研究领域
1.肿瘤分子靶点和营养药学的应用基础研究:发现肿瘤人群易感标志物和诊断治疗新靶点,研究靶点功能及其分子调控和信号转导,探索以膳食营养素、天然植物活性成份、化学小分子探针等靶向干预和治疗肿瘤的新机制和新方法。 2.营养和食品安全的基础和应用研究:营养成分安全性评价及毒理学研究,营养素和营养素物质的安全剂量,过量时的毒理作用以及机制;食物中有毒有害物质代谢途径和致病机理,食品安全风险评估、预防控制和检测新技术研究。
近期论文
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1. Ba Q, Hao M, Huang H, Hou J, Ge S, Zhang Z, Yin J, Chu R, Jiang H, Wang F, Chen K, Liu H and Wang H*. Iron deprivation suppresses hepatocellular carcinoma growth in experimental studies. Clin Cancer Res. 2011;17(24):7625-33.
2. Chen P, Hu P, Xie D, Qin Y, Wang F, and Wang H*. Meta-analysis of Vitamin D, Calcium and the Prevention of Breast Cancer. Breast Cancer Res Treat. 2010;121(2):469-77.
3. Chen T, Li M, Zhang R, and Wang H*. Dihydroartemisinin Induces Apoptosis and Sensitizes Human Ovarian Cancer Cells to Carboplatin Therapy. J Cell Mol Med. 2009;13(7):1358-70.
4. Chen P, Liang J, Wang Z, Zhou X, Chen L, Li M, Xie D, Hu Z, Shen H, and Wang H*. Association of Common PALB2 Polymorphisms with Breast Cancer Risk: a Case-Control Study. Clin Cancer Res. 2008; 14 (8): 5931-37.
5. Hou J, Wang D, Zhang R, and Wang H*. Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action. Clin Cancer Res. 2008;14(17):5519-30.