研究领域
非编码RNA的功能机制(中科院上海生命科学研究院生物化学与细胞生物学研究所研究员)
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1. Lin Wang, Ling-Fei Zhang, Jing Wu, Shu-Jun Xu, Yang-Yang Xu, Dangsheng Li, Jia-Tao Lou*, Mo-Fang Liu*. IL-1β-mediated repression of microRNA-101 is crucial for inflammation-promoted lung tumorigenesis. Cancer Res, 2014, 74(17):4720-4730.
2. Lan-Tao Gou, Peng Dai, Jian-Hua Yang, Yuanchao Xue, Yun-Ping Hu, Yu Zhou, Jun-Yan Kang, Xin Wang, Hairi Li, Min-Min Hua, Shuang Zhao, Li-Gang Wu, Hui-Juan Shi, Yong Li, Xiang-Dong Fu, Liang-Hu Qu, En-Duo Wang, Mo-Fang Liu*. Pachytene piRNAs Instruct Massive mRNA Elimination during Late Spermiogenesis. Cell Res, 2014, 24(6):680-700.
3. Shuang Zhao, Lan-Tao Gou, Man Zhang, Li-Dong Zu, Min-Min Hua, Ye Hua, Hui-Juan Shi, Yong Li, Jin-Song Li, Dangsheng Li, En-Duo Wang*, Mo-Fang Liu*. piRNA-triggered MIWI ubiquitination and removal by APC/C in late spermatogenesis, Dev Cell, 2013, 24(1): 13-25.
4. Shuai Jiang, Ling-Fei Zhang, Hong-Wei Zhang, Song Hu, Ming-Hua Lu, Sheng Liang, Biao Li, Yong Li, Dangsheng Li, En-Duo Wang, Mo-Fang Liu*. A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase2 in breast cancer cells. EMBO J, 2012, 31(8):1985-1998.
5. Shuai Jiang, Hong-Wei Zhang, Ming-Hua Lu, Xiao-Hong He, Yong Li, Hua Gu, Mo-Fang Liu*, En-Duo Wang. MicroRNA-155 functions as an oncomiR in breast cancer by targeting the suppressor of cytokine signaling-1 gene. Cancer Res, 2010, 70(8): 3119-3127.