杜卫华 - 中国农业科学院北京畜牧兽医研究所 -

个人简介

2001年获山西农业大学农学硕士学位；2004年获中国农业大学理学博士学位。2004年至今在中国农业科学院北京畜牧兽医研究所工作。现任畜牧兽医学会繁殖学分会理事。

研究领域

主要研究动物胚胎（体外受精、体细胞克隆）体外发育机理，从胚胎转录组、表观遗传组学等多维度解析胚胎发育调控机制；同时研究抗氧化剂清除胚胎氧化应激的机制，提高体外胚胎的发育率和质量；采用CRISPR-Cas9等基因编辑技术研发基因精准修饰转基因奶牛和抗病育种转基因牛新品种。建立了体细胞克隆新方法（无透明带卵母细胞克隆法），成功获得种公牛克隆后代，这是我国首次应用无透明带方法获得的克隆动物。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Feng Li, Lixin Cui, Dawei Yu, Haisheng Hao, Yan Liu, Xueming Zhao, Yunwei Pang, Huabin Zhu, Weihua Du*. Exogenous glutathione improves synthesis of intracellular glutathione via the γ-glutamyl cycle in bovine zygotes and cleavage embryos, Journal of Cellular Physiology, 2019, 234:7384-7394. Xueming Zhao, Haisheng Hao, Weihua Du, Shanjiang Zhao, Haoyu Wang, Na Wang, Dong Wang, Yan Liu, Tong Qin, Huabin Zhu. Melatonin inhibits apoptosis and improves the developmental potential of vitrified bovine oocytes. J Pineal Res. 2016. 60(2):132-141. Tingxi Hu, Huabin Zhu, Weijun Sun, Haisheng Hao, Xueming Zhao, Weihua Du*, Zongli Wang. Sperm pretreatment with glutathione improves IVF embryos development through increasing the viability and antioxidative capacity of sex-sorted and unsorted bull semen, Journal of Integrative Agriculture, 2016, 15:2326-2335. Weijun Sun, Qinqin Guo, Yan Liu, Haisheng Hao, Xueming Zhao, Tong Qin, Huabin Zhu, Weihua Du*. Effects of exogenous glutathione supplementation on bovine embryo development after in vitro fertilization, Theriogenology, 2015, 84:716-723. Xia Liu, Tingxi Hu, Weijun Sun, Haisheng Hao, Yan Liu, Xueming Zhao, Tong Qin, Huabin Zhu, Weihua Du*. Comparison of the developmental competence and quality of bovine embryos fertilized in vitro with sex-sorted and unsorted semen from seven bulls, Livestock Science, 2015, 181:263-270. Dawei Yu, Shoufeng Zhang, Weihua Du*, Jinxia Zhang, Zongxin Fan, Haisheng Hao, Yan Liu, Xueming Zhao, Tong Qin, Huabin Zhu. Expression of intracellular interferon-alpha confers antiviral properties in transfected bovine fetal fibroblasts and does not affect the full development of SCNT embryos, PLoS One, 2014, 9:1457-1453. Xueming Zhao, Weihua Du, Haisheng Hao, Dong Wang, Tong Qin, Huabin Zhu. Effect of vitrification on promoter methylation and the expression of pluripotency and differentiation genes in mouse blastocysts. Mol Reprod Dev. 2012;79(7):445-50.

学术兼职

现任胚胎工程与动物繁殖团队骨干专家，畜牧兽医学会繁殖学分会理事。