研究领域
1.间质干细胞的免疫调节机制:间质干细胞在组织修复中具有重要作用,研究间质干细胞与免疫微环境之间的作用对了解组织修复和许多疾病发生机理十分重要; 2.肿瘤免疫学:研究重点集中在肿瘤基质(即癌细胞生存的土壤)上,以期了解其如何对肿瘤免疫的影响; 3.不同T细胞群体的AICD过程:了解不同T细胞群体的死亡机制对控制传染病、癌症和自身性免疫疾病具有重要意义。
近期论文
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1. Ren GW, et al. CCR2-dependent Recruitment of Macrophages by Tumor Educated Mesenchymal Stromal Cells Promotes Tumor Development and is Mimicked by TNF-alpha. Cell Stem Cell. 2012. 11(6):812-824.
2. Shi Y, Su J, Roberts AI, Shou P, Rabson AB, Ren G. How mesenchymal stem cells interact with tissue immune responses. Trends Immunology.2012, 33:136-43.
3. Sensebé L, Tarte K, Galipeau J, Krampera M, Martin I, Phinney DG, Shi Y. Limited Acquisition of Chromosomal Aberrations in Human Adult Mesenchymal Stromal Cells. Cell Stem Cell. 2012, 10:9-10.
4. Shi Y, Wei L, Wang Y, Ren G. Stem Cells Deployed for Bone Repair Hijacked by T Cells. Cell Stem Cell. 2012, 10:6-8.
5. Ren GW, Zhang LY, Zhao X, Xu GW, Zhang YY, Roberts AI, Zhao RC, and Shi YF. Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide. Cell Stem Cell. 2008, 2: 141-150.