Q, Shen Y, Wang H, Funk CD, Zhou J, Yu Y*. Myeloid-derived suppressor cell function is diminished in aspirin-triggered allergic airway hyper-responsiveness. J Allergy Clin Immunol. 2014 Jun 17. pii: S0091-6749(14)00656-3.
4. Zhang J, Zou F, Tang J, Zhang Q, Gong Y, Wang Q, Shen Y, Xiong L, Breyer RM, Lazarus M, Funk CD, Yu Y*. COX-2-Derived PGE2 Promotes Injury-induced Vascular Neointimal Hyperplasia through the EP3 Receptor. Circ Res. 2013; 113(2):104-14.
5. Yu Y*(Corresponding author), Ricciotti E, Scalia R, Tang SY, Grant G, Yu Z, Landesberg G, Crichton I, Wu W, Puré E, Funk CD, FitzGerald GA*. Vascular COX-2 Modulates blood pressure and thrombosis in vivo. Sci Transl Med. 2012; 4(132):132ra54