惠利健 - 上海科技大学 - 生命科学与技术学院

研究领域

以肝脏细胞为研究对象，利用细胞生物学、遗传学和基因组学手段，着力于细胞命运维持与转分化、癌化等机理研究，以图揭示细胞命运转变的调控机理，从而阐明维持细胞稳定类型和功能的分子机制，并希望能为肝癌和终末期肝病治疗提供新的思路和策略。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1) Huang, P., Zhang, L., Gao, Y., He, Z., Yao, D., Wu, Z., Cen, J., Chen, X., Liu, C., Hu, Y., Hui, L.* et al. (2014). Direct reprogramming of human fibroblasts to functional and expandable hepatocytes. Cell stem cell 14, 370-384. 2) Li, D., Cen, J., Chen, X., Conway, E.M., Ji, Y., and Hui, L.* (2013). Hepatic loss of survivin impairs postnatal liver development and promotes expansion of hepatic progenitor cells in mice. Hepatology 58, 2109-2121. 3) Ji, S., Zhang, L., and .Hui, L..* (2013). Cell fate conversion: direct induction of hepatocyte-like cells from fibroblasts. Journal of cellular biochemistry 114, 256-265. 4) Min, L., Ji, Y., Bakiri, L., Qiu, Z., Cen, J., Chen, X., Chen, L., Scheuch, H., Zheng, H., Qin, L., Zatloukal, K., .Hui, L..*, Wagner, E.F.* et al. (2012). Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin. Nature cell biology 14, 1203-1211. 5) Huang, P., He, Z., Ji, S., Sun, H., Xiang, D., Liu, C., Hu, Y., Wang, X., and .Hui, L..*(2011). Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature 475, 386-389.