研究领域
1. 细胞极性与细胞迁移、增殖和肿瘤发生的相关性研究; 2. 酪氨酸激酶细胞信号通路研究; 3. 磷酸化蛋白质组学研究。
近期论文
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1. Du D, Xu F, Yu L, Zhang C, Lu X, Yuan H, Huang Q, Zhang F, Bao H, Jia L, Wu X, Zhu X, Zhang X, Zhang Z, Chen Z*. The Tight Junction Protein, Occludin, Regulates the Directional Migration of Epithelial Cells. Developmental Cell. 2010, 18(1):52-63.
2. Yuan H, Zhang H, Wu X, Zhang Z, Du D, Zhou S, Brakebusch C, and Chen Z*. Hepatocyte-specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice. Hepatology. 2009, 49:240-249.
3. Lu XF, Feng XJ, Man XB, Yang G, Tang L, Du D, Zhang F, Yuan HX, Huang Q, Zhang Z, Liu YK, Strand D, and Chen Z*. Aberrant Splicing of Hugl-1, the Human Homologue of Drosophila Tumor Suppressor Gene lgl, is Associated with Hepatocellular Carcinoma Progression. Clin Cancer Res. 2009;15(10):3287-3296.
4. Feng X, Lu X, Man X, Zhou W, Jiang LQ, Knyazev P, Lei L, Huang Q, Ullrich A, Zhang Z*, and Chen Z*. Overexpression of Csk-binding protein (Cbp) contributes to renal cell carcinogenesis. Oncogene. 2009, 28(37):3320-31.
5. Yang G, Li Q, Ren S, Lu X, Fang L, Zhou W, Zhang F, Xu F, Zhang Z, Zeng R, Lottspeich F, and Chen Z*. Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins. Proteomics. 2009, 9(21):4944-61.